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authFullName_s : Philippe Moullier

Chem-AAV: Chemically Modified AAV for Gene Therapy

Mathieu Mevel , Mohammed Bouzelha , Laurence Dubreil , Estelle Toublanc , Veronique Blouin et al.
20th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy, 2017, NA, France. pp.1
Conference papers hal-01600854v1

La génétique, science humaine

Muriel Fabre Magnan , Philippe Moullier
Belin, 303 p., 2004
Books hal-00425206v1

Off-Target Analysis of a rAAV-U7snRNA Vector Used for the Treatment of Duchenne Patients By Exon Skipping

Claire Domenger , Aurélie Lardenois , Marine Allais , Virginie Francois , Marie Montus et al.
18. Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), American Society of Cell and Gene Therapy (ASGCT). Milwaukee, USA., May 2015, Nouvelle Orléans, United States. pp.1
Conference papers hal-02740856v1

Saut d’exon par AAV8/U7 dans la dystrophie musculaire de Duchenne : De la souris à l’homme en passant par le chien

Laurent Servais , Caroline Le Guiner , Marie Montus , Luis Garcia , Yves Fromes et al.
XXIIème congrès de la SFNP, Société Française de Neurologie Pédiatrique (SFNP). FRA., Jan 2012, Marseille, France
Conference papers hal-02804793v1

Human alpha-Iduronidase Gene Transfer Mediated by Adeno-Associated Virus Types 1, 2, and 5 in the Brain of Nonhuman Primates: Vector Diffusion and Biodistribution

Carine Ciron , Arnaud Cressant , Françoise Roux , Sylvie Raoul , Yan Cherel et al.
Human Gene Therapy, 2009, 20 (4), pp.350-360. ⟨10.1089/hum.2008.155⟩
Journal articles hal-02663855v1
Image document

Chemical modification of the adeno-associated virus capsid to improve gene delivery

Mathieu Mével , Mohammed Bouzelha , Aurélien Leray , Simon Pacouret , Mickaël Guilbaud et al.
Chemical Science, 2020, 11 (4), pp.1122-1131. ⟨10.1039/C9SC04189C⟩
Journal articles inserm-02451454v1
Image document

Effective Limb Transduction and Phenotypic Correction after Injection of rAAV8-U7 snRNA in GRMD Dogs

Caroline Le Guiner , Marie Montus , Laurent Servais , Luis Garcia , Yves Fromes et al.
ASGCT Translational Science Training Course, American Society of Cell and Gene Therapy (ASGCT). USA., Mar 2011, Seattle, United States. pp.332
Conference papers hal-01191233v1
Image document

Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing

Emilie Lecomte , Benoit Tournaire , Benjamin Cogné , Jean-Baptiste Dupont , Pierre Lindenbaum et al.
Molecular Therapy - Nucleic Acids, 2015, 4, pp.e260. ⟨10.1038/mtna.2015.32⟩
Journal articles inserm-01799968v1
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Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy

Caroline C. Le Guiner , Laurent Servais , Marie Montus , Thibaut Thibaut , Bodvael Fraysse et al.
Nature Communications, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Journal articles hal-02179396v1

Gene Therapy Prolongs Survival and Restores Function in Murine and Canine Models of Myotubular Myopathy

Martin Childers , Romain Joubert , Karine Poulard , Christel Moal , Robert Grange et al.
Science Translational Medicine, 2014, 6 (220), pp.220ra10-220ra10. ⟨10.1126/scitranslmed.3007523⟩
Journal articles hal-02180848v1

Characterization of Producer Cell-Dependent Restriction of Murine Leukemia Virus Replication

Fatima Serhan , Nathalie Jourdan , Sylvie Saleun , Philippe Moullier , Ghislaine Duisit et al.
Journal of Virology, 2002, 76 (13), pp.6609-6617. ⟨10.1128/jvi.76.13.6609-6617.2002⟩
Journal articles hal-03975585v1
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Mannose-coupled AAV2: a second generation AAV vector for increased retinal gene therapy efficiency

Mathieu Mével , Virginie Pichard , Mohammed Bouzelha , Dimitri Alvarez-Dorta , Pierre-Alban Lalys et al.
2022
Preprints, Working Papers, ... hal-03860614v1

Successful Gene Therapy in the RPGRIP1-deficient Dog: a Large Model of Cone-Rod Dystrophy.

Elsa Lhériteau , Lolita Petit , Michel Weber , Guylène Le Meur , Jack-Yves Deschamps et al.
Molecular Therapy, 2014, 22 (2), pp.265-77. ⟨10.1038/mt.2013.232⟩
Journal articles hal-00957330v1

In Vivo Delivery of Human α - l -Iduronidase in Mice Implanted with Neo-Organs

Anna Salvetti , Philippe Moullier , Véronique Cornet , Doug Brooks , John Hopwood et al.
Human Gene Therapy, 1995, 6 (9), pp.1153-1159. ⟨10.1089/hum.1995.6.9-1153⟩
Journal articles hal-03330129v1

Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis

Guylène Le Meur , Pierre Lebranchu , Fanny Billaud , Oumeya Adjali , Sébastien Schmitt et al.
Molecular Therapy, 2018, 26 (1), pp.256 - 268. ⟨10.1016/j.ymthe.2017.09.014⟩
Journal articles inserm-01785885v1
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Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8 + T Cells in Human Donors Allows the Detection of a T EMRA Subpopulation

Celine Vandamme , Rebecca Xicluna , Leslie Hesnard , Marie Devaux , Nicolas Jaulin et al.
Frontiers in Immunology, 2020, 10, pp.3110. ⟨10.3389/fimmu.2019.03110⟩
Journal articles inserm-02447186v1

Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts.

Nathalie Cartier , Jacqueline Lopez , Philippe Moullier , Francis Rocchiccioli , Marie-Odile Rolland et al.
Proceedings of the National Academy of Sciences of the United States of America, 1995, 92 (5), pp.1674-1678. ⟨10.1073/pnas.92.5.1674⟩
Journal articles hal-03834875v1

Delivery of therapeutic proteins from genetically-modified cells

Nadia Naffakh , Philippe Moullier , Anna Salvetti , Delphine Bohl , Olivier Danos et al.
Restorative Neurology and Neuroscience, 1995, 8 (1,2), pp.67-69. ⟨10.3233/RNN-1995-81216⟩
Journal articles hal-03330125v1

Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons

Sandra Duqué , Béatrice Joussemet , Christel Rivière , Thibaut Marais , Laurence Dubreil et al.
Molecular Therapy, 2009, 17 (7), pp.1187-1196. ⟨10.1038/mt.2009.71⟩
Journal articles hal-02666576v1

Accurate Identification and Quantification of DNA Species by Next Generation Sequencing in Adeno-Associated Viral Vectors Produced in Insect Cells

Magalie Penaud-Budloo , Emilie Lecomte , Aurélien Guy-Duché , Sylvie Saleun , Alain Roulet et al.
20. Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), May 2017, Washington, United States
Conference papers hal-01607265v1

Forelimb Treatment in a Large Cohort of Dystrophic Dogs Supports Delivery of a Recombinant AAV for Exon Skipping in Duchenne Patients

Caroline Le Guiner , Marie Montus , Laurent Servais , Yan Cherel , Virginie François et al.
Molecular Therapy, 2014, 22 (11), pp.1923-1935. ⟨10.1038/mt.2014.151⟩
Journal articles inserm-02447482v1
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Accurate Identification and Quantification of DNA Species by Next-Generation Sequencing in Adeno-Associated Viral Vectors Produced in Insect Cells

Magalie Penaud-Budloo , Emilie Lecomte , Aurélien Guy-Duché , Sylvie Saleun , Alain Roulet et al.
Human gene therapy methods, 2017, 28 (3), pp.148-162. ⟨10.1089/hgtb.2016.185⟩
Journal articles hal-01608396v1
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Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA

Jean-Baptiste Dupont , Benoit Tournaire , Christophe Georger , Béatrice Marolleau , Laurence Jeanson-Leh et al.
Molecular Therapy - Methods and Clinical Development, 2015, 27 (3), pp.122-34. ⟨10.1038/mtm.2015.10⟩
Journal articles inserm-01799048v1
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Vitrectomy Before Intravitreal Injection of AAV2/2 Vector Promotes Efficient Transduction of Retinal Ganglion Cells in Dogs and Nonhuman Primates

Kizito-Tshitoko Tshilenge , Baptiste Ameline , Michel Weber , Alexandra Mendes-Madeira , Steven Nedellec et al.
Human gene therapy methods, 2016, 27 (3), pp.122 - 134. ⟨10.1089/hgtb.2016.034⟩
Journal articles inserm-01799021v1

Herpes Simplex Virus Type 1 ICP0 Protein Mediates Activation of Adeno-Associated Virus Type 2 rep Gene Expression from a Latent Integrated Form

Marie-Claude Geoffroy , Alberto Epstein , Estelle Toublanc , Philippe Moullier , Anna Salvetti et al.
Journal of Virology, 2004, 78 (20), pp.10977-10986. ⟨10.1128/JVI.78.20.10977-10986.2004⟩
Journal articles hal-03083404v1

Adeno-Associated Virus Vector (AAV) microdystrophin gene therapy prolongs survival and restores muscle function in the canine model of Duchenne Muscular Dystrophy (DMD)

Caroline Le Guiner , Laurent Servais , Marie Montus , Thibaut Larcher , Bodvael Fraysse et al.
19. Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy, May 2016, Washington, DC, United States. ⟨10.1016/S1525-0016(16)33312-3⟩
Conference papers hal-01602361v1

Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates.

Aurélie Moreau , Rita Vicente , Laurence Dubreil , Oumeya Adjali , Guillaume Podevin et al.
Molecular Therapy, 2009, 17 (3), pp.472-9. ⟨10.1038/mt.2008.272⟩
Journal articles hal-00420211v1

NGS library preparation may generate artifactual integration sites of AAV vectors

Benjamin Cogné , Richard Snyder , Pierre Lindenbaum , Jean-Baptiste Dupont , Richard Redon et al.
Nature Medicine, 2014, 20 (6), pp.577 - 578. ⟨10.1038/nm.3578⟩
Journal articles inserm-01800006v1
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RNA-Seq Analysis of an Antisense Sequence Optimized for Exon Skipping in Duchenne Patients Reveals No Off-Target Effect

Claire Domenger , Marine Allais , Virginie François , Adrien Leger , Emilie Lecomte et al.
Molecular Therapy - Nucleic Acids, 2018, 10, pp.277 - 291. ⟨10.1016/j.omtn.2017.12.008⟩
Journal articles inserm-01734756v1

Early Detection of a Two-Long-Terminal-Repeat Junction Molecule in the Cytoplasm of Recombinant Murine Leukemia Virus-Infected Cells

Fatima Serhan , Magalie Penaud , Caroline Petit , Thierry Leste-Lasserre , Stéphane Trajcevski et al.
Journal of Virology, 2004, 78 (12), pp.6190-6199. ⟨10.1128/JVI.78.12.6190-6199.2004⟩
Journal articles hal-03140785v1