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Article Dans Une Revue Science Année : 2011

Evidence for Network Evolution in an Arabidopsis Interactome Map

Pascal Braun (1, 2) , Anne-Ruxandra Carvunis (1, 3) , Benoit Charloteaux (1, 2, 4) , Matija Dreze (1, 2, 5) , Joseph R. Ecker (6, 7) , David E. Hill (1, 2) , Frederick P. Roth (1, 8) , Marc Vidal (1, 2) , Mary Galli (6) , Padmavathi Balumuri (9) , Vanessa Bautista (6) , Jonathan D. Chesnut (9) , Rosa Cheuk Kim (6) , Chris de Los Reyes (6) , Patrick Gilles (9) , Christopher J. Kim (6) , Uday Matrubutham (9) , Jyotika Mirchandani (9) , Eric Olivares (9) , Suswapna Patnaik (9) , Rosa Quan (6) , Gopalakrishna Ramaswamy (9) , Paul Shinn (6) , Geetha M. Swamilingiah (9) , Stacy Wu (6) , Danielle Byrdsong (1, 2) , Amélie Dricot (1, 2) , Melissa Duarte (1, 2) , Fana Gebreab (1, 2) , Bryan J. Gutierrez (1, 2) , Andrew Macwilliams (1, 2) , Dario Monachello (10, 11) , M. Shahid Mukhtar (12) , Matthew M. Poulin (1, 2) , Patrick Reichert (1, 2) , Viviana Romero (1, 2) , Stanley Tam (1, 2) , Selma Waaijers (1, 2) , Evan M. Weiner (1, 2) , Michael E. Cusick (1, 2) , Murat Taşan (8) , Junshi Yazaki (7) , Yong-Yeol Ahn (1, 13) , Albert-László Barabási (1, 13) , Huaming Chen (6) , Jeffery L. Dangl (12) , Changyu Fan (1, 2) , Lantian Gai (6) , Gourab Ghoshal (1, 13) , Tong Hao (1, 2) , Claire Lurin (10, 11) , Tijana Milenkovic (14) , Jonathan Moore (15) , Samuel J. Pevzner (1, 2, 16) , Natasa Przulj (17) , Sabrina Rabello (1, 13) , Edward A. Rietman (1, 2) , Thomas Rolland (1, 2) , Balaji Santhanam (1, 2) , Robert J. Schmitz (7) , William Spooner (18, 19) , Joshua Stein (18) , Jean Vandenhaute (5) , Doreen Ware (18)
Patrick Gilles
  • Fonction : Auteur
Eric Olivares
  • Fonction : Auteur

Résumé

Plants have unique features that evolved in response to their environments and ecosystems. A full account of the complex cellular networks that underlie plant-specific functions is still missing. We describe a proteome-wide binary protein-protein interaction map for the interactome network of the plant Arabidopsis thaliana containing about 6200 highly reliable interactions between about 2700 proteins. A global organization of plant biological processes emerges from community analyses of the resulting network, together with large numbers of novel hypothetical functional links between proteins and pathways. We observe a dynamic rewiring of interactions following gene duplication events, providing evidence for a model of evolution acting upon interactome networks. This and future plant interactome maps should facilitate systems approaches to better understand plant biology and improve crops.

Dates et versions

hal-02651738 , version 1 (29-05-2020)

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Citer

Pascal Braun, Anne-Ruxandra Carvunis, Benoit Charloteaux, Matija Dreze, Joseph R. Ecker, et al.. Evidence for Network Evolution in an Arabidopsis Interactome Map. Science, 2011, 333 (6042), pp.601 - 607. ⟨10.1126/science.1203877⟩. ⟨hal-02651738⟩
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