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A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina
Alexis-Pierre Bemelmans
,
Sandra Duqué
,
Christel Rivière
,
Stéphanie Astord
,
Mélissa Desrosiers
et al.
Journal articles
hal-01537691v1
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Overexpression of Glutathione Peroxidase Increases the Resistance of Neuronal Cells to Aβ-Mediated Neurotoxicity
Martine Barkats
,
Stéphanie Millecamps
,
Pascale Abrioux
,
Marie-Claude Geoffroy
,
Jacques Mallet
et al.
Journal articles
hal-03083406v1
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Human alpha-Iduronidase Gene Transfer Mediated by Adeno-Associated Virus Types 1, 2, and 5 in the Brain of Nonhuman Primates: Vector Diffusion and Biodistribution
Carine Ciron
,
Arnaud Cressant
,
Françoise Roux
,
Sylvie Raoul
,
Yan Cherel
et al.
Journal articles
hal-02663855v1
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Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo.
Stéphanie Philippe
,
Chamsy Sarkis
,
Martine Barkats
,
Hamid Mammeri
,
Charline Ladroue
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (47), pp.17684-9. ⟨10.1073/pnas.0606197103⟩
Journal articles
hal-00166677v1
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SMN replacement restricted to the Central Nervous System does not rescue SMA mice.
Aurore Besse
,
Mariane Roda
,
Stéphanie Astord
,
Thibaut Marais
,
Maria Grazia Biferi
et al.
Journée des familles, Jun 2017, Paris, France
Conference poster
hal-04003309v1
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Intravenous administration of scAAV9-Hexb normalizes lifespan and prevents pathology in Sandhoff disease mice
Natalia Niemir
,
Laura Rouvière
,
Aurore Besse
,
Marie Vanier
,
Jasmin Dmytrus
et al.
Journal articles
hal-03862562v1
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Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.
Nadine Dragin
,
Jacky Bismuth
,
Géraldine Cizeron-Clairac
,
Maria Grazia Biferi
,
Claire Berthault
et al.
Journal articles
hal-01310502v1
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Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice
Martine Barkats
,
Thomas Voit
,
Aurélie Pereira de Moura
,
Stéphanie Astord
,
Romain Carcenac
et al.
Journal articles
hal-03677325v1
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β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models
Thomas Goiran
,
Eric Duplan
,
Mounia Chami
,
Alexandre Bourgeois
,
Wejdane El Manaa
et al.
Journal articles
hal-02360864v1
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1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase.
Martine Barkats
,
Philippe Horellou
,
Philippe Colin
,
Stéphanie Millecamps
,
Nicole Faucon-Biguet
et al.
Journal articles
istex
hal-00166665v1
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Neuronal transfer of the human Cu/Zn superoxide dismutase gene increases the resistance of dopaminergic neurons to 6-hydroxydopamine
Martine Barkats
,
Stéphanie Millecamps
,
Alicia Bilang-Bleuel
,
Jacques Mallet
Journal articles
hal-03220638v1
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Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons
Sandra Duqué
,
Béatrice Joussemet
,
Christel Rivière
,
Thibaut Marais
,
Laurence Dubreil
et al.
Journal articles
hal-02666576v1
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Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins
Sandro Alves
,
Thibaut Marais
,
Maria-Grazia Biferi
,
Denis Furling
,
Martina Marinello
et al.
Journal articles
hal-01371536v1
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Role of the SMN complex and the methylosome in selenoprotein mRNP assembly and translation
Anne-Sophie Gribling-Burrer
,
Hassan Hayek
,
Vincent Cura
,
Martine Barkats
,
Jean Cavarelli
et al.
11th sifrARN 2018, Nov 2018, Nancy, France
Conference papers
hal-03548946v1
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Implication of the SMN complex in the biogenesis and steady state level of the Signal Recognition Particle
Nathalie Piazzon
,
Florence Schlotter
,
Suzie Lefebvre
,
Maxime Dodre
,
Agnes Mereau
et al.
Journal articles
hal-01064047v1
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AAV9- mediated expression of SMN restricted to neurons does not rescue the spinal muscular atrophy phenotype
Piera Smeriglio
,
Aurore Besse
,
Stéphanie Astord
,
Benoit Giroux
,
Thibaut Marais
et al.
2e congrès scientifique international de SMA Europe, Feb 2020, EVRY, France
Conference poster
hal-04002484v1
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Splicing efficiency of minor introns in a mouse model of SMA predominantly depends on their branchpoint sequence and can involve the contribution of major spliceosome components
Valentin Jacquier
,
Manon Prévot
,
Thierry Gostan
,
Rémy Bordonné
,
Sofia Benkhelifa-Ziyyat
et al.
Journal articles
hal-03687098v1
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Adenoviral Retrograde Gene Transfer in Motoneurons Is Greatly Enhanced by Prior Intramuscular Inoculation with Botulinum Toxin
Stéphanie Millecamps
,
Jacques Mallet
,
Martine Barkats
Journal articles
hal-03220589v1
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Systemic AAVrh10 provides higher transgene expression than AAV9 in the brain and the spinal cord of neonatal mice
Yannick Tanguy
,
Maria Biferi
,
Aurore Besse
,
Stephanie Astord
,
Mathilde Cohen-Tannoudji
et al.
Journal articles
hal-03829252v1
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Neuron-restrictive silencer elements mediate neuron specificity of adenoviral gene expression
Stéphanie Millecamps
,
Hélène Kiefer
,
Vincent Navarro
,
Marie-Claude Geoffroy
,
Jean-Jacques Robert
et al.
Journal articles
hal-03083407v1
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SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation
Anne-Sophie Gribling-Burrer
,
Michael Leichter
,
Laurence Wurth
,
Alexandra Huttin
,
Florence Schlotter
et al.
Journal articles
hal-01541890v1
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AAV9-Mediated Expression of SMN Restricted to Neurons Does Not Rescue the Spinal Muscular Atrophy Phenotype in Mice
Aurore Besse
,
Stephanie Astord
,
Thibaut Marais
,
Marianne Roda
,
Benoit Giroux
et al.
Journal articles
inserm-03130706v1
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Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models
Inger Lauritzen
,
Anaïs Bécot
,
Alexandre Bourgeois
,
Raphaëlle Pardossi-Piquard
,
Maria-Grazia Biferi
et al.
Journal articles
hal-03001500v1
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An adenovirus encoding CuZnSOD protects cultured striatal neurones against glutamate toxicity
Martine Barkats
,
Alexis-Pierre Bemelmans
,
Marie-Claude Geoffroy
,
Jean-Jacques Robert
,
Isabelle Loquet
et al.
Journal articles
hal-03083413v1
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Efficacy and biodistribution analysis of intracerebroventricular administration of an optimized scAAV9-SMN1 vector in a mouse model of spinal muscular atrophy
Nicole Armbruster
,
Annalisa Lattanzi
,
Matthieu Jeavons
,
Laetitia van Wittenberghe
,
Bernard Gjata
et al.
Journal articles
hal-01487810v1
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Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology
Inger Lauritzen
,
Raphaëlle Pardossi-Piquard
,
Alexandre Bourgeois
,
Sophie Pagnotta
,
Maria-Grazia Biferi
et al.
Journal articles
hal-02111838v1
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AAV-mediated gene therapy for fALS
Marisa Cappella
,
Mathilde Cohen-Tannoudji
,
Thibaut Marais
,
Stéphanie Astord
,
Aurore Besse
et al.
26th ESGCT Congress, Oct 2018, Lausanne, Switzerland
Conference poster
hal-04002264v1
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