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Article Dans Une Revue Applied Physics Letters Année : 2001

Synchrotron hard x-ray microprobe: Fluorescence imaging of single cells

Résumé

Imaging of trace elements in single cells was achieved by synchrotron-induced x-ray fluorescence ~SXRF! in the hard x-ray range. Monochromatic and ‘‘pink'' excitations at 14 keV were used with compound refractive lenses resulting in a 1310 mm2 beam size. The experiment shows that SXRF is well suited for microanalysis of freeze-dried cells, and demonstrated high accuracy in quantitative imaging of trace element in cells treated with pharmacological doses of an iodine-labeled anticancer drug.
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Dates et versions

hal-00137459 , version 1 (20-03-2007)

Identifiants

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Sylvain Bohic, Alexandre Simionovici, A. Snigirev, Richard Ortega, Guillaume Devès, et al.. Synchrotron hard x-ray microprobe: Fluorescence imaging of single cells. Applied Physics Letters, 2001, 78, pp.3544-3546. ⟨10.1063/1.1366362⟩. ⟨hal-00137459⟩

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