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authFullName_s : Nicolas Gadot

DCC constrains tumour progression via its dependence receptor activity.

Marie Castets , Laura Broutier , Yann Molin , Marie Brevet , Guillaume Chazot et al.
Nature, 2012, 482 (7386), pp.534-7. ⟨10.1038/nature10708⟩
Journal articles istex inserm-00721045v1

Longitudinal assessment of PD-L1 expression and gene expression profiles in patients with head and neck cancer reveals temporal heterogeneity

Andy Karabajakian , Jebrane Bouaoud , Lucas Michon , Maud Kamal , Carole Crozes et al.
Oral Oncology, 2021, 119, pp.105368. ⟨10.1016/j.oraloncology.2021.105368⟩
Journal articles hal-03865051v1
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A minimal standardized human bone marrow microphysiological system to assess resident cell behavior during normal and pathological processes

Thibault Voeltzel , Gaëlle Fossard , Michaël Degaud , Kevin Geistlich , Nicolas Gadot et al.
Biomaterials Science, 2022, 10 (2), pp.485-498. ⟨10.1039/d1bm01098k⟩
Journal articles hal-03758030v1

Histopathological changes induced by selective inactivation of menin on the thyroid gland in RET/PTC3 and E7 transgenic mice. A study of 77 cases

Oana-Maria Capraru , Nicole Berger , Nicolas Gadot , Myriam Decaussin-Petrucci , Chang Zhang et al.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2016, 57, pp.91-98
Journal articles hal-01792385v1

Targeting netrin-1/DCC interaction in diffuse large B-cell and mantle cell lymphomas

Laura Broutier , Marion Creveaux , Jonathan Vial , Antonin Tortereau , Jean-Guy Delcros et al.
EMBO Molecular Medicine, 2016, 8 (2), pp.96--104. ⟨10.15252/emmm.201505480⟩
Journal articles hal-01269905v1

Men1 disruption in Nkx3.1-deficient mice results in ARlow/CD44+ microinvasive carcinoma development with the dysregulated AR pathway

Romain Teinturier , Yakun Luo , Myriam Decaussin-Petrucci , Virginie Vlaeminck-Guillem , Francis Vacherot et al.
Oncogene, 2021, 40 (6), pp.1118-1127. ⟨10.1038/s41388-020-01589-1⟩
Journal articles hal-03666659v1

Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies.

Agnès Bernet , Laetitia Mazelin , Marie-May Coissieux , Nicolas Gadot , Susan L Ackerman et al.
Gastroenterology, 2007, 133 (6), pp.1840-8. ⟨10.1053/j.gastro.2007.08.009⟩
Journal articles hal-00475912v1
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Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling

Luiz W. Ribeiro , Mathé Pietri , Hector Ardila-Osorio , Anne Baudry , François Boudet-Devaud et al.
Particle and Fibre Toxicology, 2022, 19 (1), pp.48. ⟨10.1186/s12989-022-00490-x⟩
Journal articles anses-03736622v1

Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis

Pierre-Antoine Bissey , Pauline Mathot , Catherine Guix , Mélissa Jasmin , Isabelle Goddard et al.
Cancer Research, 2020, 80 (10), pp.1970-1980. ⟨10.1158/0008-5472.CAN-19-1340⟩
Journal articles hal-03102147v1

Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance

Duygu Ozmadenci , Olivier Féraud , Suzy S. Markossian , Elsa Kress , Benjamin Ducarouge et al.
Nature Communications, 2015, 6 (1), ⟨10.1038/ncomms8398⟩
Journal articles hal-02463301v1

Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer

Sandra Ortiz-Cuaran , Aurélie Swalduz , Jean-Philippe Foy , Solène Marteau , Anne-Pierre Morel et al.
European Journal of Cancer, 2022, 169, pp.106-122. ⟨10.1016/j.ejca.2022.03.038⟩
Journal articles hal-04030585v1

Netrin-1 and Its Receptor DCC Are Causally Implicated in Melanoma Progression

Amina Boussouar , Antonin Tortereau , Ambroise Manceau , Andrea Paradisi , Nicolas Gadot et al.
Cancer Research, 2020, 80 (4), pp.747-756. ⟨10.1158/0008-5472.CAN-18-1590⟩
Journal articles hal-02493700v1

Mechanisms of local invasion in enteroendocrine tumors: Identification of novel candidate cytoskeleton-associated proteins in an experimental mouse model by a proteomic approach and validation in human tumors

Christophe Couderc , Julien Bollard , Yohann Couté , Patrick Massoma , Gilles Poncet et al.
Molecular and Cellular Endocrinology, 2015, 399, pp.154-163. ⟨10.1016/j.mce.2014.09.006⟩
Journal articles hal-02135101v1
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The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade

P. Foy , Chloé Bertolus , Marie-Cécile Michallet , Sophie Deneuve , R. Incitti et al.
Annals of Oncology, 2017, 28 (8), pp.1934-1941. ⟨10.1093/annonc/mdx210⟩
Journal articles hal-01560943v1

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma

Andy Karabajakian , Thibaut Garrivier , Carole Crozes , Nicolas Gadot , Jean-Yves Blay et al.
Oncotarget, 2020, 11 (18), pp.1618-1628. ⟨10.18632/oncotarget.27563⟩
Journal articles hal-03851743v1

Targeting the PI3K/mTOR pathway in murine endocrine cell lines: in vitro and in vivo effects on tumor cell growth.

Christophe Couderc , Gilles Poncet , Karine Villaume , Martine Blanc , Nicolas Gadot et al.
American Journal of Pathology, 2011, 178 (1), pp.336-44. ⟨10.1016/j.ajpath.2010.11.023⟩
Journal articles hal-00710288v1
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Hepatitis D virus interferes with hepatitis B virus RNA production via interferon-dependent and -independent mechanisms

Julie Lucifora , Dulce Alfaiate , Caroline Pons , Maud Michelet , Ricardo Ramirez et al.
Journal of Hepatology, In press, ⟨10.1016/j.jhep.2023.01.005⟩
Journal articles hal-03992721v1
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Targeting netrin‐3 in small cell lung cancer and neuroblastoma

Shan Jiang , Mathieu Richaud , Pauline Vieugué , Nicolas Rama , Jean‐guy Delcros et al.
EMBO Molecular Medicine, 2021, 13 (4), ⟨10.15252/emmm.202012878⟩
Journal articles hal-03410529v1
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Fusion-negative Rhabdomyosarcoma 3D-organoids as an innovative model to predict resistance to cell death inducers

Clara Savary , Paul Huchedé , Léa Luciana , Arthur Tourbez , Clémence Deligne et al.
Preprints, Working Papers, ... hal-03797992v1
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Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression

Andrea Paradisi , Carine Maisse-Paradisi , Marie-May Coissieux , Nicolas Gadot , Florian Lépinasse et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (40), pp.17146-17151. ⟨10.1073/pnas.0901767106⟩
Journal articles hal-01604345v1

Cooperation Between the Thyroid Hormone Receptor TR alpha 1 and the WNT Pathway in the Induction of Intestinal Tumorigenesis

Elsa Kress , Seham Skah , Maria Sirakov , Julien Nadjar , Nicolas Gadot et al.
Gastroenterology, 2010, 138 (5), pp.1863-1874. ⟨10.1053/j.gastro.2010.01.041⟩
Journal articles hal-02660075v1
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Low glucose microenvironment of normal kidney cells stabilizes a subset of messengers involved in angiogenesis

Elodie de Laplanche , Asma Boudria , Estelle Dacheux , Anne Vincent , Nicolas Gadot et al.
Physiological Reports, 2015, 3 (1), pp.e12253. ⟨10.14814/phy2.12253⟩
Journal articles inserm-02337370v1

Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling

Aurélia Huyghe , Giacomo Furlan , Duygu Ozmadenci , Christina Galonska , Jocelyn Charlton et al.
Nature Cell Biology, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Journal articles hal-03102136v1

Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRAS G12D -driven Pancreatic Tumorigenesis

Nicolas Chuvin , David Vincent , Roxane Pommier , Lindsay B Alcaraz , Johann Gout et al.
Cellular and Molecular Gastroenterology and Hepatology, 2017, 4 (2), pp.263-282. ⟨10.1016/j.jcmgh.2017.05.005⟩
Journal articles hal-02284709v1

Intratumoural spatial distribution of S100B + folliculostellate cells is associated with proliferation and expression of FSH and ERα in gonadotroph tumours

Mirela Diana Ilie , Alexandre Vasiljevic , Marie Chanal , Nicolas Gadot , Laura Chinezu et al.
Acta Neuropathologica Communications, 2022, 10 (1), pp.18. ⟨10.1186/s40478-022-01321-y⟩
Journal articles hal-03666692v1
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Early changes in the immune microenvironment of oral potentially malignant disorders reveal an unexpected association of M2 macrophages with oral cancer free survival

Jebrane Bouaoud , Jean-Philippe Foy , Antonin Tortereau , Lucas Michon , Vincent Lavergne et al.
OncoImmunology, 2021, 10 (1), pp.1944554. ⟨10.1080/2162402x.2021.1944554⟩
Journal articles hal-03282364v1
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Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity

Céline Delloye-Bourgeois , Benjamin Gibert , Nicolas Rama , Jean-Guy Delcros , Nicolas Gadot et al.
PLoS Biology, 2013, 11 (8), pp.e1001623. ⟨10.1371/journal.pbio.1001623⟩
Journal articles inserm-02130094v1

Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation

Diana Farhat , Sophie Léon , Sandra Ghayad , Nicolas Gadot , Philippe Icard et al.
British Journal of Cancer, 2020, 122 (6), pp.885-894. ⟨10.1038/s41416-020-0729-6⟩
Journal articles hal-03869488v1