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Inhibition of PI3K pathway increases immune infiltrate in muscle-invasive bladder cancer

Edith Borcoman , Philippe de La Rochere , Wilfrid Richer , Sophie Vacher , Walid Chemlali et al.
OncoImmunology, 2019, 8 (5), pp.e1581556. ⟨10.1080/2162402X.2019.1581556⟩
Journal articles hal-02336158v1

Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines.

Hervé Wallerand , Ying Cai , Zev A Wainberg , Isla Garraway , Isabelle Lascombe et al.
Urologic Oncology: Seminars and Original Investigations, 2010, 28 (2), pp.180-188. ⟨10.1016/j.urolonc.2008.09.041⟩
Journal articles hal-00485120v1
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Role of a Kinesin Motor in Cancer Cell Mechanics

Kalpana Mandal , Katarzyna Pogoda , Satabdi Nandi , Samuel Mathieu , Amal Kasri et al.
Nano Letters, 2019, 19, pp.7691-7702. ⟨10.1021/acs.nanolett.9b02592⟩
Journal articles hal-02332465v1
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A Parent-of-Origin Effect Impacts the Phenotype in Low Penetrance Retinoblastoma Families Segregating the c.1981C>T/p.Arg661Trp Mutation of RB1

Philippine Eloy , Catherine Dehainault , Meriem Sefta , Isabelle Aerts , François Doz et al.
PLoS Genetics, 2016, 12 (2), pp.e1005888. ⟨10.1371/journal.pgen.1005888⟩
Journal articles hal-01286009v1
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Design of a randomized controlled phase III study of dose dense methotrexate, vinblastine, doxorubicin and cisplatin (dd-MVAC) or gemcitabine and cisplatin (GC) as peri-operative chemotherapy for patients with locally advanced transitional cell cancer of the bladder. The French GETUG/AFU V05 VESPER trial

Christian Pfister , Valentin Harter , Yves Allory , François Radvanyi , Stéphane Culine et al.
Contemporary Clinical Trials Communications, 2020, 17, pp.100536. ⟨10.1016/j.conctc.2020.100536⟩
Journal articles hal-02909542v1
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PPARγ is a tumor suppressor in basal bladder tumors offering new potential therapeutic opportunities

Laure Coutos-Thévenot , Syrine Beji , Hélène Neyret-Kahn , Quentin Pippo , Jacqueline Fontugne et al.
Preprints, Working Papers, ... hal-03424976v1
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Integrative Modelling of the Influence of MAPK Network on Cancer Cell Fate Decision

Luca Grieco , Laurence Calzone , Isabelle Bernard-Pierrot , François Radvanyi , Brigitte Kahn-Perlès et al.
PLoS Computational Biology, 2013, 9 (10), pp.e1003286. ⟨10.1371/journal.pcbi.1003286⟩
Journal articles inserm-02152259v1
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Identification of new driver and passenger mutations within APOBEC-induced hotspot mutations in bladder cancer

Ming-Jun Shi , Xiang-Yu Meng , Jacqueline Fontugne , Chun-Long Chen , François Radvanyi et al.
Genome Medicine, 2020, 12 (1), ⟨10.1186/s13073-020-00781-y⟩
Journal articles hal-03015020v1

LICORN: learning cooperative regulation networks from gene expression data.

Mohamed Elati , Pierre Neuvial , Monique Bolotin-Fukuhara , Emmanuel Barillot , François Radvanyi et al.
Bioinformatics, 2007, 23 (18), pp.2407-14. ⟨10.1093/bioinformatics/btm352⟩
Journal articles hal-00192537v1
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A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

Jing Liu , Daniela Ottaviani , Meriem Sefta , Céline Desbrousses , Elodie Chapeaublanc et al.
Nature Communications, 2021, 12 (1), pp.1-20. ⟨10.1038/s41467-021-25792-0⟩
Journal articles hal-03374490v1

Tertiary lymphoid structures marker CXCL13 is associated with better survival for patients with advanced-stage bladder cancer treated with immunotherapy

Clarice Groeneveld , Jacqueline Fontugne , Luc Cabel , Isabelle Bernard-Pierrot , François Radvanyi et al.
European Journal of Cancer, 2021, 148, pp.181-189. ⟨10.1016/j.ejca.2021.01.036⟩
Journal articles hal-03453779v1

A Meta-Analysis of the Relationship between FGFR3 and TP53 Mutations in Bladder Cancer

Yann Neuzillet , Xavier Paoletti , Slah Ouerhani , Pierre Mongiat-Artus , Hany Soliman et al.
PLoS ONE, 2012, 7 (12), ⟨10.1371/journal.pone.0048993⟩
Journal articles hal-01358546v1

Identification of targeted therapy for an aggressive subgroup of muscle-invasive bladder cancers

Thierry Lebret , Yann Neuzillet , Nadine Houédé , Sandra Rebouissou , Isabelle Bernard-Pierrot et al.
Molecular & Cellular Oncology, 2015, 2 (4), pp.e999507. ⟨10.1080/23723556.2014.999507⟩
Journal articles hal-01904887v1
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Spatial normalization of array-CGH data.

Pierre Neuvial , Philippe Hupé , Isabel Brito , Stéphane Liva , Elodie Manié et al.
BMC Bioinformatics, 2006, 7, pp.264. ⟨10.1186/1471-2105-7-264⟩
Journal articles inserm-00089910v1

VAMP: Visualization and analysis of array-CGH, transcriptome and other molecular profiles

Philippe La Rosa , Eric Viara , Philippe Hupé , Gaëlle Pierron , Stéphane Liva et al.
Bioinformatics, 2006, 22 (17), pp.2066-2073. ⟨10.1093/bioinformatics/btl359⟩
Journal articles hal-01199867v1

ITTACA: a new database for integrated tumor transcriptome array and clinical data analysis

Adil El Filali , Séverine Lair , Catia Verbeke , Philippe La Rosa , François Radvanyi et al.
Nucleic Acids Research, 2006, 34 (90001), pp.D613-D616. ⟨10.1093/nar/gkj022⟩
Journal articles hal-03225608v1

Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors

Tom Baladi , Jessy Aziz , Florent Dufour , Valentina Abet , Véronique Stoven et al.
Bioorganic and Medicinal Chemistry, 2018, 26 (20), pp.5510-5530. ⟨10.1016/j.bmc.2018.09.031⟩
Journal articles hal-01986358v1

A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis.

Elisabeth Remy , Sandra Rebouissou , Claudine Chaouiya , Andrei Zinovyev , François Radvanyi et al.
Cancer Research, 2015, 75 (19), pp.4042-52
Journal articles hal-01285974v1
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TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer

Florent Dufour , Linda Silina , Hélène Neyret-Kahn , Aura Moreno-Vega , Clémentine Krucker et al.
British Journal of Cancer, 2019, 120 (5), pp.555-564. ⟨10.1038/s41416-019-0397-6⟩
Journal articles hal-02340153v1
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STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells

Laia Richart , Eleonora Lapi , Vera Pancaldi , Mirabai Cuenca-Ardura , Enrique Carrillo-De-Santa Pau et al.
Nucleic Acids Research, 2021, ⟨10.1093/nar/gkab864⟩
Journal articles hal-03385084v1
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IGF1R activation and the in vitro antiproliferative efficacy of IGF1R inhibitor are inversely correlated with IGFBP5 expression in bladder cancer

Yann Neuzillet , Elodie Chapeaublanc , Clémentine Krucker , Leanne de Koning , Thierry Lebret et al.
BMC Cancer, 2017, 17 (1), pp.636. ⟨10.1186/s12885-017-3618-5⟩
Journal articles hal-01587434v1

Gene List significance at-a-glance with GeneValorization.

Bryan Brancotte , Anne Biton , Isabelle Bernard-Pierrot , François Radvanyi , Fabien Reyal et al.
Bioinformatics, 2011, 27 (8), pp.1187-9. ⟨10.1093/bioinformatics/btr073⟩
Journal articles inria-00627865v1

Multilayer spectrum of intratumoral heterogeneity in basal bladder cancer

Nanor Sirab , Damien Drubay , Pascale Maillé , Tatiana G. Popova , Carine Ngo et al.
Journal of Pathology, 2022, 256 (1), pp.108-118. ⟨10.1002/path.5813⟩
Journal articles hal-03524517v1
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Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis.

Eric Letouzé , Yves Allory , Marc A. Bollet , François Radvanyi , Frédéric Guyon et al.
Genome Biology, 2010, 11 (7), pp.R76. ⟨10.1186/gb-2010-11-7-r76⟩
Journal articles inserm-00539062v1
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Independent Component Analysis for Unraveling the Complexity of Cancer Omics Datasets

Nicolas Sompairac , Petr V Nazarov , Urszula Czerwinska , Laura Cantini , Anne Biton et al.
International Journal of Molecular Sciences, 2019, 20 (18), pp.4414. ⟨10.3390/ijms20184414⟩
Journal articles hal-02343412v1

Triple extraction method enables high quality mass spectrometry‐based proteomics and phospho‐proteomics for eventual multi‐omics integration studies

Virginia Sanchez‐quiles , Ming‐jun Shi , Florent Dingli , Clémentine Krucker , Damarys Loew et al.
Proteomics, 2021, 21 (16), pp.2000303. ⟨10.1002/pmic.202000303⟩
Journal articles hal-03453774v1
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SegCorr a statistical procedure for the detection of genomic regions of correlated expression

Eleni Ioanna Delatola , Emilie Lebarbier , Tristan Mary-Huard , François Radvanyi , Stéphane Robin et al.
BMC Bioinformatics, 2017, 18 (1), pp.333. ⟨10.1186/s12859-017-1742-5⟩
Journal articles inserm-02059501v1
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A Consensus Molecular Classification of Muscle-invasive Bladder Cancer

Mauro a A Castro , Mattias Aine , Hikmat Al-Ahmadie , Yves Allory , Joaquim Bellmunt et al.
European Urology, 2020, 77 (4), pp.420-433. ⟨10.1016/j.eururo.2019.09.006⟩
Journal articles hal-03104379v1
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Occupational exposure to polycyclic aromatic hydrocarbons influenced neither the frequency nor the spectrum of FGFR3 mutations in bladder urothelial carcinoma.

Ashraf A. Bakkar , Yves Allory , Yuriko Iwatsubo , Sixtina Gil Diez de Medina , Pascale Maille et al.
Molecular Carcinogenesis, 2010, 49 (1), pp.25-31. ⟨10.1002/mc.20573⟩
Journal articles istex inserm-00459324v1
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An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers

Mélanie Mahé , Florent Dufour , Hélène Neyret-Kahn , Aura Moreno-Vega , Claire Béraud et al.
EMBO Molecular Medicine, 2018, 10 (4), pp.e8163. ⟨10.15252/emmm.201708163⟩
Journal articles hal-02066552v1