Adapted NUTS have been produced as part of the H2020 RISIS project. Compared with NUTS3, it focuses on large agglomerations, while remaining fully compatible with the EUROSTAT NUTS regional classification. This compatibility allows combining data with regional statistics (at NUTS3 level, 2021 edition) from EUROSTAT. “More precisely, the classification includes EUROSTAT metropolitan regions (based on the aggregation of NUTS3-level regions) and NUTS2 regions for the remaining areas; further, a few additional centers for knowledge production […] have been singled out at NUTS3 level. The resulting classification is therefore more fine-grained than NUTS2 in the areas with sizeable knowledge production, but at the same time recognizes the central role of metropolitan areas in knowledge production.” (Lepori, B., & Guerini, M., 2020). See https://docs.cortext.net/cortext-geospatial-exploration-tool/#risis-adapted-nuts-2021 for more information.