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Glycerol suppresses glucose consumption in trypanosomes through metabolic contest

Stefan Allmann , Marion Wargnies , Nicolas Plazolles , Edern Cahoreau , Marc Biran et al.
Plos Biology, 2021, 19 (8), ⟨10.1371/journal.pbio.3001359⟩
Journal articles hal-03365992v1
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Gluconeogenesis is essential for trypanosome development in the tsetse fly vector

Marion Wargnies , Eloise Bertiaux , Edern Cahoreau , Nicole Ziebart , Aline Crouzols et al.
PLoS Pathogens, 2018, 14 (12), pp.e1007502. ⟨10.1371/journal.ppat.1007502⟩
Journal articles pasteur-01963538v1
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Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline

Oriana Villafraz , Marc Biran , Erika Pineda , Nicolas Plazolles , Edern Cahoreau et al.
PLoS Pathogens, 2021, 17 (3), pp.e1009204. ⟨10.1371/journal.ppat.1009204⟩
Journal articles hal-03366686v1

Sialidases play a key role in infection and anaemia in Trypanosoma congolense animal trypanosomiasis.

Virginie Coustou , Nicolas Plazolles , Fabien Guegan , Théo Baltz
Cellular Microbiology, 2012, 14 (3), pp.431-45. ⟨10.1111/j.1462-5822.2011.01730.x⟩
Journal articles hal-00675699v1
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Ablation of Succinate Production from Glucose Metabolism in the Procyclic Trypanosomes Induces Metabolic Switches to the Glycerol 3-Phosphate/Dihydroxyacetone Phosphate Shuttle and to Proline Metabolism

Charles Ebikeme , Jane Hubert , Marc Biran , Gilles Gouspillou , Pauline Morand et al.
Journal of Biological Chemistry, 2010, 285 (42), pp.32312 - 32324. ⟨10.1074/jbc.M110.124917⟩
Journal articles hal-02655484v1

Complete in vitro life cycle of Trypanosoma congolense: development of genetic tools.

Virginie Coustou , Fabien Guegan , Nicolas Plazolles , Théo Baltz
PLoS Neglected Tropical Diseases, 2010, 4 (3), pp.e618. ⟨10.1371/journal.pntd.0000618⟩
Journal articles hal-00522686v1
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Metabolic selection of a homologous recombination-mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase

Marion Wargnies , Nicolas Plazolles , Robin Schenk , Oriana Villafraz , Jean-William Dupuy et al.
Journal of Biological Chemistry, 2021, 296, pp.100548. ⟨10.1016/j.jbc.2021.100548⟩
Journal articles hal-03366694v1

Erythrophagocytosis of desialylated red blood cells is responsible for anaemia during Trypanosoma vivax infection.

Fabien Guegan , Nicolas Plazolles , Théo Baltz , Virginie Coustou
Cellular Microbiology, 2013, 15(8), pp.1285-303
Journal articles hal-01101373v1
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Glycerol, a possible new player in the biology of trypanosomes

Frédéric Bringaud , Nicolas Plazolles , Erika Pineda , Corinne Asencio , Oriana Villafraz et al.
PLoS Pathogens, 2021, 17, ⟨10.1371/journal.ppat.1010035⟩
Journal articles hal-03851321v1

Identification of trans-sialidases as a common mediator of endothelial cell activation by African trypanosomes.

Zeinab Ammar , Nicolas Plazolles , Théo Baltz , Virginie Coustou
PLoS Pathogens, 2012, 9(10), pp.e1003710
Journal articles hal-01101372v1

Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes.

Loïc Rivière , Patrick Moreau , Stefan Allmann , Matthias Hahn , Marc Biran et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (31), pp.12694-9. ⟨10.1073/pnas.0903355106⟩
Journal articles hal-00426334v1
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De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions

Yoann Millerioux , Muriel Mazet , Guillaume Bouyssou , Stefan Allmann , Tiila-Riikka Kiema et al.
PLoS Pathogens, 2018, 14 (5), pp.e1007116. ⟨10.1371/journal.ppat.1007116⟩
Journal articles pasteur-01849809v1
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Metabolic selection of a homologous recombination-mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase

Marion Wargnies , Nicolas Plazolles , Robin Schenk , Oriana Villafraz , Jean-William Dupuy et al.
Journal of Biological Chemistry, 2021, 296, pp.100548. ⟨10.1016/j.jbc.2021.100548⟩
Journal articles hal-03216701v1
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Glycerol, a possible new player in the biology of trypanosomes

Frédéric Bringaud , Nicolas Plazolles , Erika Pineda , Corinne Asencio , Oriana Villafraz et al.
PLoS Pathogens, 2021, 17 (12), pp.e1010035. ⟨10.1371/journal.ppat.1010035⟩
Journal articles hal-03920913v1

Glucose-induced remodeling of intermediary and energy metabolism in procyclic Trypanosoma brucei.

Virginie Coustou , Marc Biran , Marc Breton , Fabien Guegan , Loïc Rivière et al.
Journal of Biological Chemistry, 2008, 283 (24), pp.16342-54. ⟨10.1074/jbc.M709592200⟩
Journal articles hal-00318595v1