Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses - CNRS - Centre national de la recherche scientifique Accéder directement au contenu
Article Dans Une Revue Molecular Biology and Evolution Année : 2020

Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses

1 UNIL - Université de Lausanne = University of Lausanne
2 UPF - Universitat Pompeu Fabra [Barcelona]
3 University of Freiburg [Freiburg]
4 Edin. - University of Edinburgh
5 University of St Andrews [Scotland]
6 Unibas - Université de Bâle = University of Basel = Basel Universität
7 IBMC - Instituto de Biologia Molecular e Celular - institute for molecular and cell biology [Porto, Portugal]
8 LBBE - Laboratoire de Biométrie et Biologie Evolutive - UMR 5558
9 Fondazione Edmund Mach [San Michele all'Adige]
10 UKMA - National University of Kyiv-Mohyla Academy
11 Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» [Moscow, Russia]
12 Aarhus University [Aarhus]
13 UB - Universitat de Barcelona
14 Universidade do Porto = University of Porto
15 EGCE - Evolution, génomes, comportement et écologie
16 Skane University Hospital [Lund]
17 Department of Animal and Plant Sciences [Sheffield]
18 Georg-August-University = Georg-August-Universität Göttingen
19 LMU - Ludwig Maximilian University [Munich] = Ludwig Maximilians Universität München
20 IGC - Instituto Gulbenkian de Ciência [Oeiras]
21 University of Virginia
22 UAB - Universitat Autònoma de Barcelona = Autonomous University of Barcelona = Universidad Autónoma de Barcelona
23 Hacettepe University = Hacettepe Üniversitesi
24 School of Life Sciences [Lausanne]
25 WUR - Wageningen University and Research [Wageningen]
26 University of Haifa [Haifa]
27 University of Pennsylvania
28 University of Liverpool
Maaria Kankare
Michael G Ritchie
Paul Schmidt
Josefa González

Résumé

Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster. Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterize variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples.
Fichier principal
Vignette du fichier
msaa120.pdf (5.29 Mo) Télécharger le fichier
Origine Publication financée par une institution

Dates et versions

hal-04615912 , version 1 (19-11-2020)
hal-04615912 , version 2 (18-06-2024)

Licence

Identifiants

Citer

Martin Kapun, Maite G Barrón, Fabian Staubach, Darren J Obbard, R Axel W Wiberg, et al.. Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses. Molecular Biology and Evolution, 2020, 37 (9), pp.2661-2678. ⟨10.1093/molbev/msaa120⟩. ⟨hal-04615912v2⟩
146 Consultations
108 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More