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authIdHal_s : mauro-modesti
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Human RPA activates BLM’s bidirectional DNA unwinding from a nick

Zhenheng Qin , Lulu Bi , Xi-Miao Hou , Siqi Zhang , Xia Zhang et al.
Journal articles hal-03080992v1

Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining

Davide Normanno , Aurélie Négrel , Abinadabe J de Melo , Stéphane Betzi , Katheryn Meek et al.
Journal articles hal-01541119v1

Reconstitution of anaphase DNA bridge recognition and disjunction

Kata Sarlós , Andreas Biebricher , Anna Bizard , Julia Bakx , Anna Ferreté-Bonastre et al.
Nature Structural and Molecular Biology, 2018, 25 (9), pp.868-876. ⟨10.1038/s41594-018-0123-8⟩
Journal articles hal-02144105v1

The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition

Lulu Bi , Zhenheng Qin , Teng Wang , Yanan Li , Xinshuo Jia et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), ⟨10.1073/pnas.2116462119⟩
Journal articles hal-03874139v1
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ExoMeg1: a new exonuclease from metagenomic library

Rita C. B. Silva-Portela , F C Carvalho , Carolina P Pereira , Nadja P de Souza-Pinto , Mauro Modesti et al.
Scientific Reports, 2016, 6, pp.19712. ⟨10.1038/srep19712⟩
Journal articles hal-01456273v1

Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling

Mauro Modesti , Wei Ting C. Lee , Yandong Yin , Michael Morten , Peter Tonzi et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-22830-9⟩
Journal articles hal-03438622v1

A basal-level activity of ATR links replication fork surveillance and stress response

Yandong Yin , Wei Ting Chelsea Lee , Dipika Gupta , Huijun Xue , Peter Tonzi et al.
Molecular Cell, 2021, 81 (20), pp.4243-4257.e6. ⟨10.1016/j.molcel.2021.08.009⟩
Journal articles hal-03874134v1

Bloom Syndrome Helicase Compresses Single‐Stranded DNA into Phase‐Separated Condensates

Teng Wang , Jiaojiao Hu , Yanan Li , Lulu Bi , Lijuan Guo et al.
Angewandte Chemie International Edition, 2022, 61 (39), ⟨10.1002/anie.202209463⟩
Journal articles hal-03874143v1

Simultaneous Mechanical and Fluorescence Detection of Helicase-Catalyzed DNA Unwinding

Lulu Bi , Zhenheng Qin , Xi-Miao Hou , Mauro Modesti , Bo Sun et al.
Optical Tweezers, 2478, Springer US, pp.329-347, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2229-2_12⟩
Book sections inserm-03825784v1

Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex

Mauro Modesti , Rohit Prakash , Thomas Sandoval , Florian Morati , Jennifer Zagelbaum et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-24205-6⟩
Journal articles hal-03438617v1

Insights into the control of RAD51 nucleoprotein filament dynamics from single-molecule studies

Florian Morati , Mauro Modesti
Current Opinion in Genetics and Development, 2021, 71, pp.182-187. ⟨10.1016/j.gde.2021.09.001⟩
Journal articles hal-03874129v1

Simultaneous Mechanical and Fluorescence Detection of Helicase-Catalyzed DNA Unwinding

Lulu Bi , Zhenheng Qin , Xi-Miao Hou , Mauro Modesti , Bo Sun et al.
Optical Tweezers, 2478, Springer US, pp.329-347, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2229-2_12⟩
Book sections hal-03874960v1

Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA

Ineke Brouwer , Gerrit Sitters , Andrea Candelli , Stephanie J. Heerema , Iddo Heller et al.
Nature, 2016, 535 (7613), pp.566 - 569. ⟨10.1038/nature18643⟩
Journal articles inserm-01403869v1

The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition

Lulu Bi , Zhenheng Qin , Teng Wang , Yanan Li , Xinshuo Jia et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), pp.e2116462119. ⟨10.1073/pnas.2116462119⟩
Journal articles inserm-03825786v1
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Sequential role of RAD51 paralog complexes in replication fork remodeling and restart

Matteo Berti , Federico Teloni , Sofija Mijic , Sebastian Ursich , Jevgenij Fuchs et al.
Nature Communications, 2020, 11 (1), pp.3531. ⟨10.1038/s41467-020-17324-z⟩
Journal articles inserm-02907291v1
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RADX Modulates RAD51 Activity to Control Replication Fork Protection

Kamakoti P Bhat , Archana Krishnamoorthy , Huzefa Dungrawala , Edwige B Garcin , Mauro Modesti et al.
Cell Reports, 2018, 24 (3), pp.538-545. ⟨10.1016/j.celrep.2018.06.061⟩
Journal articles hal-02144125v1
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PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF

Satish  K. Tadi , Carine Tellier-Lebègue , Clément Nemoz , Pascal Drevet , Stéphane Audebert et al.
Cell Reports, 2016, 17 (2), pp.541 - 555. ⟨10.1016/j.celrep.2016.09.026⟩
Journal articles inserm-01401845v1
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Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

Edwige B Garcin , Stéphanie Gon , Meghan Sullivan , Gregory J Brunette , Anne De Cian et al.
PLoS Genetics, 2019, 15 (10), pp.e1008355. ⟨10.1371/journal.pgen.1008355⟩
Journal articles hal-02383639v1
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Human RPA activates BLM's bidirectional DNA unwinding from a nick

Zhenheng Qin , Lulu Bi , Xi-Miao Hou , Xia Zhang , Ying Lu et al.
Journal articles hal-02533588v1
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Visualizing the Nonhomogeneous Structure of RAD51 Filaments Using Nanofluidic Channels

Louise H Fornander , Karolin B Frykholm , Joachim J Fritzsche , Joshua J Araya , Philip B Nevin et al.
Langmuir, 2016, 32 (33), pp.8403-8412. ⟨10.1021/acs.langmuir.6b01877⟩
Journal articles hal-01456267v1

Insights into the control of RAD51 nucleoprotein filament dynamics from single-molecule studies

Florian Morati , Mauro Modesti
Current Opinion in Genetics and Development, 2021, 71, pp.182-187. ⟨10.1016/j.gde.2021.09.001⟩
Journal articles hal-03438615v1

A basal-level activity of ATR links replication fork surveillance and stress response

Mauro Modesti , Yandong Yin , Wei Ting Chelsea Lee , Dipika Gupta , Huijun Xue et al.
Molecular Cell, 2021, 81 (20), pp.4243-4257.e6. ⟨10.1016/j.molcel.2021.08.009⟩
Journal articles hal-03438618v1

Human RPA activates BLM’s bidirectional DNA unwinding from a nick

Zhenheng Qin , Lulu Bi , Xi-Miao Hou , Siqi Zhang , Xia Zhang et al.
Journal articles hal-03038384v1

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

Clément Nemoz , Virginie Ropars , Philippe Frit , Amandine Gontier , Pascal Drevet et al.
Nature Structural and Molecular Biology, 2018, 25 (10), pp.971-980. ⟨10.1038/s41594-018-0133-6⟩
Journal articles hal-02143568v1
Image document

The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition

Lulu Bi , Zhenheng Qin , Teng Wang , Yanan Li , Xinshuo Jia et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), ⟨10.1073/pnas.2116462119⟩
Journal articles hal-03874779v1
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Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination

Ineke Brouwer , Hongshan Zhang , Andrea Candelli , Davide Normanno , Erwin J G Peterman et al.
Cell Reports, 2017, 18, pp.2845 - 2853. ⟨10.1016/j.celrep.2017.02.068⟩
Journal articles hal-01495423v1

Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis

Mauro Modesti , Robin Öz , Jing Wang , Raphael Guerois , Gaurav Goyal et al.
Nucleic Acids Research, 2021, 49 (5), pp.2629-2641. ⟨10.1093/nar/gkab083⟩
Journal articles hal-03438620v1

Homologous recombination–deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants

Rohit Prakash , Yashpal Rawal , Meghan Sullivan , Mckenzie Grundy , Hélène Bret et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (38), pp.e2202727119. ⟨10.1073/pnas.2202727119⟩
Journal articles inserm-03812808v1

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

Jonathan Barroso-González , Laura García-Expósito , Song My Hoang , Michelle Lynskey , Justin Roncaioli et al.
Molecular Cell, 2019, 76 (1), pp.11-26.e7. ⟨10.1016/j.molcel.2019.06.043⟩
Journal articles hal-02383646v1
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Plugged into the Ku-DNA hub: The NHEJ network

Philippe Frit , Virginie Ropars , Mauro Modesti , Jean-Baptiste Charbonnier , Patrick Calsou et al.
Progress in Biophysics and Molecular Biology, 2019, 147, pp.62-76. ⟨10.1016/j.pbiomolbio.2019.03.001⟩
Journal articles hal-02144114v1