Search - Archive ouverte HAL Access content directly

Filter your results

47 Results
authIdHal_s : christophe-guilhot

Biosynthesis and Roles of Phenolic Glycolipids and Related Molecules in Mycobacterium tuberculosis

Christophe Guilhot , Christian Chalut , Mamadou Daffé
The Mycobacterial Cell Envelope, ASM Press, pp.271-289, 2014, ⟨10.1128/9781555815783.ch17⟩
Book sections hal-03199103v1
Image document

Protein O-mannosylation deficiency increases LprG-associated lipoarabinomannan release by Mycobacterium tuberculosis and enhances the TLR2-associated inflammatory response

Henar Alonso , Julien Parra , Wladimir Malaga , Delphine Payros , Chia-Fang Liu et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-08489-7⟩
Journal articles hal-02323721v1

Mycobacterium leprae pgl1 expression by BCG increases CR3 mediated entry into mouse myeloid cells and induces Syk/NFAT cytokine production

Emilie Doz-Deblauwe , Florence Carreras , Aude Remot , Mathieu Epardaud , Caroline Demangel et al.
Journées d'Animation Scientifique du Département Santé Animale, Oct 2018, Nantes, France. , 2018, Santé Animale et Santé Publique
Conference poster hal-02736584v1
Image document

Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages

Reid Oldenburg , Véronique Mayau , Jacques Prandi , Ainhoa Arbues , Catherine Astarie-Dequeker et al.
Frontiers in Immunology, 2018, 9, 12 p. ⟨10.3389/fimmu.2018.00002⟩
Journal articles hal-02323696v1
Image document

Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

Catherine Astarie-Dequeker , Laurent Le Guyader , Wladimir Malaga , Fam-Ky Seaphanh , Christian Chalut et al.
PLoS Pathogens, 2009, 5 (2), pp.e1000289. ⟨10.1371/journal.ppat.1000289⟩
Journal articles hal-02333313v1

Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis

Florence Levillain , Hongmin Kim , Kee Woong Kwon , Simon Clark , Felipe Cia et al.
Vaccine, 2020, 38 (6), pp.1416-1423. ⟨10.1016/j.vaccine.2019.11.085⟩
Journal articles hal-03014488v1
Image document

The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Aïcha Bah , Merlin Sanicas , Jérôme Nigou , Christophe Guilhot , Catherine Astarie-Dequeker et al.
Cells, 2020, 9 (3), pp.666. ⟨10.3390/cells9030666⟩
Journal articles hal-02650295v1
Image document

Mycobacterium tuberculosis and M. bovis BCG Moreau Fumarate Reductase Operons Produce Different Polypeptides That May Be Related to Non-canonical Functions

Marcos Gustavo Araujo Schwarz , Deborah Antunes , Paloma Rezende Corrêa , Antônio José Da Silva-Gonçalves , Wladimir Malaga et al.
Frontiers in Microbiology, 2021, 11, pp.624121. ⟨10.3389/fmicb.2020.624121⟩
Journal articles hal-03109443v1
Image document

Functional Characterisation of Three O-methyltransferases Involved in the Biosynthesis of Phenolglycolipids in Mycobacterium tuberculosis

Roxane Simeone , Gaëlle Huet , Patricia Constant , Wladimir Malaga , Anne Lemassu et al.
PLoS ONE, 2013, 8 (3), pp.e58954. ⟨10.1371/journal.pone.0058954⟩
Journal articles hal-02391855v1
Image document

Conformational flexibility of coenzyme A and its impact on the post‐translational modification of acyl carrier proteins by 4′‐phosphopantetheinyl transferases

Minh Chau Nguyen , Olivier Saurel , Coralie Carivenc , Sabine Gavalda , Stéphane Saitta et al.
FEBS Journal, 2020, 287, pp.4729 - 4746. ⟨10.1111/febs.15273⟩
Journal articles hal-02950584v1
Image document

Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli

Aideen C Allen , Wladimir Malaga , Cyril Gaudin , Arnaud Volle , Flavie Moreau et al.
Nature Microbiology, 2021, 6 (8), pp.1082-1093. ⟨10.1038/s41564-021-00938-4⟩
Journal articles hal-03318178v1
Image document

Pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

Eva C. Boritsch , Wafa Frigui , Alessandro Cascioferro , Wladimir Malaga , Gilles Etienne et al.
Nature Microbiology, 2016, 1 (février 2016), ⟨10.1038/nmicrobiol.2015.19⟩
Journal articles pasteur-01265519v1

Identification of a stress-induced factor of Corynebacterineae that is involved in the regulation of the outer membrane lipid composition.

Xavier Meniche , Cécile Labarre , Célia de Sousa-d'Auria , Emilie Huc , Françoise Laval et al.
Journal of Bacteriology, 2009, 191 (23), pp.7323-32. ⟨10.1128/JB.01042-09⟩
Journal articles hal-00529742v1

Efficient method for targeted gene disruption by homologous recombination in Mycobacterium avium subspecie paratuberculosis

Maria Natalia Alonso , Wladimir Malaga , Michael Mc Neil , Mary Jackson , Maria Isabel Romano et al.
Research in Microbiology, 2020, 171 (5-6), pp.203-210. ⟨10.1016/j.resmic.2020.04.001⟩
Journal articles hal-03014452v1

Mycobacterium bovis BCG moreau is naturally deficient in homologous recombination

Marcos Gustavo Araujo Schwarz , Paloma Rezende Corrêa , Wladimir Malaga , Christophe Guilhot , Leila Mendonça-Lima et al.
Tuberculosis, 2020, 123, pp.101956. ⟨10.1016/⟩
Journal articles hal-03014446v1
Image document

Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds

Coralie Carivenc , Laurent Maveyraud , Claire Blanger , Stéphanie Ballereau , Coralie Roy-Camille et al.
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-97197-4⟩
Journal articles hal-03345048v1
Image document

Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes

Guillaume Tabouret , Catherine Astarie-Dequeker , Caroline Demangel , Wladimir Malaga , Patricia Constant et al.
PLoS Pathogens, 2010, 6 (10), pp.e1001159. ⟨10.1371/journal.ppat.1001159⟩
Journal articles pasteur-01376090v1

The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages

Jacques Augenstreich , Evert Haanappel , Guillaume Ferré , Georges Czaplicki , Franck Jolibois et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019
Journal articles hal-02378775v1

Mycobacterium leprae PG-1 production by BCG favors CR3 mediated entry into mouse myeloid cells and incrases SYK-controlled cytokine production

Emilie Doz , Florence Carreras , Christophe Guilhot , Nathalie Winter
Journées d'Animation Scientifique du Département Santé Animale, Oct 2013, Cap d'Agde, France. 2013, Santé animale et santé publique
Conference poster hal-02744728v1
Image document

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Thomas Laval , Laura Pedró-Cos , Wladimir Malaga , Laure Guenin-Macé , Alexandre Pawlik et al.
eLife, 2021, 10, pp.e71946. ⟨10.7554/eLife.71946⟩
Journal articles pasteur-03534651v1

Trehalose Polyphleates Are Produced by a Glycolipid Biosynthetic Pathway Conserved across Phylogenetically Distant Mycobacteria

Sophie Burbaud , Françoise Laval , Anne Lemassu , Mamadou Daffé , Christophe Guilhot et al.
Cell Chemical Biology, 2016, 23 (2), pp.278-289. ⟨10.1016/j.chembiol.2015.11.013⟩
Journal articles hal-02322348v1

Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis

Roxane Simeone , Mathieu Léger , Patricia Constant , Wladimir Malaga , Hedia Marrakchi et al.
FEBS Journal, 2010, 277 (12), pp.2715-2725. ⟨10.1111/j.1742-464X.2010.07688.x⟩
Journal articles pasteur-02862996v1

ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis

Jacques Augenstreich , Ainhoa Arbues , Roxane Simeone , Evert Haanappel , Alice Wegener et al.
Cellular Microbiology, 2017, 19 (7), pp.e12726. ⟨10.1111/cmi.12726⟩
Journal articles hal-02326055v1

Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

J. Gonzalo-Asensio , W. Malaga , Alexandre Pawlik , Catherine Astarie-Dequeker , C. Passemar et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (31), pp.11491-11496. ⟨10.1073/pnas.1406693111⟩
Journal articles hal-02325922v1
Image document

Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases

Anna D Grabowska , Yoann Brison , Laurent Maveyraud , Sabine Gavalda , Alexandre Faille et al.
ACS Chemical Biology, 2020, 15 (12), pp.3206 - 3216. ⟨10.1021/acschembio.0c00772⟩
Journal articles hal-03752170v1
Image document

Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages

Delphine Payros , Henar Alonso , Wladimir Malaga , Arnaud Volle , Serge Mazères et al.
PLoS Pathogens, 2021, 17 (11), pp.e1010020. ⟨10.1371/journal.ppat.1010020⟩
Journal articles hal-03420756v1

Mycobacterium leprae PGL-1 expression by BCG increases CR3 mediated entry into mouse myeloid cells and triggers the Syk/NFAT pathway to induce a specific cytokine program

Emilie Doz-Deblauwe , Florence Carreras , Aude Remot , Ainhoa Arbues , Mathieu Epardaud et al.
5. conférence Mycoclub, Société Française de Microbiologie (SFM). FRA., May 2017, Montigny le Bretonneux, France
Conference papers hal-02733847v1
Image document

Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13

Fabien Bergeret , Sabine Gavalda , Christian Chalut , Wladimir Malaga , Annaïk Quémard et al.
Journal of Biological Chemistry, 2012, 287, pp.33675 - 33690. ⟨10.1074/jbc.m111.325639⟩
Journal articles hal-03003064v1
Image document

Detection of soluble co-factor dependent protein expression in vivo : Application to the 4′-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis

Karine Rottier , Alexandre Faille , Thomas Prudhomme , Cécile Leblanc , Christian Chalut et al.
Journal of Structural Biology, 2013, 183 (3), pp.320 - 328. ⟨10.1016/j.jsb.2013.07.010⟩
Journal articles hal-03002994v1

Bovine tubercle bacilli: evolution associated with loss of transmission capacity in humans

Roland Brosch , Christophe Guilhot
médecine/sciences, 2015, 31 (2), pp.123-126. ⟨10.1051/medsci/20153102003⟩
Journal articles hal-02325939v1