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authIdHal_s : alexis-bemelmans

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors.

Uwe Maskos , B. E. Molles , S. Pons , M. Besson , B.P. Guiard et al.
Nature, 2005, 436 (7047), pp.103-7. ⟨10.1038/nature03694⟩
Journal articles istex pasteur-00162546v1

Loss of otx2 in the adult retina disrupts retinal pigment epithelium function, causing photoreceptor degeneration.

Michael Housset , Alexander Samuel , Mohamed Ettaiche , Alexis-Pierre Bemelmans , Francis Béby et al.
Journal of Neuroscience, 2013, 33 (24), pp.9890-904. ⟨10.1523/JNEUROSCI.1099-13.2013⟩
Journal articles hal-00843349v1
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The intellectual disability protein Oligophrenin1 controls astrocyte morphology and migration

Laure-Elise Pillet , Noémie Cresto , Yoann Saillour , Grégory Ghézali , Alexis-Pierre Bemelmans et al.
Glia, 2020, Epub ahead of print. ⟨10.1002/glia.23801⟩
Journal articles inserm-02506646v1

Fast calcium transients in dendritic spines driven by extreme statistics

Kanishka Basnayake , David Mazaud , Alexis Bemelmans , Nathalie Rouach , Eduard Korkotian et al.
PLoS Biology, 2019, 17 (6), pp.e2006202. ⟨10.1371/journal.pbio.2006202⟩
Journal articles hal-02626523v1

Insulin growth factor-1 protects against excitotoxicity in the rat striatum

Carole Escartin , Frédéric Boyer , Alexis-Pierre Bemelmans , Philippe Hantraye , Emmanuel Brouillet et al.
NeuroReport, 2004, 15 (14), pp.2251-2254. ⟨10.1097/00001756-200410050-00022⟩
Journal articles cea-02290615v1
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A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina

Alexis-Pierre Bemelmans , Sandra Duqué , Christel Rivière , Stéphanie Astord , Mélissa Desrosiers et al.
PLoS ONE, 2013, 8 (4), pp.e61618. ⟨10.1371/journal.pone.0061618⟩
Journal articles hal-01537691v1
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Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8

Hanen Khabou , Mélissa Desrosiers , Céline Winckler , Stéphane Fouquet , Gwenaëlle Auregan et al.
Biotechnology and Bioengineering, 2016, 113 (12), pp.2712-2724 ⟨10.1002/bit.26031⟩
Journal articles hal-01346351v1
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The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo

Noémie Cresto , Marie-Claude Gaillard , Camille Gardier , Francesco Gubinelli , Elsa Diguet et al.
Neurobiology of Disease, 2020, 134, pp.104614. ⟨10.1016/j.nbd.2019.104614⟩
Journal articles hal-03043360v1

Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease.

Mara Brizard , Carole Carcenac , Alexis-Pierre Bemelmans , Claude Feuerstein , Jacques Mallet et al.
Neurobiology of Disease, 2006, 21 (1), pp.90-101. ⟨10.1016/j.nbd.2005.06.015⟩
Journal articles istex hal-00166668v1
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Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning

Noémie Mazaré , Marc Oudart , Julien Moulard , Giselle Cheung , Romain Tortuyaux et al.
Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108076⟩
Journal articles hal-03013688v1
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rAAV-mediated cochlear gene therapy: Prospects and challenges for clinical application

Fabian Blanc , Michel Mondain , Alexis-Pierre Bemelmans , Corentin Affortit , Jean-Luc Puel et al.
Journal of Clinical Medicine, 2020, 9 (2), pp.589. ⟨10.3390/jcm9020589⟩
Journal articles hal-03521743v1
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A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina

Antoine Chaffiol , Romain P Caplette , Céline Jaillard , Elena Brazhnikova , Mélissa Desrosiers et al.
Molecular Therapy, 2017, 25 (11), pp.2546-2560. ⟨10.1016/j.ymthe.2017.07.011⟩
Journal articles hal-01844782v1

βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease

Mickael Audrain , Benoit Souchet , Sandro Alves , Romain Fol , Arthur Viodé et al.
Cerebral Cortex, 2018, 28 (11), pp.3976-3993. ⟨10.1093/cercor/bhx260⟩
Journal articles hal-02324980v1

Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines

Kanishka Basnayake , David Mazaud , Lilia Kushnireva , Alexis Bemelmans , Nathalie Rouach et al.
Science Advances , 2021, 7 (38), ⟨10.1126/sciadv.abh1376⟩
Journal articles hal-03516891v1
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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Laurie Galvan , Laetitia Francelle , Marie-Claude Gaillard , Lucie de Longprez , Maria-Angeles Carrillo-de Sauvage et al.
Brain - A Journal of Neurology , 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Journal articles hal-02074093v1
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TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons

Layal Maatouk , Anne-Claire Compagnion , Maria-Angeles Carrillo-De Sauvage , Alexis-Pierre Bemelmans , Sabrina Leclere-Turbant et al.
Nature Communications, 2018, 9, pp.2450. ⟨10.1038/s41467-018-04569-y⟩
Journal articles cea-01881325v1

Characterization of the striatal kinase Dclk3 and its neuroprotective effects against mutant huntingtin

E. Brouillet , L. Francelle , Laurie Galvan , M.-C Gaillard , M.-A Carrillo-de Sauvage et al.
SFN 2015, Oct 2015, CHICAGO, United States
Conference papers hal-02534708v1

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Laurie Galvan , Laetitia Francelle , Marie-Claude Gaillard , Lucie de Longprez , Maria-Angeles Carrillo-de Sauvage et al.
Brain - A Journal of Neurology , 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Journal articles hal-03060272v1
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IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats

Carole Escartin , Frédéric Boyer , Alexis-Pierre Bemelmans , Philippe Hantraye , Emmanuel Brouillet et al.
Neuroscience Letters, 2007, 425 (3), pp.167-172. ⟨10.1016/j.neulet.2007.08.031⟩
Journal articles cea-02290618v1
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Thérapie génique du système nerveux central: Considérations générales sur les vecteurs viraux pour le transfert de gène dans le cerveau

Ché Serguera , Alexis-Pierre Bemelmans
Revue Neurologique, 2014, 170 (12), pp.727-738. ⟨10.1016/j.neurol.2014.09.004⟩
Journal articles cea-03650651v1
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Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer’s Disease

Juliette Le Douce , Marianne Maugard , Julien Veran , Marco Matos , Pierrick Jégo et al.
Cell Metabolism, 2020, 31 (3), pp.503-517.e8. ⟨10.1016/j.cmet.2020.02.004⟩
Journal articles hal-02989009v2
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Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat

Marie D’orange , Gwenaëlle Auregan , Dimitri Cheramy , Mylène Gaudin-Guérif , Sarah Lieger et al.
Brain - A Journal of Neurology , 2018, 141 (2), pp.535-549. ⟨10.1093/brain/awx342⟩
Journal articles cea-02074052v1
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Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Kelly Ceyzériat , Lucile Ben Haim , Audrey Denizot , Dylan Pommier , Marco Matos et al.
Acta Neuropathologica Communications, 2018, 6 (1), pp.1047. ⟨10.1186/s40478-018-0606-1⟩
Journal articles hal-02074082v1

Chromatic serial multiphoton microscopy for multicolor imaging of large brain volumes

Lamiae Abdeladim , Katherine S. Matho , Solène Clavreul , Pierre Mahou , Jean-Marc Sintes et al.
Advances in Microscopic Imaging, Jun 2019, Munich, Germany. pp.7, ⟨10.1117/12.2526947⟩
Conference papers hal-02372159v1
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Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease

Océane Guillemaud , Kelly Ceyzériat , Thomas Saint-Georges , Karine Cambon , Fanny Petit et al.
2019
Preprints, Working Papers, ... cea-02392438v1

The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo

Noémie Cresto , Camille Gardier , Marie-Claude Gaillard , Francesco Gubinelli , Pauline Roost et al.
International Journal of Molecular Sciences, 2021, 22 (13), pp.6760. ⟨10.3390/ijms22136760⟩
Journal articles hal-03452142v1

mRNA trans -splicing in gene therapy for genetic diseases

Adeline Berger , Séverine Maire , Marie-Claude Gaillard , José-Alain Sahel , Philippe Hantraye et al.
Wiley Interdisciplinary Reviews: RNA, 2016, 7 (4), pp.487-498. ⟨10.1002/wrna.1347⟩
Journal articles cea-02073831v1
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Spectral-domain optical coherence tomography of the rodent eye: highlighting layers of the outer retina using signal averaging and comparison with histology.

Adeline Berger , Sophie Cavallero , Elisa Dominguez , Peggy Barbe , Manuel Simonutti et al.
PLoS ONE, 2014, 9 (5), pp.e96494. ⟨10.1371/journal.pone.0096494⟩
Journal articles hal-00990132v1

Repair of Rhodopsin mRNA by Spliceosome-Mediated RNA Trans -Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa

Adeline Berger , Stéphanie Lorain , Charlène Joséphine , Mélissa Desrosiers , Cécile Peccate et al.
Molecular Therapy, 2015, 23 (5), pp.918-930. ⟨10.1038/mt.2015.11⟩
Journal articles cea-02155559v1
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Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression.

Mickael Audrain , Romain Fol , Patrick Dutar , Brigitte Potier , Jean-Marie Billard et al.
Molecular Neurodegeneration, 2016, 11 (1), pp.5. ⟨10.1186/s13024-016-0070-y⟩
Journal articles inserm-01322473v1