Synthesis and cytotoxicity studies of novel N-arylbenzo[ h]quinazolin-2-amines - SFR Biosit - Biologie et Santé CNRS UMS 3480
Article Dans Une Revue Beilstein Journal of Organic Chemistry Année : 2024

Synthesis and cytotoxicity studies of novel N-arylbenzo[ h]quinazolin-2-amines

Résumé

In this paper, we report a short and efficient synthesis of novel N-arylbenzo[h]quinazoline-2-amines. We have prepared a focused library of nineteen representative examples which have been submitted to cytotoxicity assays against a representative panel of eight cancer cell lines and several molecules gave attractive results in this area.

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Chimie organique
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hal-04772032 , version 1 (07-11-2024)

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Battini Veeraiah, Kishore Ramineni, Dabbugoddu Brahmaiah, Nangunoori Sampath Kumar, Hélène Solhi, et al.. Synthesis and cytotoxicity studies of novel N-arylbenzo[ h]quinazolin-2-amines. Beilstein Journal of Organic Chemistry, 2024, 20, pp.2592-2598. ⟨10.3762/bjoc.20.218⟩. ⟨hal-04772032⟩
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