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Article Dans Une Revue Nanomedicine Année : 2015

Gadolinium-based nanoparticles for theranostic MRI-radiosensitization

Résumé

A rapid development of gadolinium-based nanoparticles is observed due to their attractive properties as MRI-positive contrast agents. Indeed, they display high relaxivity, adapted biodistribution and passive uptake in the tumor thanks to enhanced permeability and retention effect. In addition to these imaging properties, it has been recently shown that they can act as effective radiosensitizers under different types of irradiation (radiotherapy, neutron therapy or hadron therapy). These new therapeutic modalities pave the way to therapy guided by imaging and to personalized medicine.
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Dates et versions

hal-01275075 , version 1 (18-02-2016)

Identifiants

Citer

François Lux, Lucie Sancey, Andrea Bianchi, Yannick Crémillieux, Stéphane Roux, et al.. Gadolinium-based nanoparticles for theranostic MRI-radiosensitization. Nanomedicine, 2015, 10 (11), pp.1801-1815. ⟨10.2217/NNM.15.30⟩. ⟨hal-01275075⟩
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