Stereoselective and Catalytic Access to β-Enaminones: An Entry to Pyrimidines
Résumé
We describe herein a highly stereoselective access to Cbz-protected β-enaminones 2 based on the NaOH catalyzed rearrangement of propargylic hydroxylamines 1. The synthetic potential of these β-enaminones is illustrated in an original synthesis of pyrimidines.