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authFullName_s : Tommaso Lorenzi
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Why Is Evolution Important in Cancer and What Mathematics Should Be Used to Treat Cancer? Focus on Drug Resistance

Luís Almeida , Rebecca H Chisholm , Jean Clairambault , Tommaso Lorenzi , Alexander Lorz et al.
Trends in Biomathematics: Modeling, Optimization and Computational Problems: Selected works from the BIOMAT Consortium Lectures, Moscow 2017, Springer International Publishing, pp.107-120, 2018
Book sections hal-01618357v2
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Tumour growth and drug resistance: an evolutionary view with perspectives in therapeutics

Jean Clairambault , Luís Almeida , Rebecca Chisholm , Tommaso Lorenzi , Alexander Lorz et al.
ECMTB 2016 - European Conference on Mathematical and Theoretical Biology, Jul 2016, Nottingham, United Kingdom. 2016
Conference poster hal-01378290v1
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Emergence of cytotoxic resistance in cancer cell populations

Tommaso Lorenzi , Rebecca H. Chisholm , Alexander Lorz , Annette K Larsen , Luís Almeida et al.
Workshop on Multiscale and Hybrid Modelling in Cell and Cell Population Biology, V. Volpert and J. Clairambault, Mar 2015, Paris, France. ⟨10.1051/itmconf/20150500009⟩
Conference papers hal-01249235v1

Mathematical model reveals how regulating the three phases of T-cell response could counteract immune evasion

Tommaso Lorenzi , Rebecca H. Chisholm , Matteo Melensi , Alexander Lorz , Marcello Delitala et al.
Immunology, 2015, 146 (2), pp.271-280. ⟨10.1111/imm.12500⟩
Journal articles hal-01237852v1
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A hybrid discrete-continuum modelling approach to explore the impact of T-cell infiltration on anti-tumour immune response

Luis Almeida , Chloe Audebert , Emma Leschiera , Tommaso Lorenzi
Bulletin of Mathematical Biology, In press
Journal articles hal-03722100v3
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Evolutionary dynamics of glucose-deprived cancer cells: insights from experimentally-informed mathematical modelling

Jérôme Denis , Nathalie Ferrand , Tommaso Lorenzi , Michéle Sabbah , Chiara Villa et al.
2023
Preprints, Working Papers, ... hal-03947209v1

Effects of an advection term in nonlocal Lotka-Volterra equations

Tommaso Lorenzi , Rebecca H. Chisholm , Alexander Lorz
2015
Preprints, Working Papers, ... hal-01237529v1
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Discrete and continuum models for the coevolutionary dynamics between CD8+ cytotoxic T lymphocytes and tumour cells

Luís Almeida , Chloe Audebert , Emma Leschiera , Tommaso Lorenzi
Mathematical Medicine and Biology, 2023, ⟨10.1093/imammb/dqac017⟩
Journal articles hal-03348931v2
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Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model

Luís Almeida , Patrizia Bagnerini , Giulia Fabrini , Barry D Hughes , Tommaso Lorenzi et al.
ESAIM: Mathematical Modelling and Numerical Analysis, 2019, 53 (4), pp.1157-1190. ⟨10.1051/m2an/2019010⟩
Journal articles hal-02433962v1
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On interfaces between cell populations with different mobilities

Tommaso Lorenzi , Alexander Lorz , Benoît Perthame
Kinetic and Related Models , 2017, 10 (1), pp.299-311
Journal articles hal-01257180v2
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Asymptotic analysis of selection-mutation models in the presence of multiple fitness peaks

Tommaso Lorenzi , Camille Pouchol
Nonlinearity, 2020, ⟨10.1088/1361-6544/ab9bad⟩
Journal articles hal-02076479v5
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Modelling targets for anticancer drug control optimisation in physiologically structured cell population models

Frédérique Billy , Jean Clairambault , Olivier Fercoq , Tommaso Lorenzi , Alexander Lorz et al.
ICNAAM 2012 - 10th international conference of numerical analysis and applied mathematics, Simos, Thodoros, Sep 2012, Kos, Greece. pp.1323-1326, ⟨10.1063/1.4756399⟩
Conference papers hal-00780721v1
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Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors

Alexander Lorz , Tommaso Lorenzi , Jean Clairambault , Alexandre Escargueil , Benoît Perthame et al.
Bulletin of Mathematical Biology, 2015, 77 (1), pp.1-22. ⟨10.1007/s11538-014-0046-4⟩
Journal articles hal-00921266v2
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Phenotype heterogeneity in cancer cell populations

Luis Almeida , Rebecca H. Chisholm , Jean Clairambault , Alexandre Escargueil , Tommaso Lorenzi et al.
ICNAAM 2015 Session 70: "Mathematical models and methods to investigate heterogeneity in cell and cell population biology'', Jean Clairambault, Sep 2015, Rhodes, Greece
Conference papers hal-01249242v1
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A mathematical model to study the impact of intra-tumour heterogeneity on anti-tumour CD8 + T cell immune response

Emma Leschiera , Tommaso Lorenzi , Shensi Shen , Luis Almeida , Chloe Audebert et al.
Journal of Theoretical Biology, 2022
Journal articles hal-03283699v2
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Invasion fronts and adaptive dynamics in a model for the growth of cell populations with heterogeneous mobility

Tommaso Lorenzi , Benoît Perthame , Xinran Ruan
European Journal of Applied Mathematics, 2022, pp.1-18. ⟨10.1017/S0956792521000218⟩
Journal articles hal-03611324v1
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Emergence of cytotoxic resistance in cancer cell populations: single-cell mechanisms and population-level consequences

Tommaso Lorenzi , Rebecca H. Chisholm , Alexander Lorz , Annette K Larsen , Luís Almeida et al.
ICNAAM 2015 Session 70: "Mathematical models and methods to investigate heterogeneity in cell and cell population biology", Jean Clairambault, Sep 2015, Rhodes, Greece
Conference papers hal-01249239v1
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Dissecting the dynamics of epigenetic changes in phenotype-structured populations exposed to fluctuating environments

Tommaso Lorenzi , Rebecca H. Chisholm , Laurent Desvillettes , Barry D. Hughes
Journal of Theoretical Biology, 2015, 386, pp.166-176. ⟨10.1016/j.jtbi.2015.08.031⟩
Journal articles hal-01237890v1

Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation

Rebecca H. Chisholm , Tommaso Lorenzi , Alexander Lorz , Annette K. Larsen , Luís Almeida et al.
Cancer Research, 2015, 75 (6), pp.930-939. ⟨10.1158/0008-5472.CAN-14-2103⟩
Journal articles hal-01237893v1
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Tracking the evolution of cancer cell populations through the mathematical lens of phenotype-structured equations

Tommaso Lorenzi , Rebecca H. Chisholm , Jean Clairambault
Biology Direct, 2016, 11 (1), pp.43. ⟨10.1186/s13062-016-0143-4⟩
Journal articles hal-01355314v1

Social information use and the evolution of unresponsiveness in collective systems

Colin J Torney , Tommaso Lorenzi , Iain D Couzin , Simon A Levin
Journal of the Royal Society Interface, 2015, ⟨10.1098/rsif.2014.0893⟩
Journal articles hal-01237894v1
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Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, non-genetic instability and stress-induced adaptation

Rebecca H. Chisholm , Tommaso Lorenzi , Alexander Lorz , Annette K. Larsen , Luís Almeida et al.
2015
Preprints, Working Papers, ... hal-01111271v1
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Preface to Session 70 " Mathematical models and methods to investigate heterogeneity in cell and cell population biology

Loic Barbarroux , Jean Clairambault , Nick Cogan , Jan Elias , Shalla Hanson et al.
ICNAAM 2015 Session 70: "Mathematical models and methods to investigate heterogeneity in cell and cell population biology'', Organiser Session 70: Jean Clairambault, Sep 2015, Rhodes, Greece
Conference papers hal-01249244v1
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Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies

Alexander Lorz , Tommaso Lorenzi , Michael E. Hochberg , Jean Clairambault , Benoît Perthame et al.
ESAIM: Mathematical Modelling and Numerical Analysis, 2013, pp.23. ⟨10.1051/m2an/2012031⟩
Journal articles hal-00714274v1

A mathematical model to study the impact of intra-tumour heterogeneity on anti-tumour CD8+ T cell immune response

Emma Leschiera , Tommaso Lorenzi , Shensi Shen , Luis Almeida , Chloe Audebert et al.
Journal of Theoretical Biology, 2022, 538, pp.111028. ⟨10.1016/j.jtbi.2022.111028⟩
Journal articles hal-03673890v1