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The CDK4-pRB-E2F1 pathway controls insulin secretion.
Jean-Sébastien Annicotte
,
Emilie Blanchet
,
Carine Chavey
,
Irena Iankova
,
Safia Costes
et al.
Journal articles
inserm-00418907v1
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GLP-1-based strategies: a physiological analysis of differential mode of action.
Rémy Burcelin
,
Pierre Gourdy
,
Stéphane Dalle
Journal articles
inserm-00995704v1
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Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B
Guillaume Fontes
,
A.D. Lajoix
,
F. Bergeron
,
S. Cadel
,
A. Prat
et al.
Journal articles
hal-00017011v1
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Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma
Nicolas Jacquelot
,
David P. Enot
,
Caroline Flament
,
Nadège Vimond
,
Carolin Blattner
et al.
Journal articles
hal-01295136v1
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Rôles différentiels de la β-arrestine 2 dans la signalisation des récepteurs du GLP-1 et du GIP dans les cellules β pancréatiques
Gyslaine Bertrand
,
Joelle Obeid
,
Michèle Leduc
,
Safia Costes
,
Stéphane Dalle
et al.
SFD 2019, 2019, Marseille, France
Conference papers
hal-03020319v1
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ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival.
Safia Costes
,
Christophe Broca
,
Gyslaine Bertrand
,
Anne-Dominique Lajoix
,
Dominique Bataille
et al.
Journal articles
hal-00201283v1
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La β-arrestine 2 est indispensable pour l'effet insulino-sécréteur du GIP
Gyslaine Bertrand
,
Joelle Obeid
,
Michèle Leduc
,
Safia Costes
,
Stéphane Dalle
et al.
Société Francophone du Diabète 2020, 2020, Bruxelles, Belgique
Conference papers
hal-03020293v1
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Opposite functions of beta-arrestin2 for the potentiation of insulin secretion by GLP-1 and GIP
Magalie A Ravier
,
Joelle Obeid
,
Safia Costes
,
Michèle Leduc
,
Christophe Broca
et al.
EASD Barcelona, Sep 2019, Barcelona, Spain
Conference papers
hal-03020271v1
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microRNA-375 regulates glucose metabolism-related signaling for insulin secretion
Olivier Dumortier
,
Gaia Fabris
,
Didier Pisani
,
Virginie Casamento
,
Nadine Gautier
et al.
Journal articles
hal-02400345v1
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Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial
Alexander Eggermont
,
Christian U. Blank
,
Mario Mandalà
,
Georgina Long
,
Victoria A Atkinson
et al.
Journal articles
hal-03670721v1
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The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions
Matthew Brown
,
Damien Laouteouet
,
Morgane Delobel
,
Orianne Villard
,
Christophe Broca
et al.
Journal articles
hal-03647414v1
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The circadian clock nuclear receptor Rev-erbα is implicated in autophagy alteration and beta cell deficit under diabetogenic conditions.
Safia Costes
,
Damien Laouteouet
,
Magalie A Ravier
,
Morgane Delobel
,
Gyslaine Bertrand
et al.
EASD Virtual meeting, 2020, Vienne, Austria
Conference papers
hal-03020248v1
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Association of Time From Primary Diagnosis to First Distant Relapse of Metastatic Melanoma With Progression of Disease and Survival
Anaïs Vallet
,
Bastien Oriano
,
Laurent Mortier
,
Stéphane Dalle
,
Caroline Dutriaux
et al.
Journal articles
hal-02863397v1
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The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development
Mathie Tenenbaum
,
Valérie Plaisance
,
Raphael Boutry
,
Valérie Pawlowski
,
Cécile Jacovetti
et al.
Journal articles
hal-03142227v1
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Molecular mechanisms redirecting the GLP-1 receptor signalling profile in pancreatic β-cells during type 2 diabetes
Morgane Roussel
,
Julia Mathieu
,
Stéphane Dalle
Journal articles
hal-01800004v1
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Diabetes: What are the key targets and the objectives? Preserving and protecting a functional pancreatic beta cell mass
Stéphane Dalle
Journal articles
hal-02063686v1
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An in vivo avian model of human melanoma to perform rapid and robust preclinical studies
Loraine Jarrosson
,
Stéphane Dalle
,
Clélia Costechareyre
,
Yaqi Tang
,
Maxime Grimont
et al.
2022
Preprints, Working Papers, ...
hal-03854621v1
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G-protein–coupled receptors controlling pancreatic β-cell functional mass for the treatment of type 2 diabetes
Morgane Delobel
,
Stéphane Dalle
Journal articles
hal-03493171v1
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Left ventricular ejection fraction decrease related to BRAF and/or MEK inhibitors in metastatic melanoma patients: A retrospective analysis
Mathilde Berger
,
Mona Amini‐adlé
,
Delphine Maucort‐boulch
,
Philip Robinson
,
Luc Thomas
et al.
Journal articles
hal-03149088v1
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Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B.
Ghislaine Fontés
,
Anne-Dominique Lajoix
,
François Bergeron
,
Sandrine Cadel
,
Annik Prat
et al.
Journal articles
hal-00358734v1
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CD1d-restricted peripheral T cell lymphoma in mice and humans
Emmanuel Bachy
,
Mirjam Urb
,
Shilpi Chandra
,
Rémy Robinot
,
Gabriel Bricard
et al.
Journal articles
hal-01305487v1
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Circadian clock nuclear receptor REV-ERBα is a novel regulator of beta-cell function, survival and autophagy under diabetogenic conditions
Safia Costes
,
Damien Laouteouet
,
Magalie A Ravier
,
Morgane Delobel
,
Gyslaine Bertrand
et al.
EASD Barcelona, Sep 2019, Barcelone, Spain
Conference papers
hal-03020279v1
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HAVCR2 mutations are associated with severe hemophagocytic syndrome in subcutaneous panniculitis-like T-cell lymphoma
Gabrielle Sonigo
,
Maxime Battistella
,
Marie Beylot-Barry
,
Saskia Ingen-Housz-Oro
,
Nathalie Franck
et al.
Journal articles
hal-02882288v1
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Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
C. Bertolotto
,
F. Lesueur
,
S. Giuliano
,
T. Strub
,
Lichy M. De
et al.
Journal articles
hal-01791271v1
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ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB
Michèle Leduc
,
Joy Richard
,
Safia Costes
,
Dany Muller
,
Annie Varrault
et al.
Journal articles
hal-02073008v1
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The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death
Jonathan Vial
,
Amélie Royet
,
Philippe Cassier
,
Antonin Tortereau
,
Sarah Dinvaut
et al.
Journal articles
hal-01960268v1
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EMT-Inducing Transcription Factors, Drivers of Melanoma Phenotype Switching, and Resistance to Treatment
Yaqi Tang
,
Simon Durand
,
Stéphane Dalle
,
Julie Caramel
Journal articles
hal-03768989v1
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Real-world effectiveness of pembrolizumab in advanced melanoma: analysis of a French national clinicobiological database
Emilie Casarotto
,
Sheenu Chandwani
,
Laurent Mortier
,
Olivier Dereure
,
Caroline Dutriaux
et al.
Journal articles
hal-03713274v1
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Les effets d’un agoniste du récepteur GLP-1 sur les cellules bêta pancréatiques sont renforcés par combinaison avec un inhibiteur de la kinase TPL2
Morgane Delobel
,
Valérie Plaisance
,
Gyslaine Bertrand
,
Safia Costes
,
Christophe Broca
et al.
Société Francophone du Diabète, Strasbourg 2021, 2021, Strasbourg, France
Conference papers
hal-03811301v1
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Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study
Georgina Long
,
Reinhard Dummer
,
Omid Hamid
,
Thomas Gajewski
,
Christian Caglevic
et al.
Journal articles
hal-04030780v1
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