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authFullName_s : Stéphane Dalle
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The CDK4-pRB-E2F1 pathway controls insulin secretion.

Jean-Sébastien Annicotte , Emilie Blanchet , Carine Chavey , Irena Iankova , Safia Costes et al.
Nature Cell Biology, 2009, 11 (8), pp.1017-23. ⟨10.1038/ncb1915⟩
Journal articles inserm-00418907v1

GLP-1-based strategies: a physiological analysis of differential mode of action.

Rémy Burcelin , Pierre Gourdy , Stéphane Dalle
News in Physiological Sciences, 2014, 29 (2), pp.108-21. ⟨10.1152/physiol.00009.2013⟩
Journal articles inserm-00995704v1

Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B

Guillaume Fontes , A.D. Lajoix , F. Bergeron , S. Cadel , A. Prat et al.
Endocrinology, 2005, 142, pp.702-712. ⟨10.1210/en.2004-0853⟩
Journal articles hal-00017011v1
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Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma

Nicolas Jacquelot , David P. Enot , Caroline Flament , Nadège Vimond , Carolin Blattner et al.
Journal of Clinical Investigation, 2016, 126 (3), pp.921-937. ⟨10.1172/JCI80071⟩
Journal articles hal-01295136v1

Rôles différentiels de la β-arrestine 2 dans la signalisation des récepteurs du GLP-1 et du GIP dans les cellules β pancréatiques

Gyslaine Bertrand , Joelle Obeid , Michèle Leduc , Safia Costes , Stéphane Dalle et al.
SFD 2019, 2019, Marseille, France
Conference papers hal-03020319v1

ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival.

Safia Costes , Christophe Broca , Gyslaine Bertrand , Anne-Dominique Lajoix , Dominique Bataille et al.
Diabetes, 2006, 55 (8), pp.2220-30. ⟨10.2337/db05-1618⟩
Journal articles hal-00201283v1

La β-arrestine 2 est indispensable pour l'effet insulino-sécréteur du GIP

Gyslaine Bertrand , Joelle Obeid , Michèle Leduc , Safia Costes , Stéphane Dalle et al.
Société Francophone du Diabète 2020, 2020, Bruxelles, Belgique
Conference papers hal-03020293v1

Opposite functions of beta-arrestin2 for the potentiation of insulin secretion by GLP-1 and GIP

Magalie A Ravier , Joelle Obeid , Safia Costes , Michèle Leduc , Christophe Broca et al.
EASD Barcelona, Sep 2019, Barcelona, Spain
Conference papers hal-03020271v1
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microRNA-375 regulates glucose metabolism-related signaling for insulin secretion

Olivier Dumortier , Gaia Fabris , Didier Pisani , Virginie Casamento , Nadine Gautier et al.
Journal of Endocrinology, 2020, 244 (1), pp.189-200. ⟨10.1530/JOE-19-0180⟩
Journal articles hal-02400345v1

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial

Alexander Eggermont , Christian U. Blank , Mario Mandalà , Georgina Long , Victoria A Atkinson et al.
Lancet Oncology, 2021, 22 (5), pp.643-654. ⟨10.1016/S1470-2045(21)00065-6⟩
Journal articles hal-03670721v1
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The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions

Matthew Brown , Damien Laouteouet , Morgane Delobel , Orianne Villard , Christophe Broca et al.
Cell Death and Disease, 2022, 13 (4), pp.353. ⟨10.1038/s41419-022-04767-z⟩
Journal articles hal-03647414v1

The circadian clock nuclear receptor Rev-erbα is implicated in autophagy alteration and beta cell deficit under diabetogenic conditions.

Safia Costes , Damien Laouteouet , Magalie A Ravier , Morgane Delobel , Gyslaine Bertrand et al.
EASD Virtual meeting, 2020, Vienne, Austria
Conference papers hal-03020248v1

Association of Time From Primary Diagnosis to First Distant Relapse of Metastatic Melanoma With Progression of Disease and Survival

Anaïs Vallet , Bastien Oriano , Laurent Mortier , Stéphane Dalle , Caroline Dutriaux et al.
JAMA Dermatology, 2019, 155 (6), pp.673. ⟨10.1001/jamadermatol.2019.0425⟩
Journal articles hal-02863397v1
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The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development

Mathie Tenenbaum , Valérie Plaisance , Raphael Boutry , Valérie Pawlowski , Cécile Jacovetti et al.
Cellular and Molecular Life Sciences, 2021, 78 (1), pp.287-298. ⟨10.1007/s00018-020-03499-7⟩
Journal articles hal-03142227v1

Molecular mechanisms redirecting the GLP-1 receptor signalling profile in pancreatic β-cells during type 2 diabetes

Morgane Roussel , Julia Mathieu , Stéphane Dalle
Hormone Molecular Biology and Clinical Investigation, 2016, 26 (2), ⟨10.1515/hmbci-2015-0071⟩
Journal articles hal-01800004v1

Diabetes: What are the key targets and the objectives? Preserving and protecting a functional pancreatic beta cell mass

Stéphane Dalle
Biologie Aujourd'hui, 2017, 211 (2), pp.165-168. ⟨10.1051/jbio/2017018⟩
Journal articles hal-02063686v1

An in vivo avian model of human melanoma to perform rapid and robust preclinical studies

Loraine Jarrosson , Stéphane Dalle , Clélia Costechareyre , Yaqi Tang , Maxime Grimont et al.
2022
Preprints, Working Papers, ... hal-03854621v1
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G-protein–coupled receptors controlling pancreatic β-cell functional mass for the treatment of type 2 diabetes

Morgane Delobel , Stéphane Dalle
Current Opinion in Endocrine and Metabolic Research, 2021, 16, pp.113 - 118. ⟨10.1016/j.coemr.2020.09.010⟩
Journal articles hal-03493171v1

Left ventricular ejection fraction decrease related to BRAF and/or MEK inhibitors in metastatic melanoma patients: A retrospective analysis

Mathilde Berger , Mona Amini‐adlé , Delphine Maucort‐boulch , Philip Robinson , Luc Thomas et al.
Cancer Medicine, 2020, 9 (8), pp.2611-2620. ⟨10.1002/cam4.2922⟩
Journal articles hal-03149088v1

Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B.

Ghislaine Fontés , Anne-Dominique Lajoix , François Bergeron , Sandrine Cadel , Annik Prat et al.
Endocrinology, 2005, 146 (2), pp.702-12. ⟨10.1210/en.2004-0853⟩
Journal articles hal-00358734v1

CD1d-restricted peripheral T cell lymphoma in mice and humans

Emmanuel Bachy , Mirjam Urb , Shilpi Chandra , Rémy Robinot , Gabriel Bricard et al.
Journal of Experimental Medicine, 2016, 213 (5), pp.841-57. ⟨10.1084/jem.20150794⟩
Journal articles hal-01305487v1

Circadian clock nuclear receptor REV-ERBα is a novel regulator of beta-cell function, survival and autophagy under diabetogenic conditions

Safia Costes , Damien Laouteouet , Magalie A Ravier , Morgane Delobel , Gyslaine Bertrand et al.
EASD Barcelona, Sep 2019, Barcelone, Spain
Conference papers hal-03020279v1
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HAVCR2 mutations are associated with severe hemophagocytic syndrome in subcutaneous panniculitis-like T-cell lymphoma

Gabrielle Sonigo , Maxime Battistella , Marie Beylot-Barry , Saskia Ingen-Housz-Oro , Nathalie Franck et al.
Blood, 2020, 135 (13), pp.1058-1061. ⟨10.1182/blood.2019003811⟩
Journal articles hal-02882288v1

Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

C. Bertolotto , F. Lesueur , S. Giuliano , T. Strub , Lichy M. De et al.
Nature, 2016, 531, pp.126. ⟨10.1038/nature16158⟩
Journal articles hal-01791271v1

ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB

Michèle Leduc , Joy Richard , Safia Costes , Dany Muller , Annie Varrault et al.
Diabetologia, 2017, 60 (10), pp.1999-2010. ⟨10.1007/s00125-017-4356-6⟩
Journal articles hal-02073008v1

The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death

Jonathan Vial , Amélie Royet , Philippe Cassier , Antonin Tortereau , Sarah Dinvaut et al.
Cell Death and Differentiation, 2019, 26, pp.443-454. ⟨10.1038/s41418-018-0128-1⟩
Journal articles hal-01960268v1

EMT-Inducing Transcription Factors, Drivers of Melanoma Phenotype Switching, and Resistance to Treatment

Yaqi Tang , Simon Durand , Stéphane Dalle , Julie Caramel
Cancers, 2020, 12 (8), pp.2154. ⟨10.3390/cancers12082154⟩
Journal articles hal-03768989v1
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Real-world effectiveness of pembrolizumab in advanced melanoma: analysis of a French national clinicobiological database

Emilie Casarotto , Sheenu Chandwani , Laurent Mortier , Olivier Dereure , Caroline Dutriaux et al.
Immunotherapy, 2021, 13 (11), pp.905-916. ⟨10.2217/imt-2021-0077⟩
Journal articles hal-03713274v1

Les effets d’un agoniste du récepteur GLP-1 sur les cellules bêta pancréatiques sont renforcés par combinaison avec un inhibiteur de la kinase TPL2

Morgane Delobel , Valérie Plaisance , Gyslaine Bertrand , Safia Costes , Christophe Broca et al.
Société Francophone du Diabète, Strasbourg 2021, 2021, Strasbourg, France
Conference papers hal-03811301v1

Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study

Georgina Long , Reinhard Dummer , Omid Hamid , Thomas Gajewski , Christian Caglevic et al.
Lancet Oncology, 2019, 20 (8), pp.1083-1097. ⟨10.1016/S1470-2045(19)30274-8⟩
Journal articles hal-04030780v1