Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
Résumé
Highlights d HP1 has only a weak capacity to form droplets in living cells d Size, accessibility, and compaction of heterochromatin foci are independent of HP1 d Heterochromatin compaction is ''digital'' and can toggle between two distinct states d Methodological framework to assess hallmarks of phase separation in living cells
Domaines
Sciences du Vivant [q-bio]
Origine : Publication financée par une institution