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Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors

Romain Daillère , Bertrand Routy , Anne-Gaëlle Goubet , Alexandria Cogdill , Gladys Ferrere et al.
OncoImmunology, 2020, 9 (1), ⟨10.1080/2162402x.2020.1794423⟩
Journal articles hal-03681841v1

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Bertrand Routy , Emmanuelle Le Chatelier , Lisa Derosa , Connie Duong , Maryam Tidjani Alou et al.
Science, 2018, 359 (6371), pp.91-97. ⟨10.1126/science.aan3706⟩
Journal articles hal-02126484v1
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Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

Gladys Ferrere , Maryam Tidjani Alou , Peng Liu , Anne-Gaëlle Goubet , Marine Fidelle et al.
JCI Insight, 2021, 6 (2), ⟨10.1172/jci⟩
Journal articles hal-03169306v1

Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis

Satoru Yonekura , Safae Terrisse , Carolina Alves Costa Silva , Antoine Lafarge , Valerio Iebba et al.
Cancer Discovery, 2022, 12 (4), pp.1128-1151. ⟨10.1158/2159-8290.CD-21-0999⟩
Journal articles hal-03805638v1

Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients

Lisa Derosa , Bertrand Routy , Marine Fidelle , V.Alerio Iebba , Laurie Alla et al.
European Urology, 2020, 78, pp.195-206. ⟨10.1016/j.eururo.2020.04.044⟩
Journal articles hal-02569488v1

The immuno-oncological challenge of COVID-19

Lisa Derosa , Clea Melenotte , Franck Griscelli , Bertrand Gachot , Aurelien Marabelle et al.
NATURE CANCER, 2020, 1 (10), pp.946-964. ⟨10.1038/s43018-020-00122-3⟩
Journal articles hal-03149699v1

The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals

Jean-Eudes Fahrner , Imran Lahmar , Anne-Gaëlle Goubet , Yacine Haddad , Agathe Carrier et al.
Cancer Discovery, 2022, 12 (4), pp.958-983. ⟨10.1158/2159-8290.CD-21-1441⟩
Journal articles hal-03678977v1
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Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis

Anne-Gaëlle Goubet , Agathe Dubuisson , Arthur Geraud , François-Xavier Danlos , Safae Terrisse et al.
Cell Death and Differentiation, 2021, ⟨10.1038/s41418-021-00817-9⟩
Journal articles hal-03333920v1
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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

Miles Andrews , Connie Duong , Vancheswaran Gopalakrishnan , Valerio Iebba , Wei-Shen Chen et al.
Nature Medicine, 2021, 27 (8), pp.1432-1441. ⟨10.1038/s41591-021-01406-6⟩
Journal articles hal-03333724v1

Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis

Satoru Yonekura , Safae Terrisse , Carolina Alves Costa Silva , Antoine Lafarge , Valerio Iebba et al.
Cancer Discovery, 2022, 12 (4), pp.1128-1151. ⟨10.1158/2159-8290.CD-21-0999⟩
Journal articles hal-03642500v1

Escherichia coli –Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer

Anne-Gaëlle Goubet , Leonardo Lordello , Carolina Alves Costa Silva , Isabelle Peguillet , Marianne Gazzano et al.
Cancer Discovery, 2022, 12 (10), pp.2280-2307. ⟨10.1158/2159-8290.CD-22-0201⟩
Journal articles hal-03951702v1
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Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage

Aurélie Fluckiger , Romain Daillere , Mohamed Sassi , Barbara S Sixt , Peng Liu et al.
Science, 2020, 369 (6506), pp.936-942. ⟨10.1126/science.aax0701⟩
Journal articles inserm-02923397v1

COVID-19: a challenge for oncology services

Bertrand Routy , Lisa Derosa , Laurence Zitvogel , Guido Kroemer
OncoImmunology, 2020, 9 (1), ⟨10.1080/2162402X.2020.1760686⟩
Journal articles hal-03150177v1
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Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19

Aymeric Silvin , Nicolas Chapuis , Garett Dunsmore , Anne-Gaëlle Goubet , Agathe Dubuisson et al.
Cell, 2020, 182, pp.1401 - 1418.e18. ⟨10.1016/j.cell.2020.08.002⟩
Journal articles hal-03491454v1
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Immune responses during COVID-19 infection

Cléa Melenotte , Aymeric Silvin , Anne-Gaëlle Goubet , Imran Lahmar , Agathe Dubuisson et al.
OncoImmunology, 2020, 9 (1), pp.1807836. ⟨10.1080/2162402X.2020.1807836⟩
Journal articles hal-02940716v1
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Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

Maria Paula Roberti , Satoru Yonekura , Connie P. M. Duong , Marion Picard , Gladys Ferrere et al.
Nature Medicine, 2020, 26 (6), p. 919-931. ⟨10.1038/s41591-020-0882-8⟩
Journal articles hal-03313676v1

Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors

Romain Daillère , Bertrand Routy , Anne-Gaëlle Goubet , Alexandria Cogdill , Gladys Ferrere et al.
OncoImmunology, 2020, 9 (1), ⟨10.1080/2162402x.2020.1794423⟩
Journal articles hal-03681591v1
Image document

Immunodynamics of explanted human tumors for immuno-oncology

Agathe Dubuisson , Jean Eudes Fahrner , Anne Gaëlle Goubet , Safae A. Terrisse , Nicolas Voisin et al.
EMBO Molecular Medicine, 2021, 13 (1), ⟨10.15252/emmm.202012850⟩
Journal articles hal-03127487v1

Multifaceted modes of action of the anticancer probiotic Enterococcus hirae

Anne-Gaëlle Goubet , Richard Wheeler , Aurélie Fluckiger , Bo Qu , Fabien Lemaître et al.
Cell Death and Differentiation, 2021, 28 (7), pp.2276-2295. ⟨10.1038/s41418-021-00753-8⟩
Journal articles hal-03280464v1