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Article Dans Une Revue Investigative Ophthalmology & Visual Science Année : 2015

Influence of blood pressure and vascular resistance on the response to medications lowering intraocular pressure: a mathematical model

Résumé

Elevated intraocular pressure (IOP) can be reduced via medications modulating aqueous humor (AH) flow, but the drug efficacy varies significantly among patients. Many factors may influence drug efficacy, including mean arterial pressure (MAP) and systemic vascular resistance (sVR). Here we propose a mathematical model to theoretically investigate the individual roles played by MAP and sVR on the response to IOP-lowering medications.
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Dates et versions

hal-01217002 , version 1 (18-10-2015)

Identifiants

  • HAL Id : hal-01217002 , version 1

Citer

G. Guidoboni, Alon Harris, Christophe Prud'Homme, Brent Siesky, Riccardo Sacco, et al.. Influence of blood pressure and vascular resistance on the response to medications lowering intraocular pressure: a mathematical model. Investigative Ophthalmology & Visual Science, 2015, 56 (7). ⟨hal-01217002⟩
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