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Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation.
Gilles Labesse
,
Khaled Benkali
,
Isabelle Salard-Arnaud
,
Anne-Marie Gilles
,
Hélène Munier-Lehmann
et al.
Journal articles
pasteur-00589535v1
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The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria.
Annemarie Wehenkel
,
Pablo Fernandez
,
Marco Bellinzoni
,
Vincent Catherinot
,
Nathalie Barilone
et al.
Journal articles
istex
pasteur-03144516v1
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6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.
Claire Amiable
,
Julie Paoletti
,
Ahmed Haouz
,
André Padilla
,
Gilles Labesse
et al.
Journal articles
pasteur-01483767v1
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Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes.
Hélène Munier-Lehmann
,
Alain Chaffotte
,
Sylvie Pochet
,
Gilles Labesse
Journal articles
pasteur-00167069v1
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Crystal Structure of MabA from Mycobacterium tuberculosis, a Reductase involved in Long-chain Fatty Acid Biosynthesis
Martin Cohen-Gonsaud
,
Stéphanie Ducasse
,
Francois Hoh
,
Didier Zerbib
,
Gilles Labesse
et al.
Journal articles
istex
hal-02359522v1
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Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding
Melanie Schneider
,
Vanessa Delfosse
,
Muriel Gelin
,
Marina Grimaldi
,
Meritxell Granell
et al.
Journal articles
hal-03795558v1
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Nucleoside analogues as inhibitors of thymidylate kinases: possible therapeutic applications.
Sylvie Pochet
,
Laurence Dugué
,
Dominique Douguet
,
Gilles Labesse
,
Hélène Munier-Lehmann
et al.
Journal articles
istex
pasteur-00166196v1
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Rho-GTPase-activating Protein Interacting with Cdc-42-interacting Protein 4 Homolog 2 (Rich2)
F. Raynaud
,
Enora Moutin
,
Vincent Compan
,
Caroline Clerté
,
Nathalie Bouquier
et al.
Journal articles
hal-03674325v1
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N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1.
Claire Amiable
,
Sylvie Pochet
,
André Padilla
,
Gilles Labesse
,
Pierre-Alexandre Kaminski
et al.
Journal articles
pasteur-01472730v1
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A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti-Toxoplasma and Anti-Plasmodium Activities Controls Acute and Chronic Toxoplasma Infection in Mice
Delphine Jublot
,
Pierre Cavaillès
,
Salima Kamche
,
Denise Francisco
,
Diana Fontinha
et al.
Journal articles
hal-03818209v1
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A new autosomal dominant eye and lung syndrome linked to mutations in TIMP3 gene
Isabelle Meunier
,
Béatrice Bocquet
,
Gilles Labesse
,
Christina Zeitz
,
Sabine Defoort-Dhellemmes
et al.
Journal articles
hal-01824596v1
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Characterization of the mechanisms controlling Greatwall activity.
Suzanne Vigneron
,
Aicha Gharbi-Ayachi
,
Anne-Aurélie Raymond
,
Andrew Burgess
,
Jean-Claude Labbé
et al.
Journal articles
hal-00649525v1
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Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its Sequence -Structure -Function analysis
Cécile Fleury
,
Jérôme Gracy
,
Marie-Françoise Gautier
,
Jean-Luc Pons
,
Jean-François Dufayard
et al.
Journal articles
hal-02112505v1
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Structural characterization of the mammalian deoxynucleotide N-hydrolase Rcl and its stabilizing interactions with two inhibitors.
Yinshan Yang
,
André Padilla
,
Chi Zhang
,
Gilles Labesse
,
Pierre-Alexandre Kaminski
et al.
Journal articles
pasteur-03726707v1
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Screening and In Situ Synthesis Using Crystals of a NAD Kinase Lead to a Potent Antistaphylococcal Compound
Muriel Gelin
,
Guillaume Poncet-Montange
,
Liliane Assairi
,
Laurence Morellato
,
Valérie Huteau
et al.
Journal articles
hal-02648096v1
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Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity
Sébastien Sagnol
,
Yinshan Yang
,
Yannick Bessin
,
Frédéric Allemand
,
Ilona Hapkova
et al.
Journal articles
hal-02543654v1
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The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling.
Hiba El Hajj
,
Emmanuelle Demey
,
Joël Poncet
,
Maryse Lebrun
,
Bo Wu
et al.
Journal articles
istex
hal-00167426v1
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Internal point mutations of the capsid modify the serotype of Rice yellow mottle virus.
Eugénie Hébrard
,
Agnès Pinel-Galzi
,
Vincent Catherinot
,
Gilles Labesse
,
Christophe Brugidou
et al.
Journal articles
hal-00168833v1
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Structural and nucleotide-binding properties of YajQ and YnaF, two Escherichia coli proteins of unknown function
Cosmin Saveanu
,
Simona Miron
,
Tudor Borza
,
Constantin T. Craescu
,
Gilles Labesse
et al.
Journal articles
pasteur-01404701v1
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ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity.
Gilles Labesse
,
Muriel Gelin
,
Yannick Bessin
,
Maryse Lebrun
,
Julien Papoin
et al.
Journal articles
hal-00373662v1
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A dominant mutation in MAPKAPK3 , an actor of p38 signaling pathway, causes a new retinal dystrophy involving Bruch's membrane and retinal pigment epithelium
Isabelle Meunier
,
Guy Lenaers
,
Beatrice Bocquet
,
Corinne Baudoin
,
Camille Piro-Megy
et al.
Journal articles
hal-01882151v1
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An oligomeric switch controls the Mrr-induced SOS response in E. coli
Anaïs C Bourges
,
Oscar E Torres Montaguth
,
Wubishet Tadesse
,
Gilles Labesse
,
Abram Aertsen
et al.
Journal articles
hal-03015076v1
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New compounds for the treatment and/or prevention of parasitic diseases and method of production of thereof
Denis Sereno
,
Gilles Labesse
,
Jean-François Guichon
,
Corinne Loeuillet
,
Deborah Gracia
et al.
France, Patent n° : EP N° 13177129.7. 2013
Patents
hal-00918009v1
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Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes.
Vanessa Delfosse
,
Marina Grimaldi
,
Jean-Luc Pons
,
Abdelhay Boulahtouf
,
Albane Le Maire
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, epub ahead of print. ⟨10.1073/pnas.1203574109⟩
Journal articles
inserm-00726779v1
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Phosphodeoxyribosyltransferases: designed enzymes for deoxyribonucleotide synthesis.
Pierre-Alexandre Kaminski
,
Gilles Labesse
Journal articles
pasteur-00796440v1
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The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an Arpp19/PP2A-B55 feedback loop
Jean Claude Labbé
,
Suzanne Vigneron
,
Francisca Méchali
,
Perle Robert
,
Sylvain Roque
et al.
Journal articles
hal-03263787v1
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Structure-based design of NAD+ analogues targeting bacterial NAD kinases, promising targets for new antibiotics
Rahila Rahimova
,
Pauline Nogaret
,
Valérie Huteau
,
Clarisse Leseigneur
,
Muriel Gelin
et al.
The Biochemistry Global Summit, 25th IUBMB Congress, 46th FEBS Congress, 15th PABMB Congress, Portuguese Biochemical Society (SPB); IUBMB; FEBS; PABMB, Jul 2022, Lisbon, Portugal. pp.24, ⟨10.1002/2211-5463.13442⟩
Conference papers
hal-03854164v1
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Probing Protein Interaction Networks by Combining MS-Based Proteomics and Structural Data Integration
Guillaume Postic
,
Julien Marcoux
,
Victor Reys
,
Jessica Andreani
,
Yves Vandenbrouck
et al.
Journal articles
hal-02571410v1
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Non-classical ligand-independent regulation of Go protein by an orphan Class C GPCR
Mariana Hajj
,
Teresa de Vita
,
Claire Vol
,
Charlotte Renassia
,
Jean-Charles Bologna
et al.
Journal articles
hal-02396282v1
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A 20-amino acid module of protein kinase C{epsilon} involved in translocation and selective targeting at cell-cell contacts.
Barthélémy Diouf
,
Alejandra Collazos
,
Gilles Labesse
,
Françoise Macari
,
Armelle Choquet
et al.
Journal articles
hal-00423750v1
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