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Article Dans Une Revue International Journal of Pharmaceutical Sciences and Research Année : 2020

Secondary Metabolites from Leaves of Polyalthia lateriflora and Their Antimicrobial Activity

Résumé

The study aimed to isolate and identify the phytochemical components of Polyalthia lateriflora leaves and evaluate the antimicrobial activity. Six well-known compounds, including three triterpene lupeol (1) betulinic acid (2), β-Sitosterol-β-D-glucoside (3) and three oxoaporphine alkaloids O-methylmoschotaline (4), liriodenine (5) and atherosperminine (6). Structural elucidation of compounds were established through spectroscopic techniques such as 1D and 2D NMR (1H and 13C, DEPT, COSY, NOESY, HMBC, HMQC), IR and LC-MS. The isolated compounds and crude extracted were tested for their antibacterial potential against several microorganisms including P. aeruginosa, E. coli, s, S. aureus, B. subtilis and Saccharomyces cerevisiae and its showed significant inhibition toward the organisms species with different concentration range.

Domaines

Chimie

Dates et versions

hal-03471222 , version 1 (08-12-2021)

Identifiants

Citer

Saripah Salbiah Syed Abdul Azziz, Ahmed Kareem Obaid Aldulaimi, Saadon Abdulla Aowda, Yuhanis Mhd Bakri, Ali Arkan Majhool, et al.. Secondary Metabolites from Leaves of Polyalthia lateriflora and Their Antimicrobial Activity. International Journal of Pharmaceutical Sciences and Research, 2020, 11 (3), pp.4353-4358. ⟨10.26452/ijrps.v11i3.2652⟩. ⟨hal-03471222⟩
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