Investigation of UV Light-Promoted Synthesis of α-Sulfonyl Amides from N -Sulfonyl Ynamides
Résumé
UV Light-promoted synthesis of α-sulfonyl amides from N-sulfonyl ynamides without any additives is reported. The reaction proceeds through a radical chain mechanism involving the photo-induced cleavage of the nitrogen-sulfur bond, addition of electrophilic sulfonyl radical to the triple bond of the ynamide followed by beta-fragmentation of the sulfonyl group leading to a ketenimine hydrated upon work-up. This highly efficient rearrangement leads, after acidic treatment, to a wide range of α-sulfonyl amides in high yields.
Domaines
Chimie organiqueOrigine | Fichiers produits par l'(les) auteur(s) |
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