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authFullName_s : Frédéric Bihel

Substituted thiazolamide coupled to a redox delivery system: a new γ-secretase inhibitor with enhanced pharmacokinetic profile

Younes Laras , Gilles Quéléver , Cédrik Garino , Nicolas Pietrancosta , Mahmoud Sheha et al.
Organic & Biomolecular Chemistry, 2005, 3 (4), pp.612-618. ⟨10.1039/b415090b⟩
Journal articles istex hal-02351730v1

Development of a L-Tryptophan-Based Ligand for Regioselective Copper Catalyzed N 2 -Arylation of 1,2,3-Triazoles

Alexandra Basilio Lopes , Patrick Wagner , Arthur Eugen Kümmerle , Frédéric Bihel , Jean-Jacques Bourguignon et al.
ChemistrySelect, 2017, 2 (22), pp.6544-6548. ⟨10.1002/slct.201701498⟩
Journal articles hal-02368798v1

Development of a Peptidomimetic Antagonist of Neuropeptide FF Receptors for the Prevention of Opioid-Induced Hyperalgesia

Frédéric Bihel , Jean-Paul Humbert , Severine Schneider , Isabelle Bertin , Patrick Wagner et al.
ACS Chemical Neuroscience, 2015, 6 (3), pp.438-445. ⟨10.1021/cn500219h⟩
Journal articles hal-03198603v1
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Erratum to: "CMTX1 patients' cells present genomic instability corrected by CamKII inhibitors

Saleh Mones , Burkhard Gess , Benoit Bordignon , Alexandre Altie , Peter Young et al.
Orphanet Journal of Rare Diseases, 2016, 11, ⟨10.1186/s13023-015-0354-2⟩
Journal articles hal-02630248v1

Microwave-assisted cyclic amidine synthesis using TiCl4

Hellal Malik , Frédéric Bihel , Bourguignon Jean-Jacques
Journée Scientifique de l'IFR Gilbert Laustriat, 2006, Illkirch, France
Conference papers hal-00195376v1
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Human erythrocytes release ATP by a novel pathway involving VDAC oligomerization independent of pannexin-1

Irene Marginedas-Freixa , Cora Lilia Alvarez , Martina Moras , María Florencia Leal Denis , Claude Hattab et al.
Scientific Reports, 2018, 8, pp.11384. ⟨10.1038/s41598-018-29885-7⟩
Journal articles hal-02368694v1

A bifunctional-biased mu-opioid agonist–neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects

Armand Drieu La Rochelle , Karel Guillemyn , Maria Dumitrascuta , Charlotte Martin , Valérie Utard et al.
PAIN, 2018, 159 (9), pp.1705-1718. ⟨10.1097/j.pain.0000000000001262⟩
Journal articles hal-02368742v1

6-Endo-dig cyclization of heteroarylesters to alkynes promoted by Lewis acid catalyst in presence of Brønsted acid

Frédéric Bihel , Hellal Malik , Bourguignon Jean-Jacques
XXVII REGIO, Sep 2007, Buhl, France
Conference papers hal-00195398v1

Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new β-amyloid peptide production inhibitors and their activities on various classes of protease

Agnès Petit-Paitel , Frédéric Bihel , Gilles Quéléver , Hugues Lelouard , Agnès Petit et al.
Bioorganic and Medicinal Chemistry, 2003, 11 (14), pp.3141-3152. ⟨10.1016/s0968-0896(03)00235-9⟩
Journal articles istex hal-03016636v1
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Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies

Amandine Grimm , Imane Lejri , François Hallé , Martine Schmitt , Jürgen Götz et al.
Journal of Neuroendocrinology, 2019, ⟨10.1111/jne.12796⟩
Journal articles hal-02368671v1

Development of Dipeptidic hGPR54 Agonists

Christelle Doebelin , Isabelle I. Bertin , Séverine Schneider , Martine Schmitt , Jean-Jacques Bourguignon et al.
ChemMedChem, 2016, 11 (19), pp.2147-2154. ⟨10.1002/cmdc.201600331⟩
Journal articles istex hal-02368845v1

RF-amide neuropeptides and their receptors in Mammals: Pharmacological properties, drug development and main physiological functions

Raphaelle Quillet , Safia Ayachi , Frédéric Bihel , Khadija Elhabazi , Brigitte Ilien et al.
Alimentary Pharmacology & Therapeutics (Suppl), 2016, 160, pp.84-132. ⟨10.1016/j.pharmthera.2016.02.005⟩
Journal articles hal-02368835v1

New b-strand macrocyclic peptidomimetic analogues containing alpha-(O-, S- or NH-)aryl substituted glycine residues: synthesis, chemical and enzymatic properties

Gilles Quéléver , Frédéric Bihel , Jean-Louis Kraus
Organic & Biomolecular Chemistry, 2003, 1, pp.1676-1683
Journal articles hal-00154124v1

6-Endo-dig cyclization of heteroarylesters to alkynes promoted by Lewis acid catalyst in presence of Brønsted acid

Hellal Malik , Bourguignon Jean-Jacques , Frédéric Bihel
SAJEC, Oct 2007, Paris, France
Conference papers hal-00195387v1
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Diastereoselective Synthesis of Nonplanar 3-Amino-1,2,4-oxadiazine Scaffold: Structure Revision of Alchornedine

Shuang-Qi Tang , Maeva Leloire , Severine Schneider , Julie Mohr , Jacques Bricard et al.
Journal of Organic Chemistry, In press, ⟨10.1021/acs.joc.0c01764⟩
Journal articles hal-03021041v1

Opioid adjuvant strategy: improving opioid effectiveness

Frédéric Bihel
Future Medicinal Chemistry, 2016, 8 (3), pp.339-354. ⟨10.4155/fmc.15.186⟩
Journal articles hal-02368859v1

Discovery of Imidazoquinazolinone Derivatives as TSPO Ligands Modulating Neurosteroidogenesis and Cellular Bioenergetics in Neuroblastoma Cells Expressing Amyloid Precursor Protein

François Hallé , Imane Lejri , Mustapha Abarghaz , Amandine Grimm , Christian Klein et al.
ChemistrySelect, 2017, 2 (22), pp.6452-6457. ⟨10.1002/slct.201701565⟩
Journal articles hal-02368811v1
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Comprehensive overview of biased pharmacology at the opioid receptors: biased ligands and bias factors

Jolien de Neve , Thomas M. A. Barlow , Dirk Tourwé , Frédéric Bihel , Frédéric Simonin et al.
RSC Medicinal Chemistry, 2021, 12 (6), pp.828-870. ⟨10.1039/D1MD00041A⟩
Journal articles hal-03442028v1

The translocator protein ligand XBD173 improves clinical symptoms and neuropathological markers in the SJL/J mouse model of multiple sclerosis

I. Marginedas-Freixa , C. Hattab , G. Bouyer , F. Halle , A. Chene et al.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2017, 1863 (12), pp.3016-3027. ⟨10.1016/j.bbadis.2017.09.007⟩
Journal articles hal-02290250v1

Synthesis of 3-amino-3,4-dihydro-1H-quinolin-2-ones through regioselective palladium-catalyzed intramolecular cyclization

François Hallé , Olivier van Der Poorten , Christelle Doebelin , Marie Niederst , Séverine Schneider et al.
Tetrahedron Letters, 2016, 57 (14), pp.1547-1550. ⟨10.1016/j.tetlet.2016.02.094⟩
Journal articles hal-02290245v1
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CamKII inhibitors reduce mitotic instability, connexon anomalies and progression of the in vivo behavioral phenotype in transgenic animals expressing a mutated Gjb1 gene

Saleh Mones , Benoit Bordignon , Franck Peiretti , Jean-Francois Landrier , Burkhardt Gess et al.
Frontiers in Neuroscience, 2014, 8, 10 p. ⟨10.3389/fnins.2014.00151⟩
Journal articles hal-02639042v1

6-Endo-dig cyclization of heteroarylesters to alkynes promoted by Lewis acid catalyst in the presence of Bronsted acid

Hellal Malik , Bourguignon Jean-Jacques , Frédéric Bihel
Tetrahedron Letters, 2008, 49 (1), pp.62-65
Journal articles hal-00195333v1
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POxAP Precatalysts and the Negishi Cross-Coupling Reaction

Shuang-Qi Tang , Martine Schmitt , Frédéric Bihel
Synthesis: Journal of Synthetic Organic Chemistry, 2019, 52 (01), pp.51-59. ⟨10.1055/s-0039-1690728⟩
Journal articles hal-02997250v1
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Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation

Aline Bamia , Maha Sinane , Rima Naït-Saïdi , Jamila Dhiab , Marc Keruzoré et al.
Neurotherapeutics, 2021, 18 (2), pp.1137-1150. ⟨10.1007/s13311-020-00992-6⟩
Journal articles hal-03158577v1
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Comprehensive overview of biased pharmacology at the opioid receptors: biased ligands and bias factors

Jolien de Neve , Thomas M A Barlow , Dirk Tourwé , Frédéric Bihel , Frédéric Simonin et al.
RSC Medicinal Chemistry, 2021
Journal articles hal-03435229v1
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Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model

Maud Bollenbach , Claire Lugnier , M Elanie Kremer , Eric Salvat , Salim Megat et al.
European Journal of Medicinal Chemistry, 2019, 177, pp.269-290. ⟨10.1016/j.ejmech.2019.05.026⟩
Journal articles hal-02322399v1
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Identification of 8-Hydroxyquinoline Derivatives That Decrease Cystathionine Beta Synthase (CBS) Activity

Pierre Conan , Alice Léon , Mathilde Gourdel , Claire Rollet , Loubna Chaïr et al.
International Journal of Molecular Sciences, 2022, 23 (12), pp.6769. ⟨10.3390/ijms23126769⟩
Journal articles hal-03701324v1
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Efficient and Mild Ullmann-Type N-Arylation of Amides, Carbamates, and Azoles in Water

Maud Bollenbach , Pedro Aquino , João Xavier De araújo-Júnior , Jean-Jacques Bourguignon , Frédéric Bihel et al.
Chemistry - A European Journal, 2017, 23 (55), pp.13676-13683. ⟨10.1002/chem.201700832⟩
Journal articles hal-02368823v1
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RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents

Khadija Elhabazi , Jean-Paul Humbert , Isabelle Bertin , Raphaelle Quillet , Valérie Utard et al.
Neuropsychopharmacology, 2017, 118, pp.188-198. ⟨10.1016/j.neuropharm.2017.03.012⟩
Journal articles hal-01603852v1

Structure-activity relationship study around guanabenz identifies two derivatives retaining antiprion activity but having lost alpha 2-adrenergic receptor agonistic activity

- Phu Hai Nguyen , Hassan Hammoud , Sophie Halliez , Yanhong Pang , Justine Evrard et al.
ACS Chemical Neuroscience, 2014, 5 (10), pp.1075-1082. ⟨10.1021/cn5001588⟩
Journal articles hal-02635473v1