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authIdHal_s : jerome-nigou

Mycobacterial Lipomannan Induces Granuloma Macrophage Fusion via a TLR2-Dependent, ADAM9- and β 1 Integrin-Mediated Pathway

Marie-Pierre Puisségur , Guillaume Lay , Martine Gilleron , Laure Botella , Jérôme Nigou et al.
Journal of Immunology, 2007, 178 (5), pp.3161-3169. ⟨10.4049/jimmunol.178.5.3161⟩
Journal articles hal-03177922v1

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants

Anne-Laure Roux , Aurélie Ray , Alexandre Pawlik , Halima Medjahed , Gilles Etienne et al.
Cellular Microbiology, 2011, 13 (5), pp.692-704. ⟨10.1111/j.1462-5822.2010.01565.x⟩
Journal articles pasteur-02618829v1
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Scrutiny of Mycobacterium tuberculosis 19 kDa antigen proteoforms provides new insights in the lipoglycoprotein biogenesis paradigm

Julien Parra , Julien Marcoux , Isabelle Poncin , Stéphane Canaan , Jean Louis Herrmann et al.
Scientific Reports, 2017, 7, pp.43682. ⟨10.1038/srep43682⟩
Journal articles hal-01791689v1
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The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Aïcha Bah , Merlin Sanicas , Jérôme Nigou , Christophe Guilhot , Catherine Astarie-Dequeker et al.
Cells, 2020, 9 (3), pp.666. ⟨10.3390/cells9030666⟩
Journal articles hal-02650295v1
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Structural and functional analysis of the Francisella lysine decarboxylase as a key actor in oxidative stress resistance

Jan Felix , Claire Siebert , Juila Novion Ducassou , Jérôme Nigou , Pierre Simon Garcia et al.
Scientific Reports, 2021, 11 (1), pp.972. ⟨10.1038/s41598-020-79611-5⟩
Journal articles hal-03118173v1

Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response.

Jérôme Nigou , Martine Gilleron , Mauricio Rojas , Luis F García , Martin Thurnher et al.
Microbes and Infection, 2002, 4 (9), pp.945-53
Journal articles hal-00177974v1

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

Henrieta Škovierová , Gerald Larrouy-Maumus , Jian Zhang , Devinder Kaur , Nathalie Barilone et al.
Glycobiology, 2009, 19 (11), pp.1235-1247. ⟨10.1093/glycob/cwp116⟩
Journal articles hal-03177973v1
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Lipoglycans Contribute to Innate Immune Detection of Mycobacteria

Shyam Krishna , Aurélie Ray , Shiv Dubey , Gerald Larrouy-Maumus , Christian Chalut et al.
PLoS ONE, 2011, 6 (12), pp.e28476. ⟨10.1371/journal.pone.0028476⟩
Journal articles hal-02391864v1

Mannan Chain Length Controls Lipoglycans Signaling via and Binding to TLR2

Jérôme Nigou , Thierry Vasselon , Aurélie Ray , Patricia Constant , Martine Gilleron et al.
Journal of Immunology, 2008, 180 (10), pp.6696-6702. ⟨10.4049/jimmunol.180.10.6696⟩
Journal articles hal-03177926v1

A glycomic approach reveals a new mycobacterial polysaccharide

Gerald Larrouy-Maumus , Martine Gilleron , Henrieta Skovierová , Sophie Zuberogoitia , Patrick Brennan et al.
Glycobiology, 2015, 25 (11), pp.1163-1171. ⟨10.1093/glycob/cwv061⟩
Journal articles hal-03178008v1

Identification of a novel mannose-capped lipoarabinomannan from Amycolatopsis sulphurea

Kevin Gibson , Martine Gilleron , Patricia Constant , Germain Puzo , Jérôme Nigou et al.
Biochemical Journal, 2003, 372 (3), pp.821-829. ⟨10.1042/BJ20030197⟩
Journal articles hal-03177850v1

Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis

Shiva Kumar Angala , Michael Mcneil , Libin Shi , Maju Joe , Ha Pham et al.
ACS Chemical Biology, 2017, 12 (3), pp.682-691. ⟨10.1021/acschembio.6b01071⟩
Journal articles hal-03178068v1
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Rational design of adjuvants targeting the C-type lectin Mincle

Alexiane Decout , Sandro Silva-Gomes , Daniel Drocourt , Sophie Barbe , Isabelle André et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (10), pp.2675-2680. ⟨10.1073/pnas.1612421114⟩
Journal articles hal-01607936v1

Identification of an ?(1?6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosis

Arun Mishra , Luke Alderwick , Doris Rittmann , Raju Tatituri , Jérôme Nigou et al.
Molecular Microbiology, 2007, 65 (6), pp.1503-1517. ⟨10.1111/j.1365-2958.2007.05884.x⟩
Journal articles hal-03177909v1

Structural analysis of mycobacterial lipoglycans.

Jérôme Nigou , Martine Gilleron , Thérèse Brando , Germain Puzo
Applied Biochemistry and Biotechnology, 2004, 118 (1-3), pp.253-67
Journal articles hal-00177964v1

Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan.

Emilie Doz , Stéphanie Rose , Jérôme Nigou , Martine Gilleron , Germain Puzo et al.
Journal of Biological Chemistry, 2007, 282 (36), pp.26014-25. ⟨10.1074/jbc.M702690200⟩
Journal articles hal-00318491v1
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Disruption of the SucT acyltransferase in Mycobacterium smegmatis abrogates succinylation of cell envelope polysaccharides

Zuzana Palčeková , Shiva Angala , Juan Manuel Belardinelli , Haig Eskandarian , Maju Joe et al.
Journal of Biological Chemistry, 2019, 294 (26), pp.10325-10335. ⟨10.1074/jbc.RA119.008585⟩
Journal articles hal-02325319v1

Acylation Determines the Toll-like receptor (TLR)-dependent Positive Versus TLR2-, Mannose Receptor-, and SIGNR1-independent Negative Regulation of Pro-inflammatory Cytokines by Mycobacterial Lipomannan

Emilie Doz , Stéphanie Rose , Jérôme Nigou , Martine Gilleron , Germain Puzo et al.
Journal of Biological Chemistry, 2007, 282 (36), pp.26014-26025. ⟨10.1074/jbc.M702690200⟩
Journal articles hal-03177915v1

Lipoteichoic Acid in Streptomyces hygroscopicus: Structural Model and Immunomodulatory Activities

Marlène Cot , Aurélie Ray , Martine Gilleron , Alain Vercellone , Gerald Larrouy-Maumus et al.
PLoS ONE, 2011, 6 (10), pp.e26316. ⟨10.1371/journal.pone.0026316⟩
Journal articles hal-03177994v1

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

Landry Blanc , Martine Gilleron , Jacques Prandi , Ok-Ryul Song , Mi-Seon Jang et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (42), pp.11205-11210. ⟨10.1073/pnas.1707840114⟩
Journal articles hal-03178071v1

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity.

Sylvain Pitarque , Jean-Louis Herrmann , Jean-Luc Duteyrat , Mary Jackson , Graham R Stewart et al.
Biochemical Journal, 2005, 392 (Pt 3), pp.615-24. ⟨10.1042/BJ20050709⟩
Journal articles pasteur-01372648v1
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Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages

Delphine Payros , Henar Alonso , Wladimir Malaga , Arnaud Volle , Serge Mazères et al.
PLoS Pathogens, 2021, 17 (11), pp.e1010020. ⟨10.1371/journal.ppat.1010020⟩
Journal articles hal-03420756v1
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Potential Plasticity of the Mannoprotein Repertoire Associated to Mycobacterium tuberculosis Virulence Unveiled by Mass Spectrometry-Based Glycoproteomics

Laure Tonini , Bashir Sadet , Alexandre Stella , David Bouyssié , Jérôme Nigou et al.
Molecules, 2020, 25 (10), pp.2348. ⟨10.3390/molecules25102348⟩
Journal articles hal-03032960v1
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C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells

Anthony Troegeler , Ingrid Mercier , Céline Cougoule , Danilo Pietretti , André Colom et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (4), pp.E540-E549. ⟨10.1073/pnas.1613254114⟩
Journal articles hal-02348507v1
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Efficacy of bedaquiline, alone or in combination with imipenem, against Mycobacterium abscessusin C3HeB/FeJ mice

Vincent Le Moigne , Clément Raynaud , Flavie Moreau , Christian Dupont , Jérôme Nigou et al.
Antimicrobial Agents and Chemotherapy, 2020, 64 (6), ⟨10.1128/AAC.00114-20⟩
Journal articles hal-03032987v1
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Synthetic mycobacterial molecular patterns partially complete Freund’s adjuvant

Jean-Yves Dubé , Fiona Mcintosh , Juan G Zarruk , Samuel David , Jérôme Nigou et al.
Scientific Reports, 2020, 10 (1), pp.5874. ⟨10.1038/s41598-020-62543-5⟩
Journal articles hal-03031804v1
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Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

Marie Vétizou , Jonathan M. Pitt , Romain Daillere , Patricia P. Lepage , Nadine Waldschmitt et al.
Science, 2015, 350 (6264), pp.1079-1084. ⟨10.1126/science.aad1329⟩
Journal articles hal-02639698v1
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Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis

Anthony Troegeler , Geanncarlo Lugo-Villarino , Søren Hansen , Voahangy Rasolofo , Maiken Lumby Henriksen et al.
PLoS ONE, 2015, 10 (7), pp.e0132692. ⟨10.1371/journal.pone.0132692⟩
Journal articles hal-02348524v1

Lipid and Lipoarabinomannan Isolation and Characterization

Mamadou Daffé , Marie-Antoinette Lanéelle , Lucie Spina , Jérôme Nigou , Anne Lemassu et al.
Mycobacteria Protocols, 2314, Springer US, pp.109-150, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1460-0_4⟩
Book sections hal-03404287v1

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization

Philippe Barthe , Romain Veyron-Churlet , Angélique De visch , Martine Gilleron , Jean-Michel Saliou et al.
Structure, 2016, 24 (10), pp.1788-1794. ⟨10.1016/j.str.2016.07.009⟩
Journal articles hal-03178065v1