Search - Archive ouverte HAL Access content directly

Filter your results

40 Results
authFullName_s : Nathalie Vergnolle
Image document

The INSPIRE bio-resource research platform for healthy aging and geroscience: focus on the human translational research cohort (the INSPIRE-t cohort)

Sophie Guyonnet , Yves Rolland , C Takeda , P.-J Ousset , I. Ader et al.
The Journal of Frailty & Aging, In press, 10 (2), pp.110-120. ⟨10.14283/jfa.2020.38⟩
Journal articles hal-03023578v1
Image document

Towards a Large-Scale Assessment of the Relationship Between Biological and Chronological Aging

Yohan Santin , Sébastien Lopez , Isabelle Ader , Sandrine Andrieu , Nicolas Blanchard et al.
The Journal of Frailty & Aging, 2020, 10 (2), pp.121-131. ⟨10.14283/jfa.2020.43⟩
Journal articles inserm-03019973v1
Image document

Healthy Aging Biomarkers: The INSPIRE's Contribution

Nathalie Vergnolle , Isabelle Ader , Luc Penicaud , Isabelle Raymond Letron , Sandrine Andrieu et al.
The Journal of Frailty & Aging, 2021, ⟨10.14283/jfa.2021.15⟩
Journal articles hal-03320578v1

L’être vivant dans son environnement

Samuel Alizon , F. Angelier , Guillaume Bécard , Laurent Bezin , F Courchamp et al.
CNRS Editions. Etonnant vivant. Découvertes et promesses du XXIème siècle (Livre blanc)., 2017
Book sections hal-01923240v1
Image document

Functional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease

Alexandre Denadai-Souza , Chrystelle Bonnart , Núria Solà Tapias , Marlène Marcellin , Brendan Gilmore et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-26282-y⟩
Journal articles hal-02179482v1
Image document

Human enteric glial cells are defective for 15-HETE production and epithelial permeability control in Crohn’s disease

Camille Pochard , Sabrina Coquenlorge , Julie Jaulin , Nicolas Cenac , Nathalie Vergnolle et al.
Gastroenterology, 2016, 150 (1), pp.168-180. ⟨10.1053/j.gastro.2015.09.038⟩
Journal articles hal-03153620v1
Image document

Oral administration of recombinant lactic acid bacteria delivering antiproteases at the mucosal level protects mice from colitis

L.L. Martin , Jean-Paul Motta , Luis L. Bermudez Humaran , Pascale P. Kharrat , J. -M. J. -M. Sallenave et al.
10. World Congress on Inflammation, Jun 2011, Paris, France. pp.S80, ⟨10.1007/s00011-011-0341-6⟩
Conference papers hal-01001507v1

Apelin targets gut contraction to control glucose metabolism via the brain

Audren Fournel , Anne Drougard , Thibaut Duparc , Alysson Marlin , Stuart Brierley et al.
Gut, 2017, 66 (2), pp.258-269. ⟨10.1136/gutjnl-2015-310230⟩
Journal articles hal-02393155v1
Image document

Serine protease inhibitors protect better than IL-10 and TGF-beta anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci

Luis Bermudez Humaran , Jean-Paul Motta , Camille Aubry , Pascale Kharrat , Laurence Rous-Martin et al.
Microbial Cell Factories, 2015, 14, ⟨10.1186/s12934-015-0198-4⟩
Journal articles hal-01204481v1

Engineering lactococci and lactobacilli for human health

Luis Bermúdez-Humarán , Camille Aubry , Jean-Paul Motta , Céline Deraison , Lothar Steidler et al.
Current Opinion in Microbiology, 2013, 16 (3), pp.278-283. ⟨10.1016/j.mib.2013.06.002⟩
Journal articles hal-01003315v1
Image document

The arachidonic acid metabolite 11β-ProstaglandinF2α controls intestinal epithelial healing: deficiency in patients with Crohn's disease

Sabrina Coquenlorge , Laurianne van Landeghem , Julie Jaulin , Nicolas Cenac , Nathalie Vergnolle et al.
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep25203⟩
Journal articles hal-03153609v1
Image document

Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium

Eloïse Mussard , Cécile Pouzet , Virginie Helies , Géraldine Pascal , Sandra Fourre et al.
Stem Cell Research, 2020, 48, pp.1-10. ⟨10.1016/j.scr.2020.101980⟩
Journal articles hal-02983697v1
Image document

Endogenous analgesia mediated by CD4+ T lymphocytes is dependent on enkephalins in mice

Lilian Basso , Jérôme Boué , Karim Mahiddine , Catherine Blanpied , Sébastien Robiou-Du-Pont et al.
Journal of Neuroinflammation, 2016, 13 (1), pp.132. ⟨10.1186/s12974-016-0591-x⟩
Journal articles inserm-01324419v1
Image document

Modifying the Protease, Antiprotease Pattern by Elafin Overexpression Protects Mice From Colitis

Jean-Paul Motta* , Laurent Magne* , Delphyne Descamps , Corinne Rolland , Camila Squarzoni-Dale et al.
Gastroenterology, 2010, 140 (4), pp.1272-82. ⟨10.1053/j.gastro.2010.12.050⟩
Journal articles pasteur-00552947v1

The Inspire Research Initiative: A Program for Geroscience and Healthy Aging Research going from Animal Models to Humans and the Healthcare System

Philippe Barreto de Souto , Sophie Guyonnet , Isabelle Ader , Sandrine Andrieu , Louis Casteilla et al.
The Journal of Frailty & Aging, In press, 10 (2), pp.86-93. ⟨10.14283/jfa.2020.18⟩
Journal articles hal-02899807v1
Image document

Thrombin modifies growth, proliferation and apoptosis of human colon organoids: a protease-activated receptor 1- and protease-activated receptor 4-dependent mechanism

Morgane Sébert , Alexandre Denadai-Souza , Muriel Quaranta , Claire Racaud-Sultan , Sophie Chabot et al.
British Journal of Pharmacology, 2018, 175 (18), pp.3656-3668. ⟨10.1111/bph.14430⟩
Journal articles hal-02332340v1
Image document

Revisiting the Hallmarks of Aging to Identify Markers of Biological Age.

Florent Guerville , P. de Souto Barreto , I. Ader , S. Andrieu , L. Casteilla et al.
The Journal of prevention of Alzheimer's disease, 2020, 7 (1), pp.56-64. ⟨10.14283/jpad.2019.50⟩
Journal articles hal-02628293v1

Protective role for Protease-Activated-Receptor-2 against Influenza virus Pathogenesis via an Interferon-Y dependent pathway

Khaled Khoufache , Fanny Le Bouder , Eric E. Morello , Fabrice Laurent , Sabine Riffault et al.
Journées d'animation scientifique du Département Santé Animale, May 2009, Port d'Albret, France
Conference papers hal-02755857v1

Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered wnt signaling.

Mathieu Despeaux , Gaëtan Chicanne , Evelyne Rouer , Fabienne de Toni , Jessica Bertrand et al.
Stem Cells / Stem Cells (Miamisburg), 2012, 30 (8), pp.1597-610. ⟨10.1002/stem.1157⟩
Journal articles inserm-00726849v1

Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs)

K. Oikonomopoulou , K. K. Hansen , M. Saifeddine , Nathalie Vergnolle , I. Tea et al.
Biological Chemistry, 2006, 387, pp.817-824
Journal articles hal-00320919v1

Inhibition of sensory afferents activation and visceral pain by a brominated algal diterpene.

R. Chatter , Nicolas Cenac , V. Roussis , R. Kharrat , Nathalie Vergnolle et al.
Neurogastroenterology & Motility, 2012, 24 (7), pp.e336-43. ⟨10.1111/j.1365-2982.2012.01940.x⟩
Journal articles istex pasteur-00862463v1

Colitis Linked to Endoplasmic Reticulum Stress Induces Trypsin Activity Affecting Epithelial Functions

Núria Solà Tapias , Alexandre Denadai-Souza , Claire Rolland-Fourcade , Muriel Quaranta-Nicaise , Catherine Blanpied et al.
Journal of Crohn's and Colitis, 2021, 15 (9), pp.1528-1541. ⟨10.1093/ecco-jcc/jjab035⟩
Journal articles hal-03510555v1
Image document

Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection

Thomas Gobbetti , Jesmond Dalli , Romain A. Colas , Donata Federici Canova , Marius Aursnes et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (15), pp.3963-3968. ⟨10.1073/pnas.1617290114⟩
Journal articles hal-01604739v1
Image document

TRPV4: new therapeutic target for inflammatory bowel diseases.

Nathalie Vergnolle
Biochemical Pharmacology, 2014, 89 (2), pp.157-61. ⟨10.1016/j.bcp.2014.01.005⟩
Journal articles inserm-00975985v1

Novel role of the serine protease inhibitor elafin in gluten-related disorders

Heather J Galipeau , Michelle Wiepjes , Jean-Paul Motta , Jessica D Schulz , Jennifer Jury et al.
The American Journal of Gastroenterology, 2014, 109 (5), pp.748-56. ⟨10.1038/ajg.2014.48⟩
Journal articles hal-01204309v1

Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

Jean-Paul Motta , Luis Bermudez Humaran , Céline Deraison , Laurence Martin , Corinne Rolland et al.
Science Translational Medicine, 2012, 4 (158), ⟨10.1126/scitranslmed.3004212⟩
Journal articles hal-01204261v1

Using murine colitis models to analyze probiotics–host interactions

Rebeca Martin Rosique , Florian Chain , Sylvie Miquel , Jean-Paul Motta , Nathalie Vergnolle et al.
FEMS Microbiology Reviews, 2017, 41 (Supp_1), pp.S49-S70. ⟨10.1093/femsre/fux035⟩
Journal articles hal-01602302v1
Image document

Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study

Alexandre Denadai-Souza , Camilla Moreira Ribeiro , Corinne Rolland , Anne Thouard , Céline Deraison et al.
Arthritis Research and Therapy, 2016, 19 (1), pp.124. ⟨10.1186/s13075-017-1326-9⟩
Journal articles inserm-01536348v1

Mucosal targeting of therapeutic molecules using genetically modified lactic acid bacteria: an update

Jean Guy Leblanc , Camille Aubry , Naima Bermudez , Alejandra de Moreno de Leblanc , Nathalie Vergnolle et al.
FEMS Microbiology Letters, 2013, 344 (1), pp.1 - 9. ⟨10.1111/1574-6968.12159⟩
Journal articles hal-01019086v1
Image document

Colon-specific immune microenvironment regulates cancer progression versus rejection

Giulia Trimaglio , Anne-Françoise Tilkin-Mariamé , Virginie Feliu , Françoise Lauzéral-Vizcaino , Marie Tosolini et al.
OncoImmunology, 2020, 9 (1), pp.1-12. ⟨10.1080/2162402X.2020.1790125⟩
Journal articles hal-03000701v1