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Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy

Anne Montfort , Florie Bertrand , Julia Rochotte , Julia Gilhodes , Thomas Filleron et al.
Cancer Immunology Research, 2021, 9 (5), pp.568-582. ⟨10.1158/2326-6066.CIR-20-0342⟩
Journal articles inserm-03402255v1
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PPARγ is a tumor suppressor in basal bladder tumors offering new potential therapeutic opportunities

Laure Coutos-Thévenot , Syrine Beji , Hélène Neyret-Kahn , Quentin Pippo , Jacqueline Fontugne et al.
Preprints, Working Papers, ... hal-03424976v1
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Precise Alkoxyamine Design to Enable Automated Tandem Mass Spectrometry Sequencing of Digital Poly(phosphodiester)s

Kévin Launay , Jean‐arthur Amalian , Eline Laurent , Laurence Oswald , Abdelaziz Al Ouahabi et al.
Angewandte Chemie International Edition, 2021, 60 (2), pp.917-926. ⟨10.1002/anie.202010171⟩
Journal articles hal-03090783v1

Cleavable Binary Dyads: Simplifying Data Extraction and Increasing Storage Density in Digital Polymers

Gianni Cavallo , Salomé Poyer , Jean-Arthur Amalian , Florent Dufour , Alexandre Burel et al.
Angewandte Chemie International Edition, 2018, 57 (21), pp.6266--6269. ⟨10.1002/anie.201803027⟩
Journal articles hal-02091907v1

Epigenomic mapping identifies a super-enhancer repertoire that regulates cell identity in bladder cancers through distinct transcription factor networks

Hélène Neyret-Kahn , Jacqueline Fontugne , Xiang Yu Meng , Clarice Groeneveld , Luc Cabel et al.
Preprints, Working Papers, ... hal-03854062v1
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A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

Jing Liu , Daniela Ottaviani , Meriem Sefta , Céline Desbrousses , Elodie Chapeaublanc et al.
Nature Communications, 2021, 12 (1), pp.1-20. ⟨10.1038/s41467-021-25792-0⟩
Journal articles hal-03374490v1

Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility

Valérie Edmond , Florent Dufour , Guillaume Poiroux , Kenji Shoji , Marine Malleter et al.
Oncogene, 2015, 34 (8), pp.996-1005. ⟨10.1038/onc.2014.55⟩
Journal articles hal-01063558v1
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N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

Florent Dufour , Thibault Rattier , Sarah Shirley , Gaelle Picarda , Andrei Alexandru Constantinescu et al.
Cell Death and Differentiation, 2017, [Epub ahead of print]. ⟨10.1038/cdd.2016.150⟩
Journal articles inserm-01467849v1

Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors

Tom Baladi , Jessy Aziz , Florent Dufour , Valentina Abet , Véronique Stoven et al.
Bioorganic and Medicinal Chemistry, 2018, 26 (20), pp.5510-5530. ⟨10.1016/j.bmc.2018.09.031⟩
Journal articles hal-01986358v1
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TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer

Florent Dufour , Linda Silina , Hélène Neyret-Kahn , Aura Moreno-Vega , Clémentine Krucker et al.
British Journal of Cancer, 2019, 120 (5), pp.555-564. ⟨10.1038/s41416-019-0397-6⟩
Journal articles hal-02340153v1
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Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes

Neila Chekkat , Caterina Lombardo , Cendrine Seguin , Marie-Charlotte Lechner , Florent Dufour et al.
Oncotarget, 2018, 9 (21), pp.15566-15578. ⟨10.18632/oncotarget.24526⟩
Journal articles inserm-01717537v1
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Multifunctional polymeric implant coatings based on gelatin, hyaluronic acid derivative and chain length-controlled poly(arginine)

Helena Knopf-Marques , Julien Barthes , Sarah Lachaal , Angela Mutschler , Céline Muller et al.
Materials Science and Engineering: C, 2019, 104, pp.109898. ⟨10.1016/j.msec.2019.109898⟩
Journal articles hal-02524177v1
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TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

Florent Dufour , Thibault Rattier , Andrei Alexandru Constantinescu , Luciana Zischler , Aymeric Morlé et al.
Oncotarget, 2017, 8 (6), pp.9974-9985. ⟨10.18632/oncotarget.14285⟩
Journal articles inserm-01423110v1
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High-Capacity Digital Polymers: Storing Images in Single Molecules

Eline Laurent , Jean-Arthur Amalian , Marie Parmentier , Laurence Oswald , Abdelaziz Al Ouahabi et al.
Macromolecules, 2020, 53 (10), pp.4022-4029. ⟨10.1021/acs.macromol.0c00666⟩
Journal articles hal-02862054v1
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Recurrent activating mutations of PPARγ associated with luminal bladder tumors

Natacha Rochel , Clémentine Krucker , Laure Coutos-Thévenot , Judit Osz , Ruiyun Zhang et al.
Nature Communications, 2019, 10, pp.253. ⟨10.1038/s41467-018-08157-y⟩
Journal articles hal-01987515v1
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An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers

Mélanie Mahé , Florent Dufour , Hélène Neyret-Kahn , Aura Moreno-Vega , Claire Béraud et al.
EMBO Molecular Medicine, 2018, 10 (4), pp.e8163. ⟨10.15252/emmm.201708163⟩
Journal articles hal-02066552v1