Search - Archive ouverte HAL Access content directly

Filter your results

13 Results
authFullName_s : Isabelle Aerts

Phase II and biomarker study of programmed cell death protein 1 inhibitor nivolumab and metronomic cyclophosphamide in paediatric relapsed/refractory solid tumours: Arm G of AcSé-ESMART, a trial of the European Innovative Therapies for Children With Cancer Consortium

Claudia Pasqualini , Jonathan Rubino , Caroline Brard , Lydie Cassard , Nicolas André et al.
European Journal of Cancer, 2021, 150, pp.53-62. ⟨10.1016/j.ejca.2021.03.032⟩
Journal articles hal-03625350v1

Impact of pharmacogenetics on variability in exposure to oral vinorelbine among pediatric patients: a model‐based population pharmacokinetic analysis

Mourad Hamimed , Pierre Leblond , Aurélie Dumont , Florence Gattacceca , Emmanuelle Tresch-Bruneel et al.
Cancer Chemotherapy and Pharmacology, 2022, 90 (1), pp.29-44. ⟨10.1007/s00280-022-04446-y⟩
Journal articles hal-03923671v1

Abstract 2022: Model-informed pediatric drug development: oral vinorelbine in low-grade glioma as a case study

Mourad Hamimed , Pierre Leblond , Aurélie Dumont , Florence Gattacceca , Emmanuelle Tresch-Bruneel et al.
AACR, Apr 2022, New Orleans (LA), United States. pp.2022-2022, ⟨10.1158/1538-7445.AM2022-2022⟩
Conference papers hal-03939634v1
Image document

Correlation between RB1germline mutations and second primary malignancies in hereditary retinoblastoma patients treated with external beam radiotherapy

Amélie Chaussade , Gaël A Millot , Constance Wells , Hervé J Brisse , Marick Laé et al.
European Journal of Medical Genetics, 2019, 62 (3), pp.217-223. ⟨10.1016/j.ejmg.2018.07.017⟩
Journal articles hal-02715581v1

Pharmacokinetics of oral vinorelbine in French children with recurrent or progressive primary low‐grade glioma

Mourad Hamimed , Florence Gattacceca , Nicolas André , Emmanuelle Tresch‐bruneel , Alicia Probst et al.
British Journal of Clinical Pharmacology, 2021, ⟨10.1111/bcp.15131⟩
Journal articles hal-03415179v1
Image document

A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

Jing Liu , Daniela Ottaviani , Meriem Sefta , Céline Desbrousses , Elodie Chapeaublanc et al.
Nature Communications, 2021, 12 (1), pp.1-20. ⟨10.1038/s41467-021-25792-0⟩
Journal articles hal-03374490v1
Image document

A Parent-of-Origin Effect Impacts the Phenotype in Low Penetrance Retinoblastoma Families Segregating the c.1981C>T/p.Arg661Trp Mutation of RB1

Philippine Eloy , Catherine Dehainault , Meriem Sefta , Isabelle Aerts , François Doz et al.
PLoS Genetics, 2016, 12 (2), pp.e1005888. ⟨10.1371/journal.pgen.1005888⟩
Journal articles hal-01286009v1

First-in-child phase I/II study of the dual mTORC1/2 inhibitor vistusertib (AZD2014) as monotherapy and in combination with topotecan-temozolomide in children with advanced malignancies: arms E and F of the AcSé-ESMART trial

Raphael J. Morscher , Caroline Brard , Pablo Berlanga , Lynley V. Marshall , Nicolas André et al.
European Journal of Cancer, 2021, 157, pp.268-277. ⟨10.1016/j.ejca.2021.08.010⟩
Journal articles hal-03487880v1

Mosaicism and prenatal diagnosis options: insights from retinoblastoma

Catherine Dehainault , Lisa Golmard , Gaël Millot , Agathe Charpin , Anthony Laugé et al.
European Journal of Human Genetics, 2017, 25 (3), pp.381-383. ⟨10.1038/ejhg.2016.174⟩
Journal articles pasteur-03105162v1

Phase I or II Study of Ribociclib in Combination With Topotecan-Temozolomide or Everolimus in Children With Advanced Malignancies: Arms A and B of the AcSé-ESMART Trial

Francisco Bautista , Xavier Paoletti , Jonathan Rubino , Caroline Brard , Keyvan Rezai et al.
Journal of Clinical Oncology, 2021, 39 (32), pp.3546-3560. ⟨10.1200/JCO.21.01152⟩
Journal articles hal-03625346v1
Image document

Metronomic Four-Drug Regimen Has Anti-tumor Activity in Pediatric Low-Grade Glioma; The Results of a Phase II Clinical Trial

Arnauld Verschuur , Marie-Amélie Heng-Maillard , Philippe Dory-Lautrec , Romain Truillet , Elisabeth Jouve et al.
Frontiers in Pharmacology, 2018, 9, pp.00950. ⟨10.3389/fphar.2018.00950⟩
Journal articles hal-02110022v1

SFCE METRO‐01 four‐drug metronomic regimen phase II trial for pediatric extracranial tumor

Marie-Amélie Heng-Maillard , Arnauld Verschuur , Audrey Aschero , Alexia Dabadie , Elisabeth Jouve et al.
Pediatric Blood and Cancer, 2019, 66 (7), pp.e27693. ⟨10.1002/pbc.27693⟩
Journal articles hal-02528441v1
Image document

Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050)☆

Nathalie Gaspar , Quentin Campbell-Hewson , Soledad Gallego Melcon , Franco Locatelli , Rajkumar Venkatramani et al.
ESMO Open, 2021, 6 (5), pp.100250. ⟨10.1016/j.esmoop.2021.100250⟩
Journal articles hal-03879123v1