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Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters

Valentin Sencio , Arnaud Machelart , Cyril Robil , Nicolas Benech , Eik Hoffmann et al.
Gut microbes, 2022, 14 (1), ⟨10.1080/19490976.2021.2018900⟩
Journal articles hal-03862425v1
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Increased surface P2X4 receptors by mutant SOD1 proteins contribute to ALS pathogenesis in SOD1-G93A mice

Eléonore Bertin , Audrey Martinez , Anne Fayoux , Kevin Carvalho , Sara Carracedo et al.
Cellular and Molecular Life Sciences, 2022, 79 (8), pp.431. ⟨10.1007/s00018-022-04461-5⟩
Journal articles inserm-03727852v1
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Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate

Suzanne Lam , Fanny Petit , Anne-Sophie Hérard , Susana Boluda , Sabiha Eddarkaoui et al.
Acta Neuropathologica Communications, 2021, 9 (1), pp.165. ⟨10.1186/s40478-021-01266-8⟩
Journal articles inserm-03388548v1
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Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model

Antoine Leboucher , Tariq Ahmed , Emilie Caron , Anne Tailleux , Sylvie Raison et al.
Neurobiology of Disease, 2019, 125, pp.14-22. ⟨10.1016/j.nbd.2019.01.008⟩
Journal articles inserm-02350072v1

Sox2 functionally interacts with βAPP, the βAPP intracellular domain and ADAM10 at a transcriptional level in human cells

G. Sarlak , H.H. Htoo , Jean-François Hernandez , H. Iizasa , F. Checler et al.
Neuroscience, 2016, 312, pp.153-164. ⟨10.1016/j.neuroscience.2015.11.022⟩
Journal articles hal-03564404v1
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Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription

Isabel Paiva , Lucrezia Cellai , Céline Meriaux , Lauranne Poncelet , Ouada Nebie et al.
The Journal of clinical investigation, 2022, 132 (12), ⟨10.1172/JCI149371⟩
Journal articles hal-03855350v1
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The Polyherbal Wattana Formula Displays Anti-Amyloidogenic Properties by Increasing α-Secretase Activities

Htut Htut Htoo , Suveerawan Limsuvan , Onusa Thamsermsang , Jean-François Hernandez , Frédéric Checler et al.
PLoS ONE, 2017, 12 (1), pp.e0170360. ⟨10.1371/journal.pone.0170360⟩
Journal articles hal-03564506v1

Influence of Lewy Pathology on Alzheimer’s Disease Phenotype: A Retrospective Clinico-Pathological Study

Jennifer Roudil , Vincent Deramecourt , Boris Dufournet , Bruno Dubois , Mathieu Ceccaldi et al.
Journal of Alzheimer's Disease, 2018, 63 (4), pp.1317-1323. ⟨10.3233/JAD-170914⟩
Journal articles hal-03570490v1
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IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease

Helena Brigas , Miguel Ribeiro , Joana Coelho , Rui Gomes , Victoria Gomez-Murcia et al.
Cell Reports, 2021, 36 (9), pp.109574. ⟨10.1016/j.celrep.2021.109574⟩
Journal articles inserm-03366653v1
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Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview

Constance Delaby , Charlotte Teunissen , Kaj Blennow , Daniel Alcolea , Ivan Arisi et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, In press, ⟨10.1002/alz.12545⟩
Journal articles hal-03599269v1
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Searching for secondary findings: considering actionability and preserving the right not to know

Bertrand Isidor , Sophie Julia , Pascale Saugier-Veber , Paul-Loup Weil-Dubuc , Stephane Bezieau et al.
European Journal of Human Genetics, 2019, 27 (10), pp.1481-1484. ⟨10.1038/s41431-019-0438-x⟩
Journal articles hal-02904506v1
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Isolated parkinsonism is an atypical presentation of GRN and C9orf72 gene mutations Authors

Fábio Carneiro , Dario Saracino , Vincent Huin , Fabienne Clot , Cécile Delorme et al.
Parkinsonism & Related Disorders, 2020, 80, pp.73-81. ⟨10.1016/j.parkreldis.2020.09.019⟩
Journal articles hal-03146705v1
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Istradefylline protects from cisplatin-induced nephrotoxicity and peripheral neuropathy while preserving cisplatin antitumor effects

Edmone Dewaeles , Kévin Carvalho , Sandy Fellah , Jaewon Sim , Nihad Boukrout et al.
The Journal of clinical investigation, 2022, 132 (22), pp.e152924. ⟨10.1172/JCI152924⟩
Journal articles inserm-03865945v1

GnRH replacement rescues cognition in Down syndrome

Maria Manfredi-Lozano , Valerie Leysen , Michela Adamo , Isabel Paiva , Renaud Rovera et al.
Science, 2022, 377 (6610), pp.eabq4515. ⟨10.1126/science.abq4515⟩
Journal articles inserm-03841247v1

Contribution to Alzheimer's disease risk of rare variants in TREM_2, SORL_1, and ABCA_7 in 1779 cases and 1273 controls

Céline Bellenguez , Camille Charbonnier , Benjamin Grenier-Boley , Olivier Quenez , Kilan Le Guennec et al.
Neurobiology of Aging, 2017, 59, pp.220.e1-220.e9. ⟨10.1016/j.neurobiolaging.2017.07.001⟩
Journal articles hal-01760388v1
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Benzodiazepine use and neuroimaging markers of Alzheimer’s disease in nondemented older individuals: an MRI and 18F Florbetapir PET study in the MEMENTO cohort

Quentin Gallet , Vincent Bouteloup , Maxime Locatelli , Marie-Odile Habert , Marie Chupin et al.
Neuropsychopharmacology, 2022, 47 (5), pp.1114-1120. ⟨10.1038/s41386-021-01246-5⟩
Journal articles inserm-03933595v1
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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

Jan Wenzel , Josephine Lampe , Helge Müller-Fielitz , Raphael Schuster , Marietta Zille et al.
Nature Neuroscience, 2021, 24 (11), pp.1522-1533. ⟨10.1038/s41593-021-00926-1⟩
Journal articles inserm-03741941v1

Gardos channelopathy: functional analysis of a novel KCNN4 variant

Elisa Fermo , David Monedero-Alonso , Polina Petkova-Kirova , Asya Makhro , Laurent Pérès et al.
Blood Advances, 2020, 4 (24), pp.6336-6341. ⟨10.1182/bloodadvances.2020003285⟩
Journal articles hal-03767148v1
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Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial

Peter A. Ljubenkov , Lauren Edwards , Leonardo Iaccarino , Renaud La Joie , Julio C. Rojas et al.
JAMA Network Open, 2021, 4 (9), pp.e2125584. ⟨10.1001/jamanetworkopen.2021.25584⟩
Journal articles hal-03419025v1
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Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model

Hamza Benderradji , Sarra Kraiem , Emilie Courty , Sabiha Eddarkaoui , Cyril Bourouh et al.
Frontiers in Molecular Neuroscience, 2022, 15, pp.841892. ⟨10.3389/fnmol.2022.841892⟩
Journal articles inserm-03699324v1
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Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Mark K. Bakker , Jos P. Kanning , Gad Abraham , Amy E. Martinsen , Bendik S. Winsvold et al.
Journal articles hal-03999672v1
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Zero the hero: evidence for involvement of the ventromedial prefrontal cortex in affective bias for free items

V. Lenglin , S. Wong , C. O’callaghan , S. Erzinçlioğlu , M. Hornberger et al.
Journal articles hal-03921221v1

Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson's Disease.

Ilda Coku , Eugénie Mutez , Sabiha Eddarkaoui , Sébastien Carrier , Antoine Marchand et al.
Movement Disorders, 2022, ⟨10.1002/mds.29124⟩
Journal articles hal-03703786v1
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Hyperexcitability and seizures in the THY-Tau22 mouse model of tauopathy

Victoria Gomez-Murcia , Ursula Sandau , Barbara Ferry , Sandrine Parrot , Cyril Laurent et al.
Neurobiology of Aging, 2020, 94, pp.265-270. ⟨10.1016/j.neurobiolaging.2020.06.004⟩
Journal articles hal-03065490v1
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Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain

Audrey Valverde , Julie Dunys , Thomas Lorivel , Delphine Debayle , Anne-Sophie Gay et al.
Acta Neuropathologica, 2021, 141 (6), pp.823-839. ⟨10.1007/s00401-021-02308-0⟩
Journal articles hal-03239400v1
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Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains

Loan Vaillant-Beuchot , Arnaud Mary , Raphaëlle Pardossi-Piquard , Alexandre Bourgeois , Inger Lauritzen et al.
Acta Neuropathologica, 2020, ⟨10.1007/s00401-020-02234-7⟩
Journal articles hal-03001496v1

Precision of neuronal localization in 2D cell cultures by using high-performance electropolymerized microelectrode arrays correlated with optical imaging

Mahdi Ghazal , Corentin Scholaert , Corentin Dumortier , Camille Lefebvre , Nicolas Barois et al.
Biomedical Physics & Engineering Express, In press, ⟨10.1088/2057-1976/acb93e⟩
Journal articles hal-03999001v1

Plasma Amyloid Beta Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment: The BALTAZAR Study

Olivier Hanon , Jean-Sébastien Vidal , Sylvain Lehmann , Stéphanie Bombois , Bernadette Allinquant et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2022, 18, pp.2537-2550. ⟨10.1002/alz.12613⟩
Journal articles hal-03719721v1