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authIdHal_s : laurent-kremer

Use of the \textitSalmonella MgtR peptide as an antagonist of the \textitMycobacterium MgtC virulence factor

Claudine Belon , Mariana Rosas Olvera , Eric Vives , Laurent Kremer , Laila Gannoun-Zaki et al.
Future Microbiology, 2016, 11 (2), pp.215--225. ⟨10.2217/fmb.15.134⟩
Journal articles hal-01878031v1
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Delineating the Physiological Roles of the PE and Catalytic Domains of LipY in Lipid Consumption in Mycobacterium-Infected Foamy Macrophages

Pierre Santucci , Sadia Diomandé , Isabelle Poncin , Laetitia Alibaud , Albertus Viljoen et al.
Infection and Immunity, 2018, 86 (9), ⟨10.1128/IAI.00394-18⟩
Journal articles hal-01860679v1
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Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis

Phuong Chi Nguyen , Vincent Delorme , Anaïs Benarouche , Benjamin Martin , Rishi Paudel et al.
Scientific Reports, 2017, 7, pp.11751. ⟨10.1038/s41598-017-11843-4⟩
Journal articles hal-01791688v1

Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT).

Hemza Ghadbane , Alistair K Brown , Laurent Kremer , Gurdyal S Besra , Klaus Fütterer et al.
Acta crystallographica Section F : Structural biology communications [2014-..], 2007, 63 (Pt 10), pp.831-5. ⟨10.1107/S1744309107042455⟩
Journal articles hal-00203080v1

Mycobacterial lipomannan induces matrix metalloproteinase-9 expression in human macrophagic cells through a Toll-like receptor 1 (TLR1)/TLR2- and CD14-dependent mechanism.

Elisabeth Elass , Laetitia Aubry , Maryse Masson , Denys Agnès , Yann Guérardel et al.
Infection and Immunity, 2005, 73, pp.7064-7068
Journal articles hal-00087033v1

Lipomannans, but not lipoarabinomannans, purified from Mycobacterium chelonae and Mycobacterium kansasii induce TNF-alpha and IL-8 secretion by a CD14-toll-like receptor 2-dependent mechanism.

Cecile Vignal , Yann Guerardel , Laurent Kremer , Maryse Masson , Dominique Legrand et al.
Journal of Immunology, 2003, 171 (4), pp.2014-23
Journal articles hal-00149429v1

MgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection

Vincent Le Moigne , Claudine Belon , Céline Goulard , Geoffrey Accard , Audrey Bernut et al.
Infection and Immunity, 2016, 84 (10), pp.2895-2903. ⟨10.1128/IAI.00359-16⟩
Journal articles hal-02283984v1

Molecular structure of EmbR, a response element of Ser/Thr kinase signaling in Mycobacterium tuberculosis

Luke Alderwick , Virginie Molle , Laurent Kremer , Alain Cozzone , Timothy Dafforn et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (8), pp.2558-2563. ⟨10.1073/pnas.0507766103⟩
Journal articles hal-02282917v1

Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism.

Philippe Barthe , Christian Roumestand , Marc J Canova , Laurent Kremer , Corinne Hurard et al.
Structure, 2009, 17 (4), pp.568-78. ⟨10.1016/j.str.2009.02.012⟩
Journal articles hal-00458845v1

Mycobacterium tuberculosis S-adenosyl-l-homocysteine hydrolase is negatively regulated by Ser/Thr phosphorylation

Rosa Milagros Corrales , Jade Leiba , Martin Cohen-Gonsaud , Virginie Molle , Laurent Kremer et al.
Biochemical and Biophysical Research Communications, 2013, 430 (2), pp.858-864. ⟨10.1016/j.bbrc.2012.11.038⟩
Journal articles hal-02282662v1

Structural analysis of an unusual bioactive N-acylated lipo-oligosaccharide LOS-IV in Mycobacterium marinum

Yoann Rombouts , Elisabeth Elass , Christophe Biot , Emmanuel Maes , Bernadette Coddeville et al.
Journal of the American Chemical Society, 2010, 132 (45), pp.16073-84. ⟨10.1021/ja105807s⟩
Journal articles hal-00641528v1
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The Mycobacterium tuberculosis Ser/Thr kinase substrate Rv2175c is a DNA-binding protein regulated by phosphorylation.

Martin Cohen-Gonsaud , Philippe Barthe , Marc J Canova , Charlotte Stagier-Simon , Laurent Kremer et al.
Journal of Biological Chemistry, 2009, 284 (29), pp.19290-19300. ⟨10.1074/jbc.M109.019653⟩
Journal articles hal-00458843v1
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Un nouvel espoir pour traiter les infections persistantes à Mycobacterium abscessus ?

Clément Raynaud , Laurent Kremer
médecine/sciences, 2020, 36 (8-9), pp.691-694. ⟨10.1051/medsci/2020138⟩
Journal articles hal-02919324v1
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Phosphorylation of the Mycobacterium tuberculosis β-Ketoacyl-Acyl Carrier Protein Reductase MabA Regulates Mycolic Acid Biosynthesis

Romain Veyron-Churlet , Isabelle Zanella-Cléon , Martin Cohen-Gonsaud , Virginie Molle , Laurent Kremer et al.
Journal of Biological Chemistry, 2010, 285 (17), pp.12714-12725. ⟨10.1074/jbc.M110.105189⟩
Journal articles hal-02282774v1
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Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?

Ivy Mallick , Pierre Santucci , Isabelle Poncin , Vanessa Point , Laurent Kremer et al.
FEMS Microbiology Reviews, 2021, ⟨10.1093/femsre/fuab029⟩
Journal articles hal-03255780v1
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Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus

Matt Johansen , Jean-Louis Herrmann , Laurent Kremer
Nature Reviews Microbiology, 2020, 18 (7), Online ahead of print. ⟨10.1038/s41579-020-0331-1⟩
Journal articles inserm-02494720v1

Synthesis and in vitro antitubercular activity of ferrocene-based hydrazones

A. Mahajan , Laurent Kremer , S. Louw , Yann Guerardel , Kelly Chibale et al.
Bioorganic and Medicinal Chemistry Letters, 2011, 21 (10), pp.2866-2868. ⟨10.1016/j.bmcl.2011.03.082⟩
Journal articles istex hal-00641742v1

Variedly connected 1,8-naphthalimide-7-chloroquinoline conjugates: Synthesis, anti-mycobacterial and cytotoxic evaluation

Shalini Shalini , Matt Johansen , Laurent Kremer , Vipan Kumar
Bioorganic Chemistry, 2019, 92, pp.103241. ⟨10.1016/j.bioorg.2019.103241⟩
Journal articles inserm-02480350v1
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Mycobacterium tuberculosis Lipolytic Enzymes as Potential Biomarkers for the Diagnosis of Active Tuberculosis

Belinda Brust , Mélanie Lecoufle , Edouard Tuaillon , Luc Dedieu , Stéphane Canaan et al.
PLoS ONE, 2011, 6 (9), pp.e25078. ⟨10.1371/journal.pone.0025078⟩
Journal articles hal-02649423v1
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Laurent Kremer
Biochimie [q-bio.BM]. Université Montpellier II - Sciences et Techniques du Languedoc, 2007
Habilitation à diriger des recherches tel-00259336v1

A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus

Christian Dupont , Albertus Viljoen , Faustine Dubar , Mickaël Blaise , Audrey Bernut et al.
Molecular Microbiology, 2016, 101 (3), pp.515-529. ⟨10.1111/mmi.13406⟩
Journal articles hal-02137602v1
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Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria

Pierre Santucci , Matt Johansen , Vanessa Point , Isabelle Poncin , Albertus Viljoen et al.
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-45164-5⟩
Journal articles hal-02276153v1
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B cells response directed against Cut4 and CFP21 lipolytic enzymes in active and latent tuberculosis infections

Wendy Rénier , Arnaud Bourdin , Pierre-Alain Rubbo , Marianne Peries , Luc Dedieu et al.
PLoS ONE, 2018, 13 (4), pp.e0196470. ⟨10.1371/journal.pone.0196470⟩
Journal articles hal-01783443v1

Protein PknE, a novel transmembrane eukaryotic-like serine/threonine kinase from Mycobacterium tuberculosis

Virginie Molle , Christine Girard-Blanc , Laurent Kremer , Patricia Doublet , Alain Cozzone et al.
Biochemical and Biophysical Research Communications, 2003, 308 (4), pp.820-825. ⟨10.1016/s0006-291x(03)01476-1⟩
Journal articles istex hal-02282931v1

An FHA Phosphoprotein Recognition Domain Mediates Protein EmbR Phosphorylation by PknH, a Ser/Thr Protein Kinase from Mycobacterium tuberculosis †

Virginie Molle , Laurent Kremer , Christine Girard-Blanc , Gurdyal Besra , Alain Cozzone et al.
Biochemistry, 2003, 42 (51), pp.15300-15309. ⟨10.1021/bi035150b⟩
Journal articles istex hal-02282926v1

Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY.

Kanhu C Mishra , Chantal de Chastellier , Yeddula Narayana , Pablo Bifani , Alistair K Brown et al.
Infection and Immunity, 2008, 76 (1), pp.127-40. ⟨10.1128/IAI.00410-07⟩
Journal articles hal-00202869v1

Mycobacterial lipomannan induces matrix metalloproteinase-9 expression in human macrophagic cells through a Toll-like receptor 1 (TLR1)/TLR2- and CD14-dependent mechanism.

Elisabeth Elass , Laeticia Aubry , Maryse Masson , Agnés Denys , Yann Guerardel et al.
Infection and Immunity, 2005, 73 (10), pp.7064-8. ⟨10.1128/IAI.73.10.7064-7068.2005⟩
Journal articles hal-00087166v1
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Overexpression of the KdpF Membrane Peptide in Mycobacterium bovis BCG Results in Reduced Intramacrophage Growth and Altered Cording Morphology

Laila Gannoun-Zaki , Laeticia Alibaud , Severine Carrere-Kremer , Laurent Kremer , Anne-Béatrice Blanc-Potard et al.
PLoS ONE, 2013, 8 (4), pp.e60379. ⟨10.1371/journal.pone.0060379⟩
Journal articles hal-02281764v1
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The Mycobacterium tuberculosis {beta}-Ketoacyl-Acyl Carrier Protein Synthase III Activity Is Inhibited by Phosphorylation on a Single Threonine Residue

Romain Veyron-Churlet , Virginie Molle , Rebecca C Taylor , Alistair K Brown , Gurdyal S Besra et al.
Journal of Biological Chemistry, 2009, 284 (10), pp.6414-6424. ⟨10.1074/jbc.M806537200⟩
Journal articles hal-00373656v1
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Structural analysis of the N ‐acetyltransferase Eis1 from Mycobacterium abscessus reveals the molecular determinants of its incapacity to modify aminoglycosides

Kien Lam Ung , Laurent Kremer , Mickael Blaise
Proteins - Structure, Function and Bioinformatics, 2020, 89, pp.94 - 106. ⟨10.1002/prot.25997⟩
Journal articles hal-02988304v2