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High-throughput screening for extracellular inhibitors of the FLT3 receptor tyrosine kinase reveals chemically diverse and druggable negative allosteric modulators
Romain Hany
,
Jean-Philippe Leyris
,
Guillaume Bret
,
Sylvie Mallié
,
Chamroeun Sar
et al.
Journal articles
hal-03747971v1
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Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3-Mutated Gliomas Recreate the Patient Tumor Complexity
Anne-Florence Blandin
,
Aurélie Durand
,
Marie Litzler
,
Aurélien Tripp
,
Eric Guérin
et al.
Journal articles
hal-03098718v1
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Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians
Emeline Houël
,
Flore Nardella
,
Valérie Jullian
,
Alexis Valentin
,
Catherine Vonthron-Sénécheau
et al.
Journal articles
hal-01313006v1
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Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia
Pierre Regenass
,
Dayana Abboud
,
Francois Daubeuf
,
Christine Lehalle
,
Patrick Gizzi
et al.
Journal articles
hal-02366281v1
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Nile Red-Based GPCR Ligands as Ultrasensitive Probes of the Local Lipid Microenvironment of the Receptor
Fabien Hanser
,
Claire Marsol
,
Christel Valencia
,
Pascal Villa
,
Andrey S Klymchenko
et al.
Journal articles
hal-03437257v1
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A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor
Christel Valencia
,
Céline Dujet
,
Jean-François Margathe
,
Xavier Iturrioz
,
Thomas Roux
et al.
Journal articles
hal-02153692v1
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LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism
Marie-Céline Frantz
,
Lucie P. Pellissier
,
Elsa Pflimlin
,
Stéphanie Loison
,
Jorge Gandía
et al.
Journal articles
hal-02366272v1
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Takamalaimë (Psidium acutangulum Mart ex. DC): understanding the use of an antimalarial traditional remedy from French Guiana
Emeline S Houël
,
Marie Fleury
,
Valérie Jullian
,
Catherine Vonthron-Sénécheau
,
Flore Nardella
et al.
Planta Medica, 80 (10), pp.797-797, 2014
Proceedings
hal-03278506v1
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Limitations in a frataxin knockdown cell model for Friedreich ataxia in a high-throughput drug screen.
Nadège Calmels
,
Hervé Seznec
,
Pascal Villa
,
Laurence Reutenauer
,
Marcel Hibert
et al.
Journal articles
inserm-00420798v1
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Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime
André-Guilhem Calas
,
Anne-Sophie Hanak
,
Nina Jaffré
,
Aurélie Nervo
,
José Dias
et al.
Journal articles
hal-03127255v1
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Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells
Maria Zeniou
,
Marie Fève
,
Samir Mameri
,
Jihu Dong
,
Christophe Salomé
et al.
Journal articles
hal-01223842v1
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A strategy to discover decoy chemokine ligands with an anti-inflammatory activity
Dayana Abboud
,
Francois Daubeuf
,
Quoc Tuan Do
,
Valérie Utard
,
Pascal Villa
et al.
Journal articles
hal-02193983v1
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Antiplasmodial and anti-inflammatory effects of an antimalarial remedy from the Wayana Amerindians, French Guiana: Takamalaimë (Psidium acutangulum Mart. ex DC., Myrtaceae)
Emeline S Houël
,
Marie Fleury
,
Guillaume Odonne
,
Flore Nardella
,
Geneviève Bourdy
et al.
Journal articles
hal-01152706v1
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Daunorubicin reduces MBNL1 titration by expanded CUG repeat RNA and rescues cardiac dysfunctions in a Drosophila model of myotonic dystrophy
M. Chakraborty
,
Chantal Sellier
,
Michel Ney
,
Pascal Villa
,
Nicolas Charlet-Berguerand
et al.
Journal articles
hal-03339524v1
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WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3– cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling
Wanyin Chen
,
Leonel Nguekeu Zebaze
,
Jihu Dong
,
Laëtitia Chezeau
,
Perrine Inquimbert
et al.
Journal articles
hal-02349611v1
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Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia
Pierre Regenass
,
Dayana Abboud
,
François Daubeuf
,
Christine Lehalle
,
Patrick Gizzi
et al.
Journal articles
hal-03563473v1
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Anti-Inflammatory, Antioxidant, and Wound-Healing Properties of Cyanobacteria from Thermal Mud of Balaruc-Les-Bains, France: A Multi-Approach Study
Justine Demay
,
Sébastien Halary
,
Adeline Knittel-Obrecht
,
Pascal Villa
,
Charlotte Duval
et al.
Journal articles
hal-03091030v1
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Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model
Martine Schmitt
,
Maud Bollenbach
,
Simona Nemska; Patrick Wagner
,
Guillaume Camelin
,
Francois Daubeuf
et al.
Molecules, In press
Journal articles
hal-03113242v1
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Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation
Maud Bollenbach
,
Eric Salvat
,
Francois Daubeuf
,
Patrick Wagner
,
Ipek Yalcin
et al.
Journal articles
hal-02323729v1
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Treating leishmaniasis in Amazonia, part 2: Multi-target evaluation of widely used plants to understand medicinal practices
Emeline S Houël
,
Marine Ginouves
,
Nadine Azas
,
Eliane Bourreau
,
Véronique Eparvier
et al.
Journal articles
hal-03678995v1
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Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model
Maud Bollenbach
,
Simona Nemska
,
Patrick Wagner
,
Guillaume Camelin
,
François Daubeuf
et al.
Journal articles
hal-03266504v1
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