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authIdHal_s : thierry-meinnel

Structure-activity relationship analysis and therapeutic potential of peptide deformylase inhibitors.

Adrien Boularot , Carmela Giglione , Isabelle Artaud , Thierry Meinnel
Current Opinion in Investigational Drugs, 2004, 5 (8), pp.809-22
Journal articles hal-00122346v1

Peptide deformylase as an emerging target for antiparasitic agents.

C. Giglione , T. Meinnel
Expert Opin Ther Targets, 2001, 5 (1), pp.41-57. ⟨10.1517/14728222.5.1.41⟩
Journal articles hal-00150809v1

The situation on antimicrobial agents and chemotherapy in 2002: highlights of the 42nd ICAAC.

Carmela Giglione , Thierry Meinnel
Expert Opin Ther Targets, 2002, 6 (6), pp.691-7. ⟨10.1517/14728222.6.6.691⟩
Journal articles hal-00139402v1

An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway.

Alexandre Serero , Carmela Giglione , Alessandro Sardini , Juan Martinez-Sanz , Thierry Meinnel et al.
Journal of Biological Chemistry, 2003, 278 (52), pp.52953-63. ⟨10.1074/jbc.M309770200⟩
Journal articles hal-00135708v1

Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents.

C. Giglione , M. Pierre , T. Meinnel
Molecular Microbiology, 2000, 36 (6), pp.1197-205. ⟨10.1046/j.1365-2958.2000.01908.x⟩
Journal articles hal-00162998v1
Image document

Myristoylation, an ancient protein modification mirroring eukaryogenesis and evolution

Thierry Meinnel , Cyril Dian , Carmela Giglione
Trends in Biochemical Sciences, 2020, 45 (7), pp.619-632. ⟨10.1016/j.tibs.2020.03.007⟩
Journal articles hal-02571405v1
Image document

eNergiome and N-TerPred: novel tools to improve the prediction of plastidic and mitochondrial mature N-termini,

Willy Vincent V Bienvenut , P-A Charbit , J-P Scarpelli , T. Meinnel , C. Giglione et al.
The FEBS Congress 2018, Jul 2018, Prague, Czech Republic
Conference poster hal-02381731v1

Proteome-wide probing of the dual NMT-dependent myristoylation tradeoff unveils potent, mechanism-based suicide inhibitors

Frédéric Rivière , Cyril Dian , Rémi Dutheil , Carmela Giglione , Thierry Meinnel et al.
Preprints, Working Papers, ... hal-03398842v1
Image document

N-terminal modifications, the associated processing machinery, and their evolution in plastid-containing organisms

Thierry Meinnel , Carmela Giglione
Journal of Experimental Botany, 2022, 73 (18), pp.6013-6033. ⟨10.1093/jxb/erac290⟩
Journal articles hal-03754997v1

N-myristoyltransferases inhibitory activity of ellagitannins from Terminalia bentzoe (L.) L. f. subsp. bentzoe

Cecile Apel , Jerome Bignon , Maria Concepcion Garcia-Alvarez , Sarah Ciccone , Patricia Clerc et al.
Fitoterapia, 2018, 131, pp.91--95. ⟨10.1016/j.fitote.2018.10.014⟩
Journal articles hal-02175118v1

A High Content in Lipid-modified Peripheral Proteins and Integral Receptor Kinases Features in the Arabidopsis Plasma Membrane Proteome.

Anne Marmagne , Myriam Ferro , Thierry Meinnel , Christophe Bruley , Lauriane Kuhn et al.
Molecular and Cellular Proteomics, 2007, 6 (11), pp.1980-96. ⟨10.1074/mcp.M700099-MCP200⟩
Journal articles hal-00187502v1
Image document

N-terminal acetylation status of nuclear proteins upon proteotoxic stress

Yuliya Kuchkovska , Jean-Baptiste Boyer , Thierry Meinnel , Carmela Giglione , Frédéric Frottin et al.
Protein termini: From mechanisms to biological impact, Jun 2022, Bergen, Norway. 2022
Conference poster hal-03852104v1

Synthèse du livre blanc des sciences de la vie du département des sciences de la vie de l'université Paris Saclay

Jacques Bittoun , Isabelle Bonnin , Jacques Capy , Gilles Chiocchia , Frédéric Dollé et al.
[0] 2015
Reports hal-02800505v1

Impact of the N-terminal amino acid on targeted protein degradation.

Thierry Meinnel , Alexandre Serero , Carmela Giglione
Biol Chem, 2006, 387 (7), pp.839-51. ⟨10.1515/BC.2006.107⟩
Journal articles istex hal-00118264v1

Protein lipidation meets proteomics.

Thierry Meinnel , Carmela Giglione
Frontiers in Bioscience, 2008, 13, pp.6326-40
Journal articles hal-00853809v1

Expanded impact of protein N-myristoylation in plants.

José A Traverso , Thierry Meinnel , Carmela Giglione
Plant Signaling and Behavior, 2008, 3 (7), pp.501-2
Journal articles hal-00853810v1

Functional and Developmental Impact of Cytosolic Protein N-Terminal Methionine Excision in Arabidopsis.

Simon Ross , Carmela Giglione , Michèle Pierre , Christelle Espagne , Thierry Meinnel et al.
Plant Physiology, 2005, 137, pp.623-637. ⟨10.1104/pp.104.056861⟩
Journal articles hal-00019039v1

Dynamics of post-translational modifications and protein stability in the stroma of Chlamydomonas reinhardtii chloroplasts.

Willy V Bienvenut , Christelle Espagne , Aude Martinez , Wojetec Majeran , Benoît Valot et al.
Proteomics, 2011, 11 (9), pp.1734-50. ⟨10.1002/pmic.201000634⟩
Journal articles istex hal-00851379v1

Protein N-terminal methionine excision.

C. Giglione , A. Boularot , T. Meinnel
Cellular and Molecular Life Sciences, 2004, 61 (12), pp.1455-74. ⟨10.1007/s00018-004-3466-8⟩
Journal articles istex hal-00122329v1

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state.

Frédéric Frottin , Willy V. Bienvenut , Jérôme Bignon , Eric Jacquet , Alvaro Sebastian Vaca Jacome et al.
Journal articles hal-01358428v1

Interplay between N-terminal methionine excision and FtsH protease is essential for normal chloroplast development and function in Arabidopsis.

Zach Adam , Frédéric Frottin , Christelle Espagne , Thierry Meinnel , Carmela Giglione et al.
The Plant cell, 2011, 23 (10), pp.3745-60. ⟨10.1105/tpc.111.087239⟩
Journal articles hal-00851374v1

Type 3 peptide deformylases are required for oxidative phosphorylation in Trypanosoma brucei.

Nabile Bouzaidi-Tiali , Carmela Giglione , Yannick Bulliard , Mascha Pusnik , Thierry Meinnel et al.
Molecular Microbiology, 2007, 65 (5), pp.1218-28. ⟨10.1111/j.1365-2958.2007.05867.x⟩
Journal articles hal-00184645v1

Molecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling.

Trinh V Dinh , Willy V. Bienvenut , Eric Linster , Anna Feldman-Salit , Vincent A Jung et al.
Proteomics, 2015, pp.2426-35. ⟨10.1002/pmic.201500025⟩
Journal articles hal-01464737v1

Targeted profiling of A. thaliana sub-proteomes illuminates new co- and post-translationally N-terminal Myristoylated proteins

Wojciech Majeran , Jean-Pierre Le Caer , Lalit Ponnala , Thierry Meinnel , Carmela Giglione et al.
The Plant cell, 2018, 30 (3), tpc.00523.2017. ⟨10.1105/tpc.17.00523⟩
Journal articles hal-02182304v1
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Evolution-driven versatility of N-terminal acetylation in photoautotrophs

Carmela Giglione , Thierry Meinnel
Trends in Plant Science, 2021, 26 (4), pp.375-391. ⟨10.1016/j.tplants.2020.11.012⟩
Journal articles hal-03011833v1
Image document

Comment on binding affinity determines substrate specificity and enables discovery of substrates for N-Myristoyltransferases

Thierry Meinnel
ACS Catalysis, 2022, 12 (14), pp.8195-8201. ⟨10.1021/acscatal.2c01060⟩
Journal articles hal-03754583v1

Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis.

Sonia Fieulaine , Adrien Boularot , Isabelle Artaud , Michel Desmadril , Frédéric Dardel et al.
PLoS Biology, 2011, 9 (5), pp.e1001066. ⟨10.1371/journal.pbio.1001066⟩
Journal articles hal-00851377v1

Ion mobility coupled to native mass spectrometry as a relevant tool to investigate extremely small ligand-induced conformational changes

Johann Stojko , Sonia Fieulaine , Stéphanie Petiot-Bécard , Alain van Dorsselaer , Thierry Meinnel et al.
Analyst, 2015, 140 (21), pp.7234 - 7245. ⟨10.1039/c5an01311a⟩
Journal articles hal-01432173v1

Seeking new targets for antiparasitic agents

Alexandre Serero , Carmela Giglione , Thierry Meinnel
Trends in Parasitology, 2001, 17, pp.7-8. ⟨10.1016/S1471-4922(00)01733-5⟩
Journal articles istex hal-00157196v1

Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern

Benoît Castrec , Cyril Dian , Sarah Ciccone , Coralie Ebert , Willy Bienvenut et al.
Nature Chemical Biology, 2018, 14, pp.671 - 679. ⟨10.1038/s41589-018-0077-5⟩
Journal articles cea-01873857v1