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PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

Elodie Montaudon , Joanna Nikitorowicz-Buniak , Laura Sourd , Ludivine Morisset , Rania El Botty et al.
Nature Communications, 2020, 11, ⟨10.1038/s41467-020-17697-1⟩
Journal articles hal-02933439v1

H3K27me3 is a determinant of chemotolerance in triple-negative breast cancer

Justine Marsolier , Pacôme Prompsy , Adeline Durand , Anne-Marie Lyne , Camille Landragin et al.
2021
Preprints, Working Papers, ... hal-03417195v1
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Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

Valentina Boeva , Caroline Louis-Brennetot , Agathe Peltier , Simon Durand , Cecile Pierre-Eugene et al.
Nature Genetics, 2017, 49 (9), pp.1408-1413. ⟨10.1038/ng.3921⟩
Journal articles hal-01741718v1

STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma

Didier Surdez , Sakina Zaidi , Sandrine Grossetête , Karine Laud-Duval , Anna Sole Ferre et al.
Cancer Cell, 2021, 39 (6), pp.810-826.e9. ⟨10.1016/j.ccell.2021.04.001⟩
Journal articles hal-03882743v1
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Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy.

Abir Tadmouri , Shigeki Kiyonaka , Maud Barbado , Matthieu Rousset , Katell Fablet et al.
EMBO Journal, 2012, 31 (18), pp.3730-44. ⟨10.1038/emboj.2012.226⟩
Journal articles inserm-00757285v1

Contribution of resident and circulating precursors to tumor-infiltrating CD8 + T cell populations in lung cancer

Paul Gueguen , Christina Metoikidou , Thomas Dupic , Myriam Lawand , Christel Goudot et al.
Science Immunology, 2021, 6 (55), ⟨10.1126/sciimmunol.abd5778⟩
Journal articles hal-03877456v1
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CD44 regulates epigenetic plasticity by mediating iron endocytosis

Sebastian Müller , Fabien Sindikubwabo , Tatiana Cañeque , Anne Lafon , Antoine Versini et al.
Nature Chemistry, 2020, 12 (10), pp.929-938. ⟨10.1038/s41557-020-0513-5⟩
Journal articles hal-03365507v1

Early macrophage response to obesity encompasses Interferon Regulatory Factor 5 regulated mitochondrial architecture remodelling

L. Orliaguet , T. Ejlalmanesh , A. Humbert , R. Ballaire , M. Diedisheim et al.
Nature Communications, 2022, 13 (1), pp.5089. ⟨10.1038/s41467-022-32813-z⟩
Journal articles hal-03770463v1
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Limited Sensitivity of Circulating Tumor DNA Detection by Droplet Digital PCR in Non-Metastatic Operable Gastric Cancer Patients

Luc Cabel , Charles Decraene , Ivan Bièche , Jean-Yves Pierga , Mostefa Bennamoun et al.
Cancers, 2019, 11 (3), pp.396. ⟨10.3390/cancers11030396⟩
Journal articles hal-02147125v1

H3K27me3 is a determinant of chemotolerance in triple-negative breast cancer

Justine Marsolier , Pacôme Prompsy , Adeline Durand , Anne-Marie Lyne , Camille Landragin et al.
2021
Preprints, Working Papers, ... hal-03140117v1
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H3K27me3 conditions chemotolerance in triple-negative breast cancer

Justine Marsolier , Pacôme Prompsy , Adeline Durand , Anne-Marie Lyne , Camille Landragin et al.
Nature Genetics, 2022, 54, pp.459-468. ⟨10.1038/s41588-022-01047-6⟩
Journal articles hal-03851953v1
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Contribution of resident and circulating precursors to tumor-infiltrating CD8 + T cell populations in non-small cell lung cancer patients

Paul Gueguen , Christina Metoikidou , Thomas Dupic , Myriam Lawand , Christel Goudot et al.
2020
Preprints, Working Papers, ... hal-02988498v1

FLASH Irradiation Spares Lung Progenitor Cells and Limits the Incidence of Radio-induced Senescence

Charles Fouillade , Sandra Curras-Alonso , Lorena Giuranno , Eddy Quelennec , Sophie Heinrich et al.
Clinical Cancer Research, 2020, ⟨10.1158/1078-0432.CCR-19-1440⟩
Journal articles hal-03023336v1
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Trajectory and uniqueness of mutational signatures in yeast mutators

Sophie Loeillet , Mareike Herzog , Fabio Puddu , Patricia Legoix , Sylvain Baulande et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (40), pp.24947-24956. ⟨10.1073/pnas.2011332117⟩
Journal articles hal-02986885v1
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Epigenetic control of CD8+ T cell responsiveness to a-PD-1 by Suv39h1

Leticia Laura Niborski , Paul Gueguen , Mengliang Ye , Allan Thiolat , Rodrigo Nalio Ramos et al.
2020
Preprints, Working Papers, ... hal-03041343v1

CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas

Leticia Laura Niborski , Paul Gueguen , Mengliang Ye , Allan Thiolat , Rodrigo Nalio Ramos et al.
Nature Communications, 2022, 13 (1), pp.3739. ⟨10.1038/s41467-022-31504-z⟩
Journal articles hal-03877477v1
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A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

Jing Liu , Daniela Ottaviani , Meriem Sefta , Céline Desbrousses , Elodie Chapeaublanc et al.
Nature Communications, 2021, 12 (1), pp.1-20. ⟨10.1038/s41467-021-25792-0⟩
Journal articles hal-03374490v1
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Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape

Frédéric Mourcin , Léa Verdière , David Roulois , Rada Amin , Claire Lamaison et al.
Immunity, 2021, 54 (8), pp.1788-1806.e7. ⟨10.1016/j.immuni.2021.05.019⟩
Journal articles hal-03282989v1

Sulfiredoxin protects mice from lipopolysaccharide-induced endotoxic shock.

Anne-Gaëlle Planson , Gaël Palais , Kahina Abbas , Matthieu Gerard , Linhdavanh Couvelard et al.
Antioxidants and Redox Signaling, 2011, 14 (11), pp.2071-80. ⟨10.1089/ars.2010.3552⟩
Journal articles hal-00606130v1

CD44 regulates epigenetic plasticity by mediating iron endocytosis

Sebastian Müller , Fabien Sindikubwabo , Tatiana Cañeque , Anne Lafon , Antoine Versini et al.
Nature Chemistry, 2020, 12 (10), pp.929-938. ⟨10.1038/s41557-020-0513-5⟩
Journal articles hal-04034917v1
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Combined transcript, proteome, and metabolite analysis of transgenic maize seeds engineered for enhanced carotenoid synthesis reveals pleotropic effects in core metabolism

Mathilde Decourcelle , Laura Perez-Fons , Sylvain Baulande , Sabine Steiger , Linhdavanh Couvelard et al.
Journal of Experimental Botany, 2015, 66 (11), pp.3141-50. ⟨10.1093/jxb/erv120⟩
Journal articles hal-01180477v1
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Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses

Mélanie Durand , Thomas Walter , Tiphène Pirnay , Thomas Naessens , Paul Guéguen et al.
Journal of Experimental Medicine, 2019, 216 (7), pp.1561-1581. ⟨10.1084/jem.20181994⟩
Journal articles hal-02440608v1
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Contribution of resident and circulating precursors to tumor-infiltrating CD8 + T cell populations in lung cancer

Paul Gueguen , Christina Metoikidou , Thomas Dupic , Myriam Lawand , Christel Goudot et al.
Science Immunology, 2021, 6 (55), ⟨10.1126/sciimmunol.abd5778⟩
Journal articles hal-03367764v1
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Kronos scRT: a uniform framework for single-cell replication timing analysis

Stefano Gnan , Joseph M Josephides , Xia Wu , Manuela Spagnuolo , Dalila Saulebekova et al.
Nature Communications, 2022, 13 (1), pp.2329. ⟨10.1038/s41467-022-30043-x⟩
Journal articles hal-03840947v1
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Kronos scRT: a uniform framework for single-cell replication timing analysis

Stefano Gnan , Joseph M Josephides , Xia Wu , Manuela Spagnuolo , Dalila Saulebekova et al.
2021
Preprints, Working Papers, ... hal-03436209v1
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Enrichment of centromeric DNA from human cells

Riccardo Gamba , Giulia Mazzucco , Therese Wilhelm , Leonid Velikovsky , Catalina Salinas-Luypaert et al.
PLoS Genetics, 2022, 18, ⟨10.1371/journal.pgen.1010306⟩
Journal articles hal-03874734v1

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

Amaury Leruste , Jimena Tosello , Rodrigo Nalio Ramos , Arnault Tauziède-Espariat , Solène Brohard et al.
Journal articles hal-02355172v1
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Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins

Mathilde Romagnoli , Stéphanie Cagnet , Aurélie Chiche , Laura Bresson , Sylvain Baulande et al.
Current Stem Cell Reports, In press, ⟨10.1016/j.stemcr.2019.02.008⟩
Journal articles hal-02082606v1
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Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure

Marie-Thérèse El-Daher , Nicolas Cagnard , Marine Gil , Marie Chansel da Cruz , Claire Leveau et al.
Cell Discovery, 2018, 4 (1), ⟨10.1038/s41421-018-0061-y⟩
Journal articles hal-01922535v1
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A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary

Rafael Galupa , Elphege Pierre Nora , Rebecca Worsley-Hunt , Christel Picard , Chris Gard et al.
Molecular Cell, 2020, 77 (2), pp.352-367.e8. ⟨10.1016/j.molcel.2019.10.030⟩
Journal articles hal-02884391v1