Welcome to the Collection
of LBPC-PM
The Laboratory of Physical and Chemical Biology of Membrane Proteins (UMR7099) brings together biologists, physicists and chemists in one location and develops interdisciplinary approaches to understand the function, dynamics and atomic structure of complex membrane systems.
We study the structure and dynamics of membrane barriers that are responsible for many fundamental processes in life: energy conversion from sunlight, substrate oxidation in mitochondria, cell signaling, uptake of vital nutrients, and release of toxic molecules by bacteria. Our fundamental research helps
i) to understand many human diseases: obesity, cancers, neurological and inflammatory diseases and
ii) to build tools to fight bacterial infections (antibiotic resistance, vaccines).
Research within the laboratory is organized in four main themes.
Energy coupling & supramolecular organization of respiratory chain complexes
|
Molecular pathway of GPGRs
|
Transport& membrane dynamics in bacteria
|
Molecular synthesis of Amphipols and ligands & biophysical approaches
|