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Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL
Pierre-Yves Dumas
,
Cécile Naudin
,
Séverine Martin-Lannerée
,
Brigitte Izac
,
Luana Casetti
et al.
Journal articles
hal-02385250v1
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Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3 -ITD Acute Myeloid Leukemia
Pierre-Yves Dumas
,
Arnaud Villacreces
,
Amélie Guitart
,
Ali El-Habhab
,
Layal Massara
et al.
Journal articles
hal-03455205v1
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L'hypoxie contribue à la quiescence et la chimiorésistance des cellules initiatrices de leucémie aigüe lymphoblastique
Arnaud Villacreces
Theses
tel-01044915v2
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Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence
Angela Ianniciello
,
Pierre-Yves Dumas
,
Claire Drullion
,
Amélie Guitart
,
Arnaud Villacreces
et al.
Journal articles
hal-02397191v1
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α-Tocopherol Acetate Attenuates Mitochondrial Oxygen Consumption and Maintains Primitive Cells within Mesenchymal Stromal Cell Population
Darija Loncaric
,
Laura Rodriguez
,
Christelle Debeissat
,
Nicolas Touya
,
Veronique Labat
et al.
Journal articles
hal-03366594v1
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Midostaurin resistance in FLT3-ITD acute myeloblastic leukemia: Fonctional genomic screening by Crispr-Cas9
Solène Fernandez
,
Matthieu Lewis
,
Amélie Guitart
,
Layal Massara*
,
Clémentine Fabres
et al.
26ème congrès du CHO, Oct 2019, presqu'ïle de Giens, France. 26 ème congrès CHO revue, 26, pp.88
Conference poster
hal-02402820v1
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Very low oxygen concentration (0.1%) reveals two FDCP-Mix cells subpopulations that differ by their cell cycling, differentiation and p27KIP1 expression
Vincent Praloran
,
Amélie Guitart
,
Christelle Debeissat
,
Francis Hermitte
,
Arnaud Villacreces
et al.
Journal articles
hal-00560771v1
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Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia
Jasmin Paris
,
Marcos Morgan
,
Joana Campos
,
Gary Spencer
,
Alena Shmakova
et al.
Journal articles
hal-02389825v1
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α-Tocopherol Acetate Attenuates Mitochondrial Oxygen Consumption and Maintains Primitive Cells within Mesenchymal Stromal Cell Population
Darija Loncaric
,
Laura Rodriguez
,
Christelle Debeissat
,
Nicolas Touya
,
Veronique Labat
et al.
Journal articles
hal-03376630v1
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CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia: CBL controls kinase expression
Romain Gioia
,
Claire Trégoat
,
Pierre-Yves Dumas
,
Valérie Lagarde
,
Valérie Prouzet-Mauléon
et al.
Journal articles
istex
hal-01883494v1
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Hypoxia regulates CD9 expression and dissemination of B lymphoblasts
Jérémie Rouger-Gaudichon
,
Elie Cousin
,
Helene Jakobczyk
,
Lydie Debaize
,
Anne-Gäelle Rio
et al.
Journal articles
hal-03888260v1
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Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia
Adeline Crinier
,
Pierre-Yves Dumas
,
Bertrand Escalière
,
Christelle Piperoglou
,
Laurine Gil
et al.
Journal articles
hal-03374456v1
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Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia
Adeline Crinier
,
Pierre-Yves Dumas
,
Bertrand Escaliere
,
Christelle Piperoglou
,
Laurine Gil
et al.
Journal articles
hal-03099198v1
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