Why Is Evolution Important in Cancer and What Mathematics Should Be Used to Treat Cancer? Focus on Drug Resistance
Luís Almeida
,
Rebecca H Chisholm
,
Jean Clairambault
,
Tommaso Lorenzi
,
Alexander Lorz
et al.
Trends in Biomathematics: Modeling, Optimization and Computational Problems: Selected works from the BIOMAT Consortium Lectures, Moscow 2017 , Springer International Publishing, pp.107-120, 2018
Book sections
hal-01618357v2
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Tumour growth and drug resistance: an evolutionary view with perspectives in therapeutics
Jean Clairambault
,
Luís Almeida
,
Rebecca Chisholm
,
Tommaso Lorenzi
,
Alexander Lorz
et al.
ECMTB 2016 - European Conference on Mathematical and Theoretical Biology , Jul 2016, Nottingham, United Kingdom. 2016
Conference poster
hal-01378290v1
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Emergence of cytotoxic resistance in cancer cell populations
Tommaso Lorenzi
,
Rebecca H. Chisholm
,
Alexander Lorz
,
Annette K Larsen
,
Luís Almeida
et al.
Workshop on Multiscale and Hybrid Modelling in Cell and Cell Population Biology , V. Volpert and J. Clairambault, Mar 2015, Paris, France.
⟨10.1051/itmconf/20150500009⟩
Conference papers
hal-01249235v1
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Mathematical model reveals how regulating the three phases of T-cell response could counteract immune evasion
Tommaso Lorenzi
,
Rebecca H. Chisholm
,
Matteo Melensi
,
Alexander Lorz
,
Marcello Delitala
et al.
Journal articles
hal-01237852v1
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A hybrid discrete-continuum modelling approach to explore the impact of T-cell infiltration on anti-tumour immune response
Luis Almeida
,
Chloe Audebert
,
Emma Leschiera
,
Tommaso Lorenzi
Bulletin of Mathematical Biology , In press
Journal articles
hal-03722100v3
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Evolutionary dynamics of glucose-deprived cancer cells: insights from experimentally-informed mathematical modelling
Jérôme Denis
,
Nathalie Ferrand
,
Tommaso Lorenzi
,
Michéle Sabbah
,
Chiara Villa
et al.
2023
Preprints, Working Papers, ...
hal-03947209v1
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Effects of an advection term in nonlocal Lotka-Volterra equations
Tommaso Lorenzi
,
Rebecca H. Chisholm
,
Alexander Lorz
2015
Preprints, Working Papers, ...
hal-01237529v1
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Discrete and continuum models for the coevolutionary dynamics between CD8+ cytotoxic T lymphocytes and tumour cells
Luís Almeida
,
Chloe Audebert
,
Emma Leschiera
,
Tommaso Lorenzi
Journal articles
hal-03348931v2
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Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model
Luís Almeida
,
Patrizia Bagnerini
,
Giulia Fabrini
,
Barry D Hughes
,
Tommaso Lorenzi
et al.
Journal articles
hal-02433962v1
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On interfaces between cell populations with different mobilities
Tommaso Lorenzi
,
Alexander Lorz
,
Benoît Perthame
Kinetic and Related Models , 2017, 10 (1), pp.299-311
Journal articles
hal-01257180v2
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Asymptotic analysis of selection-mutation models in the presence of multiple fitness peaks
Tommaso Lorenzi
,
Camille Pouchol
Journal articles
hal-02076479v5
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Modelling targets for anticancer drug control optimisation in physiologically structured cell population models
Frédérique Billy
,
Jean Clairambault
,
Olivier Fercoq
,
Tommaso Lorenzi
,
Alexander Lorz
et al.
ICNAAM 2012 - 10th international conference of numerical analysis and applied mathematics , Simos, Thodoros, Sep 2012, Kos, Greece. pp.1323-1326,
⟨10.1063/1.4756399⟩
Conference papers
hal-00780721v1
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Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors
Alexander Lorz
,
Tommaso Lorenzi
,
Jean Clairambault
,
Alexandre Escargueil
,
Benoît Perthame
et al.
Journal articles
hal-00921266v2
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Phenotype heterogeneity in cancer cell populations
Luis Almeida
,
Rebecca H. Chisholm
,
Jean Clairambault
,
Alexandre Escargueil
,
Tommaso Lorenzi
et al.
ICNAAM 2015 Session 70: "Mathematical models and methods to investigate heterogeneity in cell and cell population biology'' , Jean Clairambault, Sep 2015, Rhodes, Greece
Conference papers
hal-01249242v1
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A mathematical model to study the impact of intra-tumour heterogeneity on anti-tumour CD8 + T cell immune response
Emma Leschiera
,
Tommaso Lorenzi
,
Shensi Shen
,
Luis Almeida
,
Chloe Audebert
et al.
Journal of Theoretical Biology , 2022
Journal articles
hal-03283699v2
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Invasion fronts and adaptive dynamics in a model for the growth of cell populations with heterogeneous mobility
Tommaso Lorenzi
,
Benoît Perthame
,
Xinran Ruan
Journal articles
hal-03611324v1
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Emergence of cytotoxic resistance in cancer cell populations: single-cell mechanisms and population-level consequences
Tommaso Lorenzi
,
Rebecca H. Chisholm
,
Alexander Lorz
,
Annette K Larsen
,
Luís Almeida
et al.
ICNAAM 2015 Session 70: "Mathematical models and methods to investigate heterogeneity in cell and cell population biology" , Jean Clairambault, Sep 2015, Rhodes, Greece
Conference papers
hal-01249239v1
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Dissecting the dynamics of epigenetic changes in phenotype-structured populations exposed to fluctuating environments
Tommaso Lorenzi
,
Rebecca H. Chisholm
,
Laurent Desvillettes
,
Barry D. Hughes
Journal articles
hal-01237890v1
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Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
Rebecca H. Chisholm
,
Tommaso Lorenzi
,
Alexander Lorz
,
Annette K. Larsen
,
Luís Almeida
et al.
Journal articles
hal-01237893v1
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Tracking the evolution of cancer cell populations through the mathematical lens of phenotype-structured equations
Tommaso Lorenzi
,
Rebecca H. Chisholm
,
Jean Clairambault
Journal articles
hal-01355314v1
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Social information use and the evolution of unresponsiveness in collective systems
Colin J Torney
,
Tommaso Lorenzi
,
Iain D Couzin
,
Simon A Levin
Journal articles
hal-01237894v1
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Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, non-genetic instability and stress-induced adaptation
Rebecca H. Chisholm
,
Tommaso Lorenzi
,
Alexander Lorz
,
Annette K. Larsen
,
Luís Almeida
et al.
2015
Preprints, Working Papers, ...
hal-01111271v1
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Preface to Session 70 " Mathematical models and methods to investigate heterogeneity in cell and cell population biology
Loic Barbarroux
,
Jean Clairambault
,
Nick Cogan
,
Jan Elias
,
Shalla Hanson
et al.
ICNAAM 2015 Session 70: "Mathematical models and methods to investigate heterogeneity in cell and cell population biology'' , Organiser Session 70: Jean Clairambault, Sep 2015, Rhodes, Greece
Conference papers
hal-01249244v1
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Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies
Alexander Lorz
,
Tommaso Lorenzi
,
Michael E. Hochberg
,
Jean Clairambault
,
Benoît Perthame
et al.
Journal articles
hal-00714274v1
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A mathematical model to study the impact of intra-tumour heterogeneity on anti-tumour CD8+ T cell immune response
Emma Leschiera
,
Tommaso Lorenzi
,
Shensi Shen
,
Luis Almeida
,
Chloe Audebert
et al.
Journal articles
hal-03673890v1
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