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Infiltrating and peripheral immune cell analysis in advanced gastric cancer according to the Lauren classification and its prognostic significance

Simon Pernot , Magali Terme , Nina Radosevic-Robin , Florence Castan , Cecile Badoual et al.
Gastric Cancer, 2019, ⟨10.1007/s10120-019-00983-3⟩
Journal articles hal-02384138v1

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

Fanny Chalmin , Sylvain Ladoire , Grégoire Mignot , Julie Vincent , Mélanie Bruchard et al.
Journal of Clinical Investigation, 2020, ⟨10.1172/JCI40483⟩
Journal articles hal-03030322v1

PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

Magalie Dosset , Thaiz Rivera Vargas , Anais Lagrange , Romain Boidot , Frédérique Vegran et al.
OncoImmunology, 2018, 7 (6), pp.e1433981. ⟨10.1080/2162402X.2018.1433981⟩
Journal articles hal-01928503v1

Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer

Mercedes Tomé , Angela Pappalardo , Fabienne Soulet , José Javier López , Jone Olaizola et al.
Cancer Research, 2019, 79 (19), pp.5008-5021. ⟨10.1158/0008-5472.CAN-19-0086⟩
Journal articles hal-02407117v1
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Development of a novel highly anti-proliferative family of gold complexes: Au(I)-phosphoniumphosphines

Benjamin Rousselle , Florence Bouyer , Jérôme Bayardon , Myriam Laly , François Ghiringhelli et al.
Dalton Transactions, 2021, 50, pp.4880-4889. ⟨10.1039/D0DT03708G⟩
Journal articles hal-03292599v1
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CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner.

François Ghiringhelli , Cédric Ménard , Magali Terme , Caroline Flament , Julien Taieb et al.
Journal of Experimental Medicine, 2007, 202 (8), pp.1075-85. ⟨10.1084/jem.20051511⟩
Journal articles pasteur-00020140v1

Temozolomide Plus Bevacizumab in Elderly Patients with Newly Diagnosed Glioblastoma and Poor Performance Status: An ANOCEF Phase II Trial (ATAG)

Germán Reyes-Botero , Stéphanie Cartalat-Carel , Olivier Chinot , Maryline Barrie , Luc Taillandier et al.
Oncologist, 2018, 23 (5), pp.524-e44. ⟨10.1634/theoncologist.2017-0689⟩
Journal articles hal-01727451v1
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Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients

Marion Picard , Satoru Yonekura , Karolina Slowicka , Ioanna Petta , Conrad Rauber et al.
Cell Death and Differentiation, 2021, 28 (5), pp.1532-1547. ⟨10.1038/s41418-020-00684-w⟩
Journal articles hal-03682003v1
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Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage

Aurélie Fluckiger , Romain Daillere , Mohamed Sassi , Barbara S Sixt , Peng Liu et al.
Science, 2020, 369 (6506), pp.936-942. ⟨10.1126/science.aax0701⟩
Journal articles inserm-02923397v1

Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth.

Alice Hervieu , Cédric Rébé , Frédérique Végran , Fanny Chalmin , Mélanie Bruchard et al.
Journal of Investigative Dermatology, 2013, 133 (2), pp.499-508. ⟨10.1038/jid.2012.273⟩
Journal articles inserm-00857892v1
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Contribution of IL-17-producing {gamma}{delta} T cells to the efficacy of anticancer chemotherapy.

Yuting Ma , Laetitia Aymeric , Clara Locher , Stephen R Mattarollo , Nicolas F Delahaye et al.
Journal of Experimental Medicine, 2011, 208 (3), pp.491-503. ⟨10.1084/jem.20100269⟩
Journal articles pasteur-00576679v1

Etude LYMPHOREC. Réponse immunitaire intra-tumorale à la radiothérapie préopératoire pour des cancers du rectum de stades II-III: nouveau paramètre pronostic de la survie des patients

Céline Mirjolet , Céline Charon-Barra , Sylvain Ladoire , Francine Arbez-Gindre , Mélanie Gauthier et al.
9e Forum du Cancéropôle du Grand Est, Nov 2015, Strasbourg, France
Conference papers hal-01241779v1

Impact of proton therapy on antitumor immune response

Céline Mirjolet , Anaïs Nicol , Emeric Limagne , Carole Mura , Corentin Richard et al.
Scientific Reports, 2021, 11 (1), pp.13444. ⟨10.1038/s41598-021-92942-1⟩
Journal articles hal-03323273v1
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Deep learning for colon cancer histopathological images analysis

Amina Ben Hamida , Maxime Devanne , Jonathan Weber , Caroline Truntzer , Valentin Derangère et al.
Computers in Biology and Medicine, 2021, ⟨10.1016/j.compbiomed.2021.104730⟩
Journal articles hal-03321646v1
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NLRP3 controls ATM activation in response to DNA damage

Mélanie Bodnar-Wachtel , Anne-Laure Huber , Julie Gorry , Sabine Hacot , Laetitia Gerossier et al.
Preprints, Working Papers, ... hal-03093041v1

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.

François Ghiringhelli , Lionel Apetoh , Antoine Tesniere , Laetitia Aymeric , Yuting Ma et al.
Nature Medicine, 2009, epub ahead of print. ⟨10.1038/nm.2028⟩
Journal articles hal-00419823v1

Liver X Receptor β activation induces pyroptosis of human and murine colon cancer cells

Valentin Derangere , Angélique Chevriaux , F Courtaut , Melanie Bruchard , H Berger et al.
Cell Death and Differentiation, 2014, 21, pp.1914 - 1924
Journal articles hal-02300412v1

Correction: SNP Array Analysis Reveals Novel Genomic Abnormalities Including Copy Neutral Loss of Heterozygosity in Anaplastic Oligodendrogliomas

Ahmed Idbaih , François Ducray , Caroline Dehais , Célia Courdy , Catherine Carpentier et al.
Journal articles hal-03025087v1

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.

Lionel Apetoh , François Ghiringhelli , Antoine Tesniere , Michel Obeid , Carla Ortiz et al.
Nature Medicine, 2007, 13 (9), pp.1050-9. ⟨10.1038/nm1622⟩
Journal articles hal-00316924v1
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SNP array analysis reveals novel genomic abnormalities including copy neutral loss of heterozygosity in anaplastic oligodendrogliomas

Ahmed Idbaih , François Ducray , Caroline Dehais , Célia Courdy , Catherine Carpentier et al.
PLoS ONE, 2012, 7 (10), pp.e45950. ⟨10.1371/journal.pone.0045950⟩
Journal articles hal-00911465v1

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

Melanie Bruchard , Gregoire Mignot , Valentin Derangere , Fanny Chalmin , Angélique Chevriaux et al.
Nature Medicine, 2013, 19, pp.57 - 64. ⟨10.1038/nm.2999⟩
Journal articles hal-00919371v1

Tumor destruction using electrochemotherapy followed by CpG oligodeoxynucleotide injection induces distant tumor responses.

Stephan Roux , Claire Bernat , Bassim Al-Sakere , François Ghiringhelli , Paule Opolon et al.
Cancer Immunology, Immunotherapy, 2008, 57 (9), pp.1291-300. ⟨10.1007/s00262-008-0462-0⟩
Journal articles istex hal-00319924v1

Detection of KRAS, NRAS and BRAF somatic mutations in circulating tumor DNA using two assays of Next Generation Sequencing (NGS) for patients with metastatic colorectal cancer

Alexandre Harlé , Romain Boidot , Marie Rouyer , Sandy Chevrier , Vincent Massard et al.
4ème Colloque Inter-Régional Grand-Est de Recherche Translationnelle en Oncologie, Oncotrans 2015, Jun 2015, Dijon, France
Conference papers hal-01241774v1
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Prognostic value of angiopoietin-2 for death risk stratification in patients with metastatic colorectal carcinoma.

Marine Jary , Dewi Vernerey , Thierry Lecomte , Erion Dobi , François Ghiringhelli et al.
Cancer Epidemiology, Biomarkers and Prevention, 2015, 24 (3), pp.603-12. ⟨10.1158/1055-9965.EPI-14-1059⟩
Journal articles inserm-01139951v1

Response to first line chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer

Courèche-Guillaume Kaderbhai , Corentin Richard , Anne Aarnink , Sandra Ortiz-Cuaran , Pascal Foucher et al.
OncoImmunology, 2017, 6 (9), pp.e1339856. ⟨10.1080/2162402X.2017.1339856⟩
Journal articles hal-01694057v1
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Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

Maria Paula Roberti , Satoru Yonekura , Connie P. M. Duong , Marion Picard , Gladys Ferrere et al.
Nature Medicine, 2020, 26 (6), p. 919-931. ⟨10.1038/s41591-020-0882-8⟩
Journal articles hal-03313676v1

Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors

Trinh-Le-Vi Kieu , Léa Pierre , Valentin Derangère , Sabrina Perrey , Caroline Truntzer et al.
Cell Death and Disease, 2022, 13 (9), pp.758. ⟨10.1038/s41419-022-05209-6⟩
Journal articles hal-03972007v1

Chemoimmunotherapy of Tumors: Cyclophosphamide Synergizes with Exosome Based Vaccines

Julien Taieb , Nathalie Chaput , Noël Schartz , Stéphan Roux , Sophie Novault et al.
Journal of Immunology, 2006, 176 (5), pp.2722-2729. ⟨10.4049/jimmunol.176.5.2722⟩
Journal articles pasteur-03360098v1
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Immunodynamics of explanted human tumors for immuno-oncology

Agathe Dubuisson , Jean Eudes Fahrner , Anne Gaëlle Goubet , Safae A. Terrisse , Nicolas Voisin et al.
EMBO Molecular Medicine, 2021, 13 (1), ⟨10.15252/emmm.202012850⟩
Journal articles hal-03127487v1
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Red wine extract disrupts Th17 lymphocyte differentiation in a colorectal cancer context

Pauline Chalons , Flavie Courtaut , Emeric Limagne , Fanny F Chalmin , Emma Cantos-Villar et al.
Molecular Nutrition and Food Research, 2020, 64 (11), pp.1901286. ⟨10.1002/mnfr.201901286⟩
Journal articles hal-03033795v1