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Article Dans Une Revue Veterinary Pathology Année : 2018

Coxiella burnetii in Infertile Dairy Cattle With Chronic Endometritis.

Davide de Biase
  • Fonction : Auteur
Alessandro Costagliola
  • Fonction : Auteur
Fabio del Piero
  • Fonction : Auteur
Rossella Di Palo
  • Fonction : Auteur
Domenico Coronati
  • Fonction : Auteur
Giorgio Galiero
  • Fonction : Auteur
Barbara Degli Uberti
  • Fonction : Auteur
Maria Gabriella Lucibelli
  • Fonction : Auteur
Annalisa Fabbiano
  • Fonction : Auteur
Bernard Davoust
Orlando Paciello
  • Fonction : Auteur

Résumé

Coxiella burnetii is an obligate intracellular pathogen and the cause of Q fever in many animal species and humans. Several studies have reported the association between C. burnetii and abortion, premature delivery, stillbirth, and weak offspring. However, no solid evidence indicates that C. burnetii causes endometritis, subfertility, and retained fetal membranes. For this study, histopathological and PCR evaluation were performed on 40 uterine biopsies from dairy cattle with poor fertility. Uterine swabs were concurrently tested with microbiology assays. The endometrial biopsies of 30 cows did not have any significant lesions, and no pathogens were identified by aerobic bacterial culture and PCR. Ten cows were PCR-positive for C. burnetii and negative for other pathogens by aerobic bacterial culture and PCR. These 10 cases revealed a mild to severe chronic endometritis admixed with perivascular and periglandular fibrosis. Immunohistochemical evaluation of C. burnetii PCR-positive biopsies identified, for the first time, the presence of intralesional and intracytoplasmic C. burnetii in macrophages in the endometrium of cattle.

Dates et versions

hal-01801454 , version 1 (28-05-2018)

Identifiants

Citer

Davide de Biase, Alessandro Costagliola, Fabio del Piero, Rossella Di Palo, Domenico Coronati, et al.. Coxiella burnetii in Infertile Dairy Cattle With Chronic Endometritis.. Veterinary Pathology, 2018, pp.300985818760376. ⟨10.1177/0300985818760376⟩. ⟨hal-01801454⟩

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