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authFullName_s : Martine Barkats
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A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina

Alexis-Pierre Bemelmans , Sandra Duqué , Christel Rivière , Stéphanie Astord , Mélissa Desrosiers et al.
PLoS ONE, 2013, 8 (4), pp.e61618. ⟨10.1371/journal.pone.0061618⟩
Journal articles hal-01537691v1

Overexpression of Glutathione Peroxidase Increases the Resistance of Neuronal Cells to Aβ-Mediated Neurotoxicity

Martine Barkats , Stéphanie Millecamps , Pascale Abrioux , Marie-Claude Geoffroy , Jacques Mallet et al.
Journal of Neurochemistry, 2000, 75 (4), pp.1438-1446. ⟨10.1046/j.1471-4159.2000.0751438.x⟩
Journal articles hal-03083406v1

Human alpha-Iduronidase Gene Transfer Mediated by Adeno-Associated Virus Types 1, 2, and 5 in the Brain of Nonhuman Primates: Vector Diffusion and Biodistribution

Carine Ciron , Arnaud Cressant , Françoise Roux , Sylvie Raoul , Yan Cherel et al.
Human Gene Therapy, 2009, 20 (4), pp.350-360. ⟨10.1089/hum.2008.155⟩
Journal articles hal-02663855v1

Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo.

Stéphanie Philippe , Chamsy Sarkis , Martine Barkats , Hamid Mammeri , Charline Ladroue et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (47), pp.17684-9. ⟨10.1073/pnas.0606197103⟩
Journal articles hal-00166677v1

SMN replacement restricted to the Central Nervous System does not rescue SMA mice.

Aurore Besse , Mariane Roda , Stéphanie Astord , Thibaut Marais , Maria Grazia Biferi et al.
Journée des familles, Jun 2017, Paris, France
Conference poster hal-04003309v1

Intravenous administration of scAAV9-Hexb normalizes lifespan and prevents pathology in Sandhoff disease mice

Natalia Niemir , Laura Rouvière , Aurore Besse , Marie Vanier , Jasmin Dmytrus et al.
Human Molecular Genetics, 2018, 27 (6), pp.954-968. ⟨10.1093/hmg/ddy012⟩
Journal articles hal-03862562v1
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Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.

Nadine Dragin , Jacky Bismuth , Géraldine Cizeron-Clairac , Maria Grazia Biferi , Claire Berthault et al.
Journal of Clinical Investigation, 2016, 126 (4), pp.1525-37. ⟨10.1172/JCI81894⟩
Journal articles hal-01310502v1

Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice

Martine Barkats , Thomas Voit , Aurélie Pereira de Moura , Stéphanie Astord , Romain Carcenac et al.
Human Molecular Genetics, 2011, 20 (4), pp.681-693. ⟨10.1093/hmg/ddq514⟩
Journal articles hal-03677325v1
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β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models

Thomas Goiran , Eric Duplan , Mounia Chami , Alexandre Bourgeois , Wejdane El Manaa et al.
Biological Psychiatry, 2018, 83 (5), pp.416-427. ⟨10.1016/j.biopsych.2017.04.011⟩
Journal articles hal-02360864v1

1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase.

Martine Barkats , Philippe Horellou , Philippe Colin , Stéphanie Millecamps , Nicole Faucon-Biguet et al.
Journal of Neuroscience Research, 2006, 83 (2), pp.233-42. ⟨10.1002/jnr.20696⟩
Journal articles istex hal-00166665v1

Neuronal transfer of the human Cu/Zn superoxide dismutase gene increases the resistance of dopaminergic neurons to 6-hydroxydopamine

Martine Barkats , Stéphanie Millecamps , Alicia Bilang-Bleuel , Jacques Mallet
Journal of Neurochemistry, 2002, 82 (1), pp.101-109. ⟨10.1046/j.1471-4159.2002.00952.x⟩
Journal articles hal-03220638v1

Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons

Sandra Duqué , Béatrice Joussemet , Christel Rivière , Thibaut Marais , Laurence Dubreil et al.
Molecular Therapy, 2009, 17 (7), pp.1187-1196. ⟨10.1038/mt.2009.71⟩
Journal articles hal-02666576v1
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Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins

Sandro Alves , Thibaut Marais , Maria-Grazia Biferi , Denis Furling , Martina Marinello et al.
Molecular Neurodegeneration, 2016, 11, pp.58. ⟨10.1186/s13024-016-0123-2⟩
Journal articles hal-01371536v1
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Role of the SMN complex and the methylosome in selenoprotein mRNP assembly and translation

Anne-Sophie Gribling-Burrer , Hassan Hayek , Vincent Cura , Martine Barkats , Jean Cavarelli et al.
11th sifrARN 2018, Nov 2018, Nancy, France
Conference papers hal-03548946v1
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Implication of the SMN complex in the biogenesis and steady state level of the Signal Recognition Particle

Nathalie Piazzon , Florence Schlotter , Suzie Lefebvre , Maxime Dodre , Agnes Mereau et al.
Nucleic Acids Research, 2013, 41 (2), pp.1255-1272. ⟨10.1093/nar/gks1224⟩
Journal articles hal-01064047v1

AAV9- mediated expression of SMN restricted to neurons does not rescue the spinal muscular atrophy phenotype

Piera Smeriglio , Aurore Besse , Stéphanie Astord , Benoit Giroux , Thibaut Marais et al.
2e congrès scientifique international de SMA Europe, Feb 2020, EVRY, France
Conference poster hal-04002484v1
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Splicing efficiency of minor introns in a mouse model of SMA predominantly depends on their branchpoint sequence and can involve the contribution of major spliceosome components

Valentin Jacquier , Manon Prévot , Thierry Gostan , Rémy Bordonné , Sofia Benkhelifa-Ziyyat et al.
RNA, 2022, 28 (3), pp.303-319. ⟨10.1261/rna.078329.120⟩
Journal articles hal-03687098v1

Adenoviral Retrograde Gene Transfer in Motoneurons Is Greatly Enhanced by Prior Intramuscular Inoculation with Botulinum Toxin

Stéphanie Millecamps , Jacques Mallet , Martine Barkats
Human Gene Therapy, 2002, 13 (2), pp.225-232. ⟨10.1089/10430340252769752⟩
Journal articles hal-03220589v1

Systemic AAVrh10 provides higher transgene expression than AAV9 in the brain and the spinal cord of neonatal mice

Yannick Tanguy , Maria Biferi , Aurore Besse , Stephanie Astord , Mathilde Cohen-Tannoudji et al.
Frontiers in Molecular Neuroscience, 2015, 8, ⟨10.3389/fnmol.2015.00036⟩
Journal articles hal-03829252v1

Neuron-restrictive silencer elements mediate neuron specificity of adenoviral gene expression

Stéphanie Millecamps , Hélène Kiefer , Vincent Navarro , Marie-Claude Geoffroy , Jean-Jacques Robert et al.
Nature Biotechnology, 1999, 17 (9), pp.865-869. ⟨10.1038/12849⟩
Journal articles hal-03083407v1
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SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation

Anne-Sophie Gribling-Burrer , Michael Leichter , Laurence Wurth , Alexandra Huttin , Florence Schlotter et al.
Nucleic Acids Research, 2017, 45 (9), pp.5399-5413. ⟨10.1093/nar/gkx031⟩
Journal articles hal-01541890v1
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AAV9-Mediated Expression of SMN Restricted to Neurons Does Not Rescue the Spinal Muscular Atrophy Phenotype in Mice

Aurore Besse , Stephanie Astord , Thibaut Marais , Marianne Roda , Benoit Giroux et al.
Molecular Therapy, 2020, 28 (8), pp.1887-1901. ⟨10.1016/j.ymthe.2020.05.011⟩
Journal articles inserm-03130706v1
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Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models

Inger Lauritzen , Anaïs Bécot , Alexandre Bourgeois , Raphaëlle Pardossi-Piquard , Maria-Grazia Biferi et al.
Translational Neurodegeneration, 2019, 8, ⟨10.1186/s40035-019-0176-6⟩
Journal articles hal-03001500v1

An adenovirus encoding CuZnSOD protects cultured striatal neurones against glutamate toxicity

Martine Barkats , Alexis-Pierre Bemelmans , Marie-Claude Geoffroy , Jean-Jacques Robert , Isabelle Loquet et al.
NeuroReport, 1996, 7 (2), pp.497-501. ⟨10.1097/00001756-199601310-00029⟩
Journal articles hal-03083413v1
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Efficacy and biodistribution analysis of intracerebroventricular administration of an optimized scAAV9-SMN1 vector in a mouse model of spinal muscular atrophy

Nicole Armbruster , Annalisa Lattanzi , Matthieu Jeavons , Laetitia van Wittenberghe , Bernard Gjata et al.
Molecular Therapy - Methods and Clinical Development, 2016, 3, pp.UNSP 16060. ⟨10.1038/mtm.2016.60⟩
Journal articles hal-01487810v1

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology

Inger Lauritzen , Raphaëlle Pardossi-Piquard , Alexandre Bourgeois , Sophie Pagnotta , Maria-Grazia Biferi et al.
Acta Neuropathologica, 2016, 132 (2), pp.257 - 276. ⟨10.1007/s00401-016-1577-6⟩
Journal articles hal-02111838v1

AAV-mediated gene therapy for fALS

Marisa Cappella , Mathilde Cohen-Tannoudji , Thibaut Marais , Stéphanie Astord , Aurore Besse et al.
26th ESGCT Congress, Oct 2018, Lausanne, Switzerland
Conference poster hal-04002264v1