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Structure: Internal structure identifier : 529729

Takamalaimë (Psidium acutangulum Mart ex. DC): understanding the use of an antimalarial traditional remedy from French Guiana

Emeline S Houël , Marie Fleury , Valérie Jullian , Catherine Vonthron-Sénécheau , Flore Nardella et al.
Planta Medica, 80 (10), pp.797-797, 2014
Proceedings hal-03278506v1
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Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1 H -pyrazole-5-carboxylate as an HIV-1 replication inhibitor

Jeanne Fichez , Cathia Soulié , Laurent Le Corre , Sophie Sayon , Stéphane Priet et al.
RSC Medicinal Chemistry, 2020, 11 (5), pp.577-582. ⟨10.1039/D0MD00025F⟩
Journal articles hal-03030936v1

beta PIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells

Fanny Momboisse , Etienne Lonchamp , Valerie Calco , Mara Ceridono , Nicolas Vitale et al.
Journal of Cell Science, 2009, 122 (6), pp.798-806. ⟨10.1242/jcs.038109⟩
Journal articles hal-02644575v1
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Diastereoselective Synthesis of Nonplanar 3-Amino-1,2,4-oxadiazine Scaffold: Structure Revision of Alchornedine

Shuang-Qi Tang , Maeva Leloire , Severine Schneider , Julie Mohr , Jacques Bricard et al.
Journal of Organic Chemistry, In press, ⟨10.1021/acs.joc.0c01764⟩
Journal articles hal-03021041v1

A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor

Christel Valencia , Céline Dujet , Jean-François Margathe , Xavier Iturrioz , Thomas Roux et al.
ChemMedChem, 2017, 12 (12), pp.925-931. ⟨10.1002/cmdc.201700106⟩
Journal articles hal-02153692v1
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LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism

Marie-Céline Frantz , Lucie P. Pellissier , Elsa Pflimlin , Stéphanie Loison , Jorge Gandía et al.
Journal of Medicinal Chemistry, 2018, 61 (19), pp.8670-8692. ⟨10.1021/acs.jmedchem.8b00697⟩
Journal articles hal-02366272v1
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Target-focused library design by pocket-applied computer vision and fragment deep generative linking

Merveille Eguida , Christel Schmitt-Valencia , Marcel Hibert , Pascal Villa , Didier Rognan et al.
Journal of Medicinal Chemistry, In press, ⟨10.1021/acs.jmedchem.2c00931⟩
Journal articles hal-03830359v1

Annexin A2 Egress during Calcium-Regulated Exocytosis in Neuroendocrine Cells

Marion Gabel , Cathy Royer , Tamou Thahouly , Valérie Calco , Stéphane Gasman et al.
Cells, 2020, 9 (9), ⟨10.3390/cells9092059⟩
Journal articles hal-03360661v1

Molecular connection between calcium-regulated exocytosis and compensatory endocytosis in neuroendocrine cells

Stephane Gasman , Sébastien Houy , Catherine Edith Estay Ahumada , Pauline Croise , Valerie Calco et al.
Journal of Neurochemistry, 2015, 134, pp.74-75
Journal articles hal-02922236v1
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Antiallodynic action of phosphodiesterase inhibitors in a mouse model of peripheral nerve injury

Salim Megat , Sylvain Hugel , Sarah Journée , Yohann Bohren , Adrien Lacaud et al.
Neuropharmacology, 2022, 205, pp.108909. ⟨10.1016/j.neuropharm.2021.108909⟩
Journal articles hal-03842284v1

The Rho Guanine Nucleotide Exchange Factors Intersectin 1L and beta-Pix Control Calcium-Regulated Exocytosis in Neuroendocrine PC12 Cells

F Momboisse , Stéphane Ory , M Ceridono , Valerie Calco , Nicolas Vitale et al.
Cellular and Molecular Neurobiology, 2010, 30 (8), pp.1327-1333
Journal articles hal-02922242v1

Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia

Pierre Regenass , Dayana Abboud , Francois Daubeuf , Christine Lehalle , Patrick Gizzi et al.
Journal of Medicinal Chemistry, 2018, 61 (17), pp.7671-7686. ⟨10.1021/ACS.JMEDCHEM.8B00657⟩
Journal articles hal-02366281v1
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Liposomal encapsulation of trans-crocetin enhances oxygenation in patients with COVID-19-related ARDS receiving mechanical ventilation

Paul-Michel Mertes , Olivier Collange , Pierre Coliat , Mainak Banerjee , Marie-Charlotte Diringer et al.
Journal of Controlled Release, 2021, 336, pp.252-261. ⟨10.1016/j.jconrel.2021.06.033⟩
Journal articles hal-03767483v1

Overexpression of the MSK1 Kinase in Patients With Chronic Lung Allograft Dysfunction and Its Confirmed Role in a Murine Model

Simona Nemska , François Daubeuf , Adeline Obrecht , Dominique Israel-Biet , Marc Stern et al.
Transplantation, 2021, 105 (6), pp.1212-1224. ⟨10.1097/TP.0000000000003606⟩
Journal articles hal-03536457v1
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High-throughput screening for extracellular inhibitors of the FLT3 receptor tyrosine kinase reveals chemically diverse and druggable negative allosteric modulators

Romain Hany , Jean-Philippe Leyris , Guillaume Bret , Sylvie Mallié , Chamroeun Sar et al.
ACS Chemical Biology, 2022, 17 (3), pp.709-722. ⟨10.1021/acschembio.2c00048⟩
Journal articles hal-03747971v1

Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3-Mutated Gliomas Recreate the Patient Tumor Complexity

Anne-Florence Blandin , Aurélie Durand , Marie Litzler , Aurélien Tripp , Eric Guérin et al.
Cancers, 2019, 11 (12), pp.1875. ⟨10.3390/cancers11121875⟩
Journal articles hal-03098718v1
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Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians

Emeline Houël , Flore Nardella , Valérie Jullian , Alexis Valentin , Catherine Vonthron-Sénécheau et al.
Journal of Ethnopharmacology, 2016, 187, pp.241-248. ⟨10.1016/j.jep.2016.04.053⟩
Journal articles hal-01313006v1

Vers un nouveau traitement des mucopolysaccharidoses ? Recherche d’inhibiteurs de la β1,4-galactosyltransférase 7 (β4GalT7) par des approches combinées de criblage expérimental et virtuel

Sandrine Gulberti , Christel Valencia-Schmitt , Pascal Villa , Isaure Chauvot de Beauchêne , Bernard Maigret et al.
Rencontres RARE 2021, Oct 2021, Paris/virtuel, France
Conference poster hal-03522390v1

New contributions to the drug profile of TNFα inhibitor SPD304: Affinity, selectivity and ADMET considerations

Aïda Mascret , Hadley Mouhsine , Ghada Attia , Damien Cabrera , Mohamed Benchekroun et al.
European Journal of Pharmacology, 2021, 907, pp.174285. ⟨10.1016/j.ejphar.2021.174285⟩
Journal articles hal-03417296v1
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Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

Laurent Mailly , Fei Xiao , Joachim Lupberger , G Wilson , P Aubert et al.
Nature Biotechnology, 2015, 33 (5), pp.549-554. ⟨10.1038/nbt.3179⟩
Journal articles hal-02492425v1
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Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime

André-Guilhem Calas , Anne-Sophie Hanak , Nina Jaffré , Aurélie Nervo , José Dias et al.
Biomolecules, 2020, 10 (6), pp.858. ⟨10.3390/biom10060858⟩
Journal articles hal-03127255v1
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A strategy to discover decoy chemokine ligands with an anti-inflammatory activity

Dayana Abboud , Francois Daubeuf , Quoc Tuan Do , Valérie Utard , Pascal Villa et al.
Scientific Reports, 2015, 5, pp.14746. ⟨10.1038/srep14746⟩
Journal articles hal-02193983v1
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Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells

Maria Zeniou , Marie Fève , Samir Mameri , Jihu Dong , Christophe Salomé et al.
PLoS ONE, 2015, 10 (8), pp.e0134793. ⟨10.1371/journal.pone.0134793⟩
Journal articles hal-01223842v1
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Comparative Study of the Synthesis and Structural and Physicochemical Properties of Diketopiperazines vs Aza-diketopiperazines

Pierre Regenass , Damien Bosc , Stéphanie Riché , Patrick Gizzi , Marcel Hibert et al.
Journal of Organic Chemistry, 2017, 82 (6), pp.3239-3244. ⟨10.1021/acs.joc.6b02895⟩
Journal articles hal-03563479v1

Daunorubicin reduces MBNL1 titration by expanded CUG repeat RNA and rescues cardiac dysfunctions in a Drosophila model of myotonic dystrophy

M. Chakraborty , Chantal Sellier , Michel Ney , Pascal Villa , Nicolas Charlet-Berguerand et al.
Disease Models & Mechanisms, 2018, ⟨10.1242/dmm.032557⟩
Journal articles hal-03339524v1
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Identification of an N -acylated- D Arg-Leu-NH 2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia

Raphaëlle Quillet , Séverine Schneider , Valérie Utard , Armand Drieu La Rochelle , Khadija Elhabazi et al.
Journal of Medicinal Chemistry, 2021, 64 (11), pp.7555-7564. ⟨10.1021/acs.jmedchem.1c00256⟩
Journal articles hal-03363456v1

Context-dependent function of TSLP and IL-1β in skin allergic sensitization and atopic march

Justine Segaud , Wenjin Yao , Pierre Marschall , François Daubeuf , Christine Lehalle et al.
Nature Communications, 2022, 13 (1), pp.4703. ⟨10.1038/s41467-022-32196-1⟩
Journal articles hal-03862150v1
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A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity

Tony Rady , Lorenzo Turelli , Marc Nothisen , Elisabetta Tobaldi , Stéphane Erb et al.
Bioconjugate Chemistry, 2022, ⟨10.1021/acs.bioconjchem.2c00314⟩
Journal articles hal-03783825v1

Biosynthesis of the pyoverdine siderophore of Pseudomonas aeruginosa involves precursors with a myristic or a myristoleic acid chain

Melissa Hannauer , Mathias Schaefer , Francoise Hoegy , Patrick Gizzi , Patrick Wehrung et al.
FEBS Letters, 2011, 586 (1), pp.96-101. ⟨10.1016/j.febslet.2011.12.004⟩
Journal articles hal-02981372v1

Neuroendocrine tumors and secretion: what potential links?

Stephane Gasman , Pauline Croise , Sébastien Houy , J Lanoix , Valerie Calco et al.
Journal of Neurochemistry, 2015, 134 (Special issue), pp.230-231
Journal articles hal-02925264v1