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authFullName_s : Sandrine Ruchaud
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Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors

Bruno Oyallon , Marie Brachet-Botineau , Cédric Logé , Pascal Bonnet , Mohamed Souab et al.
European Journal of Medicinal Chemistry, 2018, 154, pp.101-109. ⟨10.1016/j.ejmech.2018.04.056⟩
Journal articles hal-03408667v1
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A Peak of H3T3 Phosphorylation Occurs in Synchrony with Mitosis in Sea Urchin Early Embryos

Omid Feizbakhsh , Florian Pontheaux , Virginie Glippa , Julia Morales , Sandrine Ruchaud et al.
Cells, 2020, Manufacturing a Female Gamete: An Oocyte Story, 9 (4), pp.898. ⟨10.3390/cells9040898⟩
Journal articles hal-02536773v1

The Canadian Prairie Plant Thermopsis rhombifolia Contains Luteolin, a Flavone that Inhibits Cyclin Dependent Kinase 9 and Arrest Cells in the G1-Phase of the Cell Cycle

Jan Tuescher , Deserae Tailfeathers , Sophie Kernéis , Blandine Baratte , Sandrine Ruchaud et al.
Journal of Natural Health Product Research, 2020, 2 (2), pp.1-14. ⟨10.33211/jnhpr.12⟩
Journal articles hal-03868334v1
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Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides

Sofia-Eléna Motuhi , Omid Feizbakhsh , Beatrice Foll-Josselin , Blandine Baratte , Claire Delehouze et al.
Marine drugs, 2019, Cell Stress, Canonical and Non-Canonical Cell Death Modalities by Marine Natural Compounds and Derivatives, 17 (2), pp.93. ⟨10.3390/md17020093⟩
Journal articles hal-02088007v1

Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration

Viet Hung Dao , Isabelle Ourliac-Garnier , Marc-Antoine Bazin , Catherine Jacquot , Blandine Baratte et al.
Bioorganic and Medicinal Chemistry, 2018, 28 (13), pp.2250-2255. ⟨10.1016/j.bmcl.2018.05.044⟩
Journal articles hal-03011408v1

Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition

Hannah Winfield , Michael Cahill , Kevin O'Shea , Larry Pierce , Thomas Robert et al.
Bioorganic and Medicinal Chemistry, 2018, 26 (14), pp.4209-4224. ⟨10.1016/j.bmc.2018.07.012⟩
Journal articles hal-03011414v1
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Synthesis and biological evaluation of Haspin inhibitors: kinase inhibitory potency and cellular activity

Wael Zeinyeh , Yannick Esvan , Béatrice Josselin , Mathilde Defois , Blandine Baratte et al.
European Journal of Medicinal Chemistry, 2022, 236, pp.114369. ⟨10.1016/j.ejmech.2022.114369⟩
Journal articles hal-03764791v1
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Bioprospecting Marine Plankton

Heni Abida , Sandrine Ruchaud , Laurent Rios , Anne Humeau , Ian Probert et al.
Marine drugs, 2013, 11 (11), pp.4594-4611. ⟨10.3390/md11114594⟩
Journal articles hal-01258229v1

Synthesis and kinase inhibitory potencies of new pyrido[3,4-g]quinazolines substituted at the 8-position

Yannick Esvan , Béatrice Josselin , Blandine Baratte , Stéphane Bach , Sandrine Ruchaud et al.
ARKIVOC - Online Journal of Organic Chemistry, 2020, 2020 (7), pp.105-116. ⟨10.24820/ark.5550190.p011.268⟩
Journal articles hal-02926291v1

Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors

Camille Déliko Dago , Wacothon Karime Coulibaly , Yves-Alain Bekro , Janat A. Mamyrbekova-Bekro , Beatrice Foll-Josselin et al.
Medicinal Chemistry Research, 2016, 25 (12), pp.2940--2958. ⟨10.1007/s00044-016-1719-3⟩
Journal articles hal-01414293v1
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High-Throughput Screening of marine resources

Arnaud Hochard , Luc Reininger , Sandrine Ruchaud , Stéphane Bach
Outstanding Marine Molecules, 2015, ⟨10.1002/9783527681501.ch23⟩
Book sections hal-03871307v1

Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

Madani Hedidi , Julien Maillard , William Erb , Frédéric Lassagne , Yury Halauko et al.
Tetrahedron, 2016, 72 (39), pp.6467 - 6476. ⟨10.1016/j.tet.2016.08.056⟩
Journal articles hal-03875302v1
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New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis

Helmi Tazarki , Wael Zeinyeh , Yannick J. Esvan , Stefan Knapp , Deep Chatterjee et al.
European Journal of Medicinal Chemistry, 2019, 166, pp.304-317. ⟨10.1016/j.ejmech.2019.01.052⟩
Journal articles hal-02150788v1

Synthesis and evaluation of C3 substituted chalcone‐based derivatives of 7‐azaindole as protein kinase inhibitors

Malikotsi Qhobosheane , Lesetja Legoabe , Béatrice Josselin , Stéphane Bach , Sandrine Ruchaud et al.
Chemical Biology and Drug Design, In press, ⟨10.1111/cbdd.13748⟩
Journal articles hal-02906292v1
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30th Franco-Belgian conference of pharmacochemistry

Charlotte Bouckaert , Eric Goffin , Sebastien Dilly , Julien Hanson , Lionel Pochet et al.
Pharmaceuticals, 2016, 9 (4), pp.73. ⟨10.3390/ph9040073⟩
Journal articles hal-02141338v1
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Synthesis, biological evaluation and molecular modeling studies of imidazo[1,2- a ]pyridines derivatives as protein kinase inhibitors

Marie Lawson , Jordi Rodrigo , Blandine Baratte , Thomas Robert , Claire Delehouzé et al.
European Journal of Medicinal Chemistry, 2016, 123, pp.105 - 114. ⟨10.1016/j.ejmech.2016.07.040⟩
Journal articles hal-03875851v1

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Cédric Logé , Mélanie Pénichon et al.
European Journal of Medicinal Chemistry, 2015, 105, pp.80-105. ⟨10.1016/j.ejmech.2015.10.004⟩
Journal articles hal-02389861v1
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Design and biological evaluation of substituted 5,7-dihydro-6 H -indolo[2,3- c ]quinolin-6-one as novel selective Haspin inhibitors

Sreenivas Avula , Xudan Peng , Xingfen Lang , Micky Tortorella , Béatrice Josselin et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022, 37 (1), pp.1632-1650. ⟨10.1080/14756366.2022.2082419⟩
Journal articles hal-03818922v1
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From simple quinoxalines to potent oxazolo[5,4- f ]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3)

Frédéric Lassagne , Camille Duguépéroux , Carlos Roca , Concepcion Perez , Ana Martinez et al.
Organic & Biomolecular Chemistry, 2020, 18 (1), pp.154-162. ⟨10.1039/c9ob02002k⟩
Journal articles hal-03011380v1
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The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases

Maciej Masłyk , Monika Janeczko , Aleksandra Martyna , Sławomir Czernik , Małgorzata Tokarska-Rodak et al.
Molecules, 2019, 24 (1), pp.153. ⟨10.3390/molecules24010153⟩
Journal articles hal-02046526v1

Synthesis and Kinase Inhibitory Potencies of Pyrazolo[3,4-g]Isoquinolines

Mathilde Defois , Chloé Rémondin , Béatrice Josselin , Lionel Nauton , Vincent Théry et al.
Molecules, 2022, 27 (17), pp.5578. ⟨10.3390/molecules27175578⟩
Journal articles hal-03765284v1

Synthesis and biological evaluation of selected 7H-pyrrolo[2,3-d]pyrimidine derivatives as novel CDK9/CyclinT and Haspin inhibitors

Lianie Pieterse , Richard Beteck , Blandine Baratte , Omobolanle Jesumoroti , Thomas Robert et al.
Chemico-Biological Interactions, 2021, 349, pp.109643. ⟨10.1016/j.cbi.2021.109643⟩
Journal articles hal-03864115v1
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Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1

Mohamed Benchekroun , Ludmila Ermolenko , Minh Quan Tran , Agathe Vagneux , Hristo Nedev et al.
European Journal of Medicinal Chemistry, 2020, 201, pp.112337. ⟨10.1016/j.ejmech.2020.112337⟩
Journal articles hal-03004425v2
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Reactivity Under Microwave Irradiation of 2-amino 4H-chromene-3-carbonitrile as tool for the construction of potential bioactive derivatives

Ali Bouattour , Mehdi Fakhfakh , Houcine Ammar , Ludovic Paquin , Jean-Pierre Bazureau et al.
3rd International Electronic Conference on Medicinal Chemistry, Nov 2022, Online, France
Conference papers hal-03872422v1
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Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

Camille Déliko Dago , Christelle Ambeu , Wacothon-Karime Coulibaly , Yves-Alain Békro , Janat Mamyrbékova et al.
Molecules, 2015, 20 (7), pp.12412-12435. ⟨10.3390/molecules200712412⟩
Journal articles hal-01187427v1
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From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines

Frédéric Lassagne , Timothy Langlais , Elsa Caytan , Emmanuelle Limanton , Ludovic Paquin et al.
Molecules, 2018, 23 (11), pp.2961. ⟨10.3390/molecules23112961⟩
Journal articles hal-03867783v1

Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors

Malikotsi Qhobosheane , Richard Beteck , Blandine Baratte , Thomas Robert , Sandrine Ruchaud et al.
Chemico-Biological Interactions, 2021, 343, pp.109478. ⟨10.1016/j.cbi.2021.109478⟩
Journal articles hal-03864214v1
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From drug screening to target deconvolution: A target-based drug discovery pipeline using Leishmania casein kinase 1 isoform 2 to identify compounds with anti-leishmanial activity

Emilie Durieu , Eric Prina , Olivier Leclercq , Nassima Oumata , Nicolas Gaboriaud-Kolar et al.
Antimicrobial Agents and Chemotherapy, 2016, ⟨10.1128/AAC.00021-16⟩
Journal articles hal-01299756v1

Développement de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Cedric Logé , Mélanie Pénichon et al.
6. Journées du Consortium antiParasitaire et antiFongique : CaPF-2016 " A la croisée des Mondes !", Consortium Anti-Parasitaire et Fongique (CaPF). FRA., Mar 2016, Tours, France. 49 p
Conference papers hal-02739722v1

Conception, synthèse et évaluation de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Mélanie Pouvreau , Nathalie Moiré et al.
28. Colloque Biotechnocentre, Biotechnocentre. FRA., Oct 2015, Seillac, France
Conference papers hal-02744066v1