Search - Archive ouverte HAL Access content directly

Filter your results

128 Results
Structure: Internal structure identifier : 542026
Image document

Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

Thibaut Larcher , Aude Lafoux , Laurent Tesson , Séverine Remy , Virginie Thepenier et al.
PLoS ONE, 2014, 9 (10), pp.e110371. ⟨10.1371/journal.pone.0110371⟩
Journal articles inserm-02164371v1
Image document

Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures

C. Saintomé , Patrizia Alberti , N. Guinot , P. Lejault , J. Chatain et al.
Chemical Communications, 2018, 54 (15), pp.1897-1900. ⟨10.1039/c7cc07048a⟩
Journal articles mnhn-02308805v1

Biophysical analysis of Gaussia luciferase bioluminescence mechanisms using a non-oxidizable coelenterazine

Kyoko Takatsu , Naohiro Kobayashi , Nan Wu , Yves Janin , Toshio Yamazaki et al.
BBA Advances, 2023, 3, pp.100068. ⟨10.1016/j.bbadva.2022.100068⟩
Journal articles hal-03978433v1
Image document

Utilisation de technologies d'édition du génome afin de générer des cardiomyocytes matures à partir de cellules souches pluripotentes humaines induites

Ahmed Khedher
Biotechnologie. Université Paris-Saclay, 2021. Français. ⟨NNT : 2021UPASL002⟩
Theses tel-03948124v1
Image document

On Reuben G. Jones synthesis of 2-hydroxypyrazines

Pierre Legrand , Yves Janin
Journées de Chimie Organique 2022, Nov 2022, Palaiseau, France
Conference poster hal-03932333v1
Image document

Gene Tagging with the CRISPR-Cas9 System to Facilitate Macromolecular Complex Purification

Sylvain Geny , Simon Pichard , Arnaud Poterszman , Jean-Paul Concordet
Methods in molecular biology (Clifton, N.J.), 2021, 2305, pp.153-174. ⟨10.1007/978-1-0716-1406-8_8⟩
Journal articles hal-03706664v1
Image document

Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis

Chloé Subecz , Jian-Sheng Sun , Lauréline Roger
Human Molecular Genetics, 2021, 30 (3-4), pp.172-181. ⟨10.1093/hmg/ddab008⟩
Journal articles mnhn-03879689v1
Image document

Strand switching mechanism of Pif1 helicase induced by its collision with a G-quadruplex embedded in dsDNA

Jessica Valle-Orero , Martin Rieu , Phong Lan Thao Tran , Alexandra Joubert , Saurabh Raj et al.
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac667⟩
Journal articles hal-03576966v2
Image document

Constrained G4 structures unveil topology specificity of known and new G4 binding proteins

A. Pipier , A. Devaux , T. Lavergne , A. Adrait , Y. Couté et al.
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-92806-8⟩
Journal articles hal-03369749v1

Genome Editing and Dialogic Responsibility: “What's in a Name?”

Alessandro Blasimme , Ignacio Anegon , Jean-Paul Concordet , John de Vos , Anne Dubart-Kupperschmitt et al.
American Journal of Bioethics, 2015, 15 (12), pp.54 - 57. ⟨10.1080/15265161.2015.1103811⟩
Journal articles hal-01893149v1

Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells

Carine Giovannangeli , Anna Sole , Sandrine Grossetête , Maxime Heintzé , Loelia Babin et al.
Cancer Research, 2021, 81 (19), pp.4994-5006. ⟨10.1158/0008-5472.CAN-20-3837⟩
Journal articles mnhn-03451898v1
Image document

Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex

Phong Lan Thao Tran , Martin Rieu , Samar Hodeib , Alexandra Joubert , Jimmy Ouellet et al.
Nucleic Acids Research, In press, ⟨10.1093/nar/gkab306⟩
Journal articles hal-03214603v1
Image document

Identifying G-Quadruplex-DNA-Disrupting Small Molecules

Jérémie Mitteaux , Pauline Lejault , Filip Wojciechowski , Alexandra Joubert , Julien Boudon et al.
Journal of the American Chemical Society, 2021, 143 (32), pp.12567-12577. ⟨10.1021/jacs.1c04426⟩
Journal articles hal-03321473v1

ATP-Independent Cooperative Binding of Yeast Isw1a to Bare and Nucleosomal DNA

Anne de Cian , Elise Praly , Fangyuan Ding , Vijender Singh , Christophe Lavelle et al.
PLoS ONE, 2012, 7 (2), pp.e31845. ⟨10.1371/journal.pone.0031845⟩
Journal articles hal-03065210v1


Hervé This, Vo Kientza , Alan L. Kelly , Roisin Burke R. , Christophe Lavelle
Handbook of Molecular Gastronomy, 2021, 9780429168703
Book sections hal-03231908v1
Image document

Characterization of post-edited cells modified in the TFAM gene by CRISPR/Cas9 technology in the bovine model

Vanessa Cristina de Oliveira , Clésio Gomes Mariano Junior , José Ernesto Belizário , José Eduardo Krieger , Fabiana Fernandes Bressan et al.
PLoS ONE, 2020, 15 (7), pp.e0235856. ⟨10.1371/journal.pone.0235856⟩
Journal articles inserm-02914689v1
Image document

Genome-wide prediction of DNA mutation effect on nucleosome positions for yeast synthetic genomics

Etienne Routhier , Edgard Pierre , Ghazaleh Khodabandelou , Julien Mozziconacci
Genome Research, 2021, 31 (2), pp.317-326. ⟨10.1101/gr.264416.120⟩
Journal articles hal-03158738v1
Image document

Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression

Jérémy Sandoz , Zita Nagy , Philippe Catez , Gizem Caliskan , Sylvain Geny et al.
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-09270-2⟩
Journal articles hal-02348130v1

Folding and Persistence Time of Intramolecular G-Quadruplexes Transiently Embedded in a DNA duplex

Phong Lan Thao Tran , Martin Rieu , Samar Hodeib , Alexandra Joubert , Jimmy Ouellet et al.
Preprints, Working Papers, ... hal-03102069v1
Image document

GGGCTA repeats can fold into hairpins poorly unfolded by replication protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres

Jean Chatain , Alain Blond , Anh Tuân Phan , Carole Saintomé , Patrizia Alberti et al.
Nucleic Acids Research, 2021, ⟨10.1093/nar/gkab518⟩
Journal articles hal-03278441v1
Image document

Identification of hemicatenane-specific binding proteins by fractionation of Hela nuclei extracts

Oumayma Rouis , Cedric Broussard , Francois Guillonneau , Jean-Baptiste Boulé , Emmanuelle Delagoutte et al.
Biochemical Journal, 2020, 477 (2), pp.509-524. ⟨10.1042/BCJ20190855⟩
Journal articles mnhn-02371714v2

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux

Raya Ahmed , Lauréline Roger , Pedro Costa del Amo , Kelly Miners , Rhiannon Jones et al.
Cell Reports, 2016, 17 (11), pp.2811-2818. ⟨10.1016/j.celrep.2016.11.037⟩
Journal articles hal-03204491v1

Escape from Telomere-Driven Crisis Is DNA Ligase III Dependent

Rhiannon e. Jones , Sehyun Oh , Julia w. Grimstead , Jacob Zimbric , Lauréline Roger et al.
Cell Reports, 2014, 8 (4), pp.1063-1076. ⟨10.1016/j.celrep.2014.07.007⟩
Journal articles hal-03204504v1

Extensive Telomere Erosion in the Initiation of Colorectal Adenomas and Its Association With Chromosomal Instability

Lauréline Roger , Rhiannon Jones , Nicole Heppel , Geraint Williams , Julian Sampson et al.
JNCI: Journal of the National Cancer Institute, 2013, 105 (16), pp.1202-1211. ⟨10.1093/jnci/djt191⟩
Journal articles hal-03204507v1
Image document

CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis

Antoine Mérien , Julie Tahraoui-Bories , Michel Cailleret , Jean-Baptiste Dupont , Céline Leteur et al.
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Journal articles hal-03830948v1
Image document

Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3′ toward 5′, a feature due to a 3′-end binding preference and to structuring of telomeric DNA

Jean Chatain , Georges Hatem , Emmanuelle Delagoutte , Jean-François Riou , Patrizia Alberti et al.
Nucleic Acids Research, 2021, 49, pp.10735 - 10746. ⟨10.1093/nar/gkab768⟩
Journal articles mnhn-03383266v1
Image document

Tagging Proteins with Fluorescent Reporters Using the CRISPR/Cas9 System and Double-Stranded DNA Donors

Sylvain Geny , Simon Pichard , Alice Brion , Jean-Baptiste Renaud , Sophie Jacquemin et al.
Multiprotein Complexes, pp.39-57, 2021, ⟨10.1007/978-1-0716-1126-5_3⟩
Book sections hal-03092017v1
Image document

Disease modeling by efficient genome editing using a near PAM-less base editor in vivo

Marion Rosello , Malo Serafini , Luca Mignani , Dario Finazzi , Carine Giovannangeli et al.
Nature Communications, 2022, 13 (1), pp.3435. ⟨10.1038/s41467-022-31172-z⟩
Journal articles mnhn-03868574v2
Image document

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Panagiotis Antoniou , Giulia Hardouin , Pierre Martinucci , Giacomo Frati , Tristan Felix et al.
Nature Communications, 2022, 13 (1), pp.6618. ⟨10.1038/s41467-022-34493-1⟩
Journal articles mnhn-03868573v1
Image document

Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation

Patrick Torbey , Elodie Thierion , Samuel Collombet , Anne de Cian , Carole Desmarquet-Trin-Dinh et al.
PLoS Genetics, 2018, 14 (8), pp.e1007581. ⟨10.1371/journal.pgen.1007581⟩
Journal articles hal-01876045v1