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Resistance mechanisms to immune-checkpoint blockade in cancer: tumor-intrinsic and -extrinsic factors

Jonathan M. Pitt , Marie Vétizou , Romain Daillere , Maria Paula Roberti , Takahiro Yamazaki et al.
Immunity, 2016, 44 (6), pp.1255-1269. ⟨10.1016/j.immuni.2016.06.001⟩
Journal articles hal-02639871v1

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade

Nicolas Jacquelot , Takahiro Yamazaki , Maria Roberti , Connie Duong , Miles Andrews et al.
Cell Research, 2019, 29 (10), pp.846-861. ⟨10.1038/s41422-019-0224-x⟩
Journal articles hal-02461559v1

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Bertrand Routy , Emmanuelle Le Chatelier , Lisa Derosa , Connie Duong , Maryam Tidjani Alou et al.
Science, 2018, 359 (6371), pp.91-97. ⟨10.1126/science.aan3706⟩
Journal articles hal-02126484v1

Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors

Romain Daillère , Bertrand Routy , Anne-Gaëlle Goubet , Alexandria Cogdill , Gladys Ferrere et al.
OncoImmunology, 2020, 9 (1), ⟨10.1080/2162402x.2020.1794423⟩
Journal articles hal-03681841v1
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Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma

Nicolas Jacquelot , David P. Enot , Caroline Flament , Nadège Vimond , Carolin Blattner et al.
Journal of Clinical Investigation, 2016, 126 (3), pp.921-937. ⟨10.1172/JCI80071⟩
Journal articles hal-01295136v1
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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

Miles Andrews , Connie Duong , Vancheswaran Gopalakrishnan , Valerio Iebba , Wei-Shen Chen et al.
Nature Medicine, 2021, 27 (8), pp.1432-1441. ⟨10.1038/s41591-021-01406-6⟩
Journal articles hal-03333724v1
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Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients

Marion Picard , Satoru Yonekura , Karolina Slowicka , Ioanna Petta , Conrad Rauber et al.
Cell Death and Differentiation, 2021, 28 (5), pp.1532-1547. ⟨10.1038/s41418-020-00684-w⟩
Journal articles hal-03682003v1
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Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

Maria Paula Roberti , Satoru Yonekura , Connie P. M. Duong , Marion Picard , Gladys Ferrere et al.
Nature Medicine, 2020, 26 (6), p. 919-931. ⟨10.1038/s41591-020-0882-8⟩
Journal articles hal-03313676v1

Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors

Romain Daillère , Bertrand Routy , Anne-Gaëlle Goubet , Alexandria Cogdill , Gladys Ferrere et al.
OncoImmunology, 2020, 9 (1), ⟨10.1080/2162402x.2020.1794423⟩
Journal articles hal-03681591v1